Evaluation of the elasticity and characteristic impedance of the ascending aorta in man

Merillon, J. P.; Motté, G; Fruchaud, J; Masquet, C; Gourgon, R

doi:10.1093/cvr/12.7.401

Cited by 78 publications

(42 citation statements)

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“…Therefore, the PWV is proportional to the square root of Ep. It has been shown that Ep increases with pulse pressure, and the rate of increase is higher in older subjects compared to young subjects (2). The Ep estimated with our method is actually the average Ep over the whole range of pulse pressures.…”

Section: Discussionmentioning

confidence: 72%

“…The spatial-temporal profiles in both the presystolic (Eq. [2]) and early systolic (Eq. [3]) phases were fitted with a linear function by a least-squares algorithm:…”

Section: Calculation Of Pwvmentioning

confidence: 99%

“…[2] and [3], respectively. To determine the PWV we first defined a line intersecting the two fitted planes in the presystolic and early systolic phases (Fig.…”

Section: Calculation Of Pwvmentioning

confidence: 99%

“…The velocity of a pressure wave, which is called the pulse wave velocity (PWV), depends on the density of the blood, the cross-sectional area of the vessel lumen, and the compliance of the vessel wall (2,3). Many studies have found that the PWV is sensitive to degenerative or pathological changes to the vessel wall and the hemodynamic status (4 -6).…”

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confidence: 99%

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Quantification of the pulse wave velocity of the descending aorta using axial velocity profiles from phase‐contrast magnetic resonance imaging

Peng

Wang

et al. 2006

Magnetic Resonance in Med

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The pulse wave velocity (PWV) of aortic blood flow is considered a surrogate for aortic compliance. A new method using phase-contrast (PC)-MRI is presented whereby the spatial and temporal profiles of axial velocity along the descending aorta can be analyzed. Seventeen young healthy volunteers (the YH group), six older healthy volunteers (the OH group), and six patients with coronary artery disease (the CAD group) were studied. PC-MRI covering the whole descending aorta was acquired, with velocity gradients encoding the in-plane velocity. From the corrected axial flow velocity profiles, PWV was determined from the slope of an intersecting line between the presystolic and early systolic phases. Furthermore, the aortic elastic modulus (Ep) was derived from the ratio of the brachial pulse pressure to the strain of the aortic diameter. The PWV increased from YH to OH to CAD (541 ؎ 94, 808 ؎ 184, 1121 ؎ 218 cm/s, respectively; P ‫؍‬ 0.015 between YH and OH; P ‫؍‬ 0.023 between OH and CAD). There was a high correlation between PWV and Ep (r ‫؍‬ 0.861, P < 0.001). Multivariate analysis showed that age and CAD were independent risk factors for an increase in the PWV. Compared to existing methods, our method requires fewer assumptions and provides a more intuitive and objective way to estimate the PWV. Magn Reson Med 56:876 -883, 2006.

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Section: Discussionmentioning

confidence: 72%

“…The spatial-temporal profiles in both the presystolic (Eq. [2]) and early systolic (Eq. [3]) phases were fitted with a linear function by a least-squares algorithm:…”

Section: Calculation Of Pwvmentioning

confidence: 99%

“…[2] and [3], respectively. To determine the PWV we first defined a line intersecting the two fitted planes in the presystolic and early systolic phases (Fig.…”

Section: Calculation Of Pwvmentioning

confidence: 99%

mentioning

confidence: 99%

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Quantification of the pulse wave velocity of the descending aorta using axial velocity profiles from phase‐contrast magnetic resonance imaging

Peng

Wang

et al. 2006

Magnetic Resonance in Med

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“…However, human studies are limited for methodological reasons, principally because of the invasive nature of evaluation techniques. 6 Recent progress in noninvasive echo Doppler ultrasound has enabled more adequate evaluation of the viscoelastic properties of large arteries by using transcutaneous measurements in situ. 7 -12 The geometry and the mechanical properties of specific arterial segments may be investigated in situ, but such studies have yielded poor results in patients with hypertension.…”

Section: A Noninvasive Study Of Carotid and Femoral Arteriesmentioning

confidence: 99%

Arterial alterations with aging and high blood pressure. A noninvasive study of carotid and femoral arteries.

Bénétos

Laurent

Hoeks

et al. 1993

Arterioscler Thromb

514

325

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Noninvasive in situ evaluations of pulsatile changes of blood pressure and arterial diameter were performed at the sites of the common carotid and femoral arteries in a population of 78 untreated normotensive and hypertensive subjects. Arterial segments were studied by using an original echotracking technique for internal diameter and validated applanation tonometry for local pulse pressure measurements. Whereas mean arterial pressure is known to be identical in all parts of the arterial tree, pulse pressure was significantly lower in the carotid (52.7±2.2 mm Hg) than in the brachial (62.0±2.0 mm Hg) or femoral (62.5 ±2.5 mm Hg) arteries. Despite a higher pulse pressure and diastolic diameter, the femoral artery had a lower pulsatile change in diameter (3.47±0.18% versus 6.07+0.28%; p<0.0001) and distensibility coefficient (9.36±0.58 versus 21.60+1.75 xlO" 3 kPa" 1 ) than the carotid artery. Local cross-sectional compliance of the carotid artery was higher than that of the femoral artery (7.42±0.46 versus 6.20±0.28 m 2 • kPa" 1 • 10~7;p<0.05). Whereas age was strongly correlated with arterial parameters at the site of the carotid artery (pulse pressure: r=0.54, p<0.0001; pulsatile change in arterial diameter: r=-0.62, p<0.0001; distensibility coefficient: r=-0.70, p<0.0001), no significant correlation was observed at the femoral artery. Mean blood pressure was the second factor of carotid artery alterations: the higher the mean blood pressure, the lower the distensibility of this artery (r= -0.36, p<0.01). Since no atherosclerotic lesions were detected in the studied subjects, it is suggested that, for the same mean arterial pressure 1) the common carotid artery is exposed to lower pulse pressure than the common femoral artery, 2) the common carotid artery is a highly compliant artery with a strong alteration of its viscoelastic properties with age, and 3) the common femoral artery has smaller mechanical "buffering" properties than the carotid artery, with little influence by aging. This study provides evidence that the effects of aging and elevated blood pressure differ substantially in the different portions of the arterial tree. (Arteriosclerosis and Thrombosis 1993;13:90-97) KEY WORDS • pulsatile changes of arterial diameter • pulsatile changes of blood pressure • echo-tracking techniques • tonometry • hypertension • aging A Iterations of large arteries are a major factor of /\ cardiovascular morbidity and mortality. 1 Ag-X JL. ing, hypertension, and other risk factors such as diabetes, hyperlipidemia, and smoking can alter i:he structural and functional properties of the arterial wall. The principal changes that occur with aging are arterial dilation, increase in wall thickness, and decrease in elasticity and compliance. 2 It is well known that large arteries have not only a conduit but also a "buffering" function. 3 Because of their distensibility, they can dampen the pulsatile systolic output of the ventricle. Indeed, after left ventricular ejection has distended the aorta and its larger branches and ...

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Increase in aortic pulse wave velocity is associated with abnormal postprandial triglyceride response

et al. 2005

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SummaryBackground: Aortic pulse wave velocity (aPWV), an index of aortic distensibility, and postprandial hypertriglyceridemia are recognized as independent cardiovascular risk factors.Hypothesis: The aim of this study was to evaluate the relationship between postprandial hypertriglyceridemia and changes in aPWV.Methods: We prospectively studied 45 patients (mean age 48 [14] years, 28.9% men), who were submitted to a standardized fat meal (FM) test. According to their triglyceride (TG) levels 2, 4, 6, and 8 h after the FM, the patients were divided into two groups: Group 1 (31 patients) with postprandial TG levels ≤ 219 mg/dl, and Group 2 (14 patients) with TG levels > 219 mg/dl at one of the aforementioned time intervals. Before and 6 h after the FM, aPWV was measured noninvasively.Results: Baseline characteristics in the two groups were similar, except for higher TG, pulse pressure, waist-to-hip ratio, percentage of patients who smoked or had arterial hypertension, and lower high-density lipoprotein cholesterol levels in Group 2. Postprandially, aPWV was higher in Group 2 [11.2(2.7) vs. 9.1(2.1) m/s, p = 0.004]. Changes in aPWV correlated with TG changes from baseline to 6 h after FM (r = 0.539, p < 0.001) and with the areas under the TG curve (r = 0.617, p < 0.001). A postprandial TG increase of 100 mg/dl resulted in a 0.88 m/s rise of aPWV.

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Evaluation of the elasticity and characteristic impedance of the ascending aorta in man

Cited by 78 publications

References 0 publications

Quantification of the pulse wave velocity of the descending aorta using axial velocity profiles from phase‐contrast magnetic resonance imaging

Quantification of the pulse wave velocity of the descending aorta using axial velocity profiles from phase‐contrast magnetic resonance imaging

Arterial alterations with aging and high blood pressure. A noninvasive study of carotid and femoral arteries.

Increase in aortic pulse wave velocity is associated with abnormal postprandial triglyceride response

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