Evaluation of The Effects of Vitamin C on Epithelialization of Burn Wounds

Abstract

Objectives: The purpose of the present study is to determine the effect of topical vitamin C on second degree burn wounds restoration. This was a clinical trial. The sample size was determined as 30. The participants were selected from the patients suffering from second degree burns who visited the Burn Center of Vaseei Hospital in Sabzevar. Both intervention and control groups targeted one patient. Dressing was changed in a daily manner after cleansing. Topical vitamin C solution was administered on the wounds. The Bates-Jensen Wound Assessment Tool was used to evaluate burn wound parameters in the 1st, 3rd, 7th and 14th day of treatment. Data analysis was performed using SPSS v.16 and ‘’repeated measures ANOVA.Results: The average age of participants was 43.33 ± 11.9 years and 60% of the participants were males and 40% of them were females. The results of repeated measures ANOVA showed a statistically significant difference in mean scores of wound between the two treatments (P = 0.047), wound healing significantly differed in the two groups and topical vitamin C solution had a significant effect on acceleration of wound Epithelialization. According to the results of this study, administration of topical vitamin C is recommended for epithetlialization of second degree burns.IRCT: IRCT2015101224487N1