Evaluation of the Elderly Patient With an Abnormal Gait

Lim, Moe R.; Huang, Russel C.; Wu, Anita; Girardi, Federico P.; Cammisa, Frank P.

doi:10.5435/00124635-200702000-00005

Cited by 72 publications

(41 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the antalgic gait observed in MIA animals is seen clinically in OA patients 31 . Antalgic gait in humans may result from either acute or chronic pain, where the former is used to reduce pain and discomfort and the latter is a maladaptive response to long-term degenerative conditions like OA 32,33 . It is possible antalgic gaits could evolve in MMT+MCLT animals at later time points, associating with long-term degenerative changes in the MMT+MCLT knee.…”

Section: Discussionmentioning

confidence: 99%

Unique spatiotemporal and dynamic gait compensations in the rat monoiodoacetate injection and medial meniscus transection models of knee osteoarthritis

Jacobs

Dunnigan

Pires-Fernandes

et al. 2017

Osteoarthritis and Cartilage

View full text Add to dashboard Cite

Objective In rodent osteoarthritis models, behavioral changes are often subtle and require highly sensitive methods to detect these changes. Gait analysis is one assay that may provide sensitive, quantitative measurement of these behavioral changes1. To increase detection sensitivity of gait assessments relative to spatiotemporal gait collection alone, we combined our spatiotemporal and dynamic gait collection systems. Using this combined system, gait was assessed in the rat medial meniscus transection model and monoiodoacetate injection model of knee osteoarthritis. Design 36 male Lewis rats were separated into medial meniscus transection (n=8), medial collateral ligament transection (n=8), skin incision (n=4), monoiodoacetate injection (n=8), and saline injection (n=8) groups. After initiation of osteoarthritis, gait data were collected weekly in each group out to 4 weeks. Results The medial meniscus transection and monoiodoacetate injection models produced unique pathologic gait profiles, with medial meniscus transection animals developing a shuffling gait and monoiodoacetate injection animals exhibiting antalgic gait. Spatiotemporal changes were also observed in the medial meniscus transection model at week 1 (p<0.01), but were not observed in the monoiodoacetate injection model until week 3 (p<0.01). Dynamic gait changes were observed in both models as early as 1 week post-surgery (p<0.01). Conclusion Combined analysis of spatiotemporal and dynamic gait data increased detection sensitivity for gait modification in two rat osteoarthritis models. Analyzing the combined gait data provided a robust characterization of the pathologic gait produced by each model. Furthermore, this characterization revealed different patterns of gait compensations in two common rat models of knee osteoarthritis.

show abstract

Section: Discussionmentioning

confidence: 99%

Unique spatiotemporal and dynamic gait compensations in the rat monoiodoacetate injection and medial meniscus transection models of knee osteoarthritis

Jacobs

Dunnigan

Pires-Fernandes

et al. 2017

Osteoarthritis and Cartilage

View full text Add to dashboard Cite

show abstract

“…13,16 The severity in the restriction of range of motion and the location of a joint contracture determine the patient's functional limitations. Upper limb contractures impair tasks such as showering, dressing, feeding, hand to occiput and hand to perineum; 15,26 lower limb contractures affect ambulation 5,8,10,28,30 and increase the risk of falls. 30 Of the 39% of patients in our study who had any contractures, most (85%) had 1 or more contractures with severity that was considered functionally important.…”

Section: Discussionmentioning

confidence: 99%

Joint contracture following prolonged stay in the intensive care unit

Clavet¹,

Hébert²,

Fergusson³

et al. 2008

Canadian Medical Association Journal

155

102

View full text Add to dashboard Cite

“…Furthermore, specific gait-related abnormalities associated with CSM are poorly defined in the literature. 35 A more quantifiable method of gait assessment may have improved the diagnostic accuracy of our clustered model.…”

mentioning

confidence: 99%

Clustered clinical findings for diagnosis of cervical spine myelopathy

Cook¹,

Brown²,

Isaacs³

et al. 2010

Journal of Manual & Manipulative Therapy

View full text Add to dashboard Cite

Cervical spine myelopathy (CSM) is a clinical diagnosis made with imaging confirmation. At present, most clinical tests used to identify CSM are specific and no clusters of tests have proven more beneficial than stand alone tests in guiding treatment decision making. This study endeavored to produce a cluster of predictive clinical findings for a sample of patients using a clinical diagnosis/imaging confirmation as the reference standard for cervical spine myelopathy. Data from 249 patients with various conditions associated with cervical spine dysfunction were analyzed to determine which clinical tests and measures, when clustered together, were most diagnostic for CSM. Using multivariate regression analyses and calculations for sensitivity, specificity, and positive and negative likelihood ratios, a definitive cluster was identified. Thirteen clinical findings were investigated for capacity to diagnosis CSM. Five clinical: (1) gait deviation; (2) zHoffmann's test; (3) inverted supinator sign; (4) zBabinski test; and (5) age .45 years, were demonstrated the capacity when clustered into one of five positive tests to rule out CSM (negative likelihood ratio50.18; 95% CI50.12-0.42), and when clustered into three of five positive findings to rule in CSM (positive likelihood ratio530.9; 95% CI55.5-181.8). This study found clustered combinations of clinical findings that could rule in and rule out CSM. These clusters may be useful in identifying patients with this complex diagnosis in similar patient populations.

show abstract

Evaluation of the Elderly Patient With an Abnormal Gait

Cited by 72 publications

References 37 publications

Unique spatiotemporal and dynamic gait compensations in the rat monoiodoacetate injection and medial meniscus transection models of knee osteoarthritis

Unique spatiotemporal and dynamic gait compensations in the rat monoiodoacetate injection and medial meniscus transection models of knee osteoarthritis

Joint contracture following prolonged stay in the intensive care unit

Clustered clinical findings for diagnosis of cervical spine myelopathy

Contact Info

Product

Resources

About