Evaluation of the Efficacy of Various Topical Fluorides on Enamel Demineralization Adjacent to Orthodontic Brackets: An In Vitro Study

Reddy, Rishika; Manne, Ranjit; Sekhar, G Chandra; Gupta, Sumit; Shivaram, Nemani; Nandalur, Kulashekar R

doi:10.5005/jp-journals-10024-2481

Cited by 8 publications

(7 citation statements)

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“…After a full-text examination, six articles were rejected due to not meeting the inclusion criteria. Finally, 17 articles qualified for the systematic review [8,12,24,25,[34][35][36][37][38][39][40][41][42][43][44][45][46]. All of the included studies were written in English and were either in vitro or in vivo studies.…”

Section: Study Selectionmentioning

confidence: 99%

“…Both studies found that the addition of a fluorine compound did not affect the whitening properties but did increase tissue remineralization [40,42]. Reddy et al demonstrated remineralization of enamel on extracted premolars after the application of 1.23% APF gel [43].…”

Section: General Characteristics Of the Included Studiesmentioning

confidence: 99%

“…Seven studies [24,35,37,39,40,42,43] demonstrated the effect of fluoride gel on the tissue surface of human or bovine teeth, all of which showed increased surface remineralization. Three articles [8,25,34] also demonstrated the effect of fluoride gel on the surface of stainless steel and titanium alloys, with defects observed in all cases.…”

Section: Main Study Outcomesmentioning

confidence: 99%

“…Out of seventeen articles, ten were assigned with a low risk of bias [34,35,[37][38][39][40]42,43,45,46], six with a moderate risk of bias [8,12,25,36,41,44], and one with a high risk of bias [24]. The results of the performed Quality Assessment are presented in Table 2.…”

Section: Quality Assessmentmentioning

confidence: 99%

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The Influence of Fluoride Gels on the Physicochemical Properties of Tooth Tissues and Dental Materials—A Systematic Review

Piszko,

Kiryk

et al. 2024

Gels

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The aim of the presented systematic review is to update the state of knowledge and relate the properties and composition of fluoride gels to their potential application. This article aims to explore the effect of fluoride gel application on changes in the properties of dental biomaterials and tooth tissues. The review includes articles assessing studies on the effects of fluoride gel on dental tissues and materials. Employing the PRISMA protocol, a meticulous search was conducted across the PubMed, Scopus, and Web of Science databases, utilizing keywords such as fluoride, gel, and properties. The publications were selected without limitation by the year of publication, and then Cohen’s κ test was used to assess the agreement of the respondents. Exclusion criteria included non-English studies, opinion pieces, editorial papers, letters to the editor, review articles and meta-analyses, clinical reports, studies lacking full-text accessibility, and duplicates. The quality of the chosen papers was assessed by two independent reviewers. A total of 2385 were located in databases, of which only 17 met the inclusion criteria. All publications showed increased surface mineralization, and seven studies showed the effect of fluoride gel on the surface of dental tissues. Three articles stated a negative effect of fluoride gels on titanium and stainless steel alloys and glass ionomer fillings. The effects on shear bond strength and plaque deposition require further investigation because the study results are contradictory.

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Section: Study Selectionmentioning

confidence: 99%

Section: General Characteristics Of the Included Studiesmentioning

confidence: 99%

Section: Main Study Outcomesmentioning

confidence: 99%

Section: Quality Assessmentmentioning

confidence: 99%

See 2 more Smart Citations

The Influence of Fluoride Gels on the Physicochemical Properties of Tooth Tissues and Dental Materials—A Systematic Review

Piszko,

Kiryk

et al. 2024

Gels

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“…Remineralization can be achieved with agents such as fluoride, which is administered through gels, toothpaste, and mouthwashes 3,4 . However, it has been reported that chronic exposure to low fluoride levels can have toxic effects on systemic health 5 .…”

Section: Introductionmentioning

confidence: 99%

Effects of Homemade Nano-Hydroxyapatite and Olive Oil Paste on Remineralization of Early Caries Lesions

et al. 2022

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Nano-hydroxyapatite (nHAP) particles are a new generation of materials reported to remineralize enamel lesions. The purpose we aimed was to compare the in vitro effects of fluoride gel, sodium fluoride toothpaste, and homemade nHAP paste on remineralizing artificial early enamel caries. Methods: Incipient caries were induced in 21 extracted, sound premolar teeth by storing each specimen in a demineralization solution for 72 hours, followed by pH cycling. The samples (n= 7, each) were then treated with 2% neutral fluoride gel, 0.25% sodium fluoride toothpaste, or homemade nHAP paste, comprising a mixture of nHAP powder and olive oil. After demineralization and remineralization, the results were compared using the DIAGNOdent pen (KaVo, Germany). The data were statistically analyzed using paired t-tests and a one-way ANOVA test. Outcomes: The degree of demineralization in each of the three groups (fluoride gel group, 15.71; sodium fluoride dentifrice group, 15.28; nHAP paste group, 16.71) was significantly elevated compared to baseline (3, 2.5, 2.28, respectively); however, no significant difference was observed between the remineralization readings in each of the three groups (6, 7, 5.5, respectively) (p > 0.05). In conclusion, we concluded that the homemade nHAP paste had a beneficial effect on the remineralization of initial enamel caries lesions.

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Binder‐Loaded Amorphous Nanometer Calcium Phosphate in Preventing Enamel Demineralization in Orthodontic Patients

Gao¹,

Dang

Zhang³

et al. 2022

Journal of Nanomaterials

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With the popularization of oral health knowledge, people have gradually realized the importance of orthodontic treatment in oral health, so the number of patients undergoing orthodontic treatment has increased significantly. To improve the effect of orthodontic treatment, this article mainly studied the application of adhesives loaded with amorphous nanocalcium phosphate in the prevention of enamel demineralization in orthodontic patients. In the experiment, we used spray-drying technology to synthesize NACP. The collected dry particles were dispersed with absolute ethanol, sonicated for 10 minutes, dropped on a 200 ordinary carbon support film, and then dried and observed with a transmission electron microscope (TEM). Prevention of enamel demineralization in orthodontic patients was by adhesive-loaded amorphous nanocalcium phosphate. In this experiment, the membrane dialysis method was used to release the drug-loaded nanoparticles. The MH-5 microhardness tester was used to randomly select 3 positions on the buccal area of the enamel surface to measure the microhardness. After measuring the microhardness of each point, take the average of the readings of the 3 positions. Before and after the experiment, the difference of the enamel surface microhardness before and after the experiment was statistically analyzed. Before the scanning electron microscope observation, to avoid contamination of the window area of the enamel surface, which will cause interference with the scanning electron microscope observation, we use acetone to remove the acid-resistant nail polish coated on the enamel surface. Clean the attachments on the surface of the teeth first, then fix, dehydrate, and dry. When the release time reaches 52 h, the cumulative release rates of Cur in pH 5.4 and pH 7.4 buffers are 85.84 and 64.68%, respectively. The results show that by adjusting the concentration of PAA, it is possible to configure a mineralized liquid that can not only use the fluidity of NACP to penetrate into the collagen fibers but also transform into HAP within a suitable time, to achieve the purpose of repairing demineralized dentin.

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Evaluation of the Efficacy of Various Topical Fluorides on Enamel Demineralization Adjacent to Orthodontic Brackets: An In Vitro Study

Cited by 8 publications

References 0 publications

The Influence of Fluoride Gels on the Physicochemical Properties of Tooth Tissues and Dental Materials—A Systematic Review

The Influence of Fluoride Gels on the Physicochemical Properties of Tooth Tissues and Dental Materials—A Systematic Review

Effects of Homemade Nano-Hydroxyapatite and Olive Oil Paste on Remineralization of Early Caries Lesions

Binder‐Loaded Amorphous Nanometer Calcium Phosphate in Preventing Enamel Demineralization in Orthodontic Patients

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