Evaluation of the Effect of Long-term Use of Three Intracanal Medicaments on the Radicular Dentin Microhardness and Fracture Resistance: An in vitro study

Amonkar, Ankita Dilip; Dhaded, Neha; Kore, Preeti; Patil, Anand C; Hugar, Shivayogi M; Bhandi, Shilpa; Raj, A. Thirumal; Patil, Shankargouda; Zanza, Alessio; Testarelli, Luca

doi:10.15644/asc55/3/6

Cited by 13 publications

(9 citation statements)

References 37 publications

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“…Regarding the period of time, there was a statistically significant decrease in mean microhardness in dentin samples posttreatment, which may be related to the mixed acids present in case of antibiotic pastes, that are important to regulate their tonicity and to preserve the chemical steadiness of the antibiotic pastes. 14,28 This result was in agreement with Amonkar et al 29 who stated that the exposure time is directly proportional to dentin demineralization, considering time an important factor when using intracanal medicament. Also, Bahandi et al stated that using intracanal medicament for a period of time less than 24 hours can be well tolerated with harmful effects on samples.…”

Section: B Statistical Analysissupporting

confidence: 87%

Effect of Nano Forms of Propolis and Antibiotic Pastes as canal Medicaments on Radicular Dentin Microhardness. (In-Vitro Study)

Mohamed

Gendy²,

Bayoumi³

2022

Journal of Fundamental and Clinical Research

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Background:In order to increase affected tooth' life span, a successful endodontic treatment is required. Although mechanical preparation and proper irrigation play an important role in root canal treatment's success rate, yet application of intracanal medicament is still a major key in obtaining an endodontically favourable outcome. Objectives: to asses the change in dentin microhardness after the use of Nano-Propolis, Double Antibiotic Paste (DAP) and Triple Antibiotic Paste (TAP) as an intracanal medicament by Vickers Test. Materials and Methods: Forty-two extracted human single rooted lower premolars were collected and longitudinally sectioned in a bucco-lingual direction into two halves using a low-speed saw with a diamond disc. One half received the canal medicament while the other half was used as a control for dentin microhardness measurements. Teeth were divided into 3 different experimental groups equally according to the type of testing material; Propolis, Double and Triple Antibiotic Paste. Each group was further divided into 2 equal subgroups (7 each) according to the used medicament particle size either nano or micro sized. After two weeks, the difference between Propolis, DAP and TAP in nano and micro forms was investigated by Vicker's test to evaluate the micro-hardness. Results: A statistically significant difference was found in the median % reduction in radicular dentin microhardness. Conclusion:DAP, Nano TAP, Propolis, Nano DAP and TAP when used as intracanal medicaments adversely affects radicular dentin microhardness percentage reduction respectively, while Nano Propolis is considered safe as intracanal medicament regarding microhardness percentage reduction of root canal dentin.

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Section: B Statistical Analysissupporting

confidence: 87%

Effect of Nano Forms of Propolis and Antibiotic Pastes as canal Medicaments on Radicular Dentin Microhardness. (In-Vitro Study)

Mohamed

Gendy²,

Bayoumi³

2022

Journal of Fundamental and Clinical Research

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“…Triple antibiotic paste (TAP), consisting of equal portions of metronidazole, ciprofloxacin and minocycline, and double antibiotic paste (DAP), obtained by removing minocycline from triple antibiotic paste, are the most commonly used antibiotic pastes. However, antibiotic pastes can cause discoloration of dentin [10], and CH has a negative effect on the physical properties of radicular dentin [11]. Moreover, these medicaments cannot be removed from the root canal entirely [10,12].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the removal of 2‐Hydroxyisocaproic acid from the root canal and its effect on the bond strength of MTA

2022

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This study aimed to evaluate the removal of 2‐hydroxyisocaproic acid (HICA) from the root canal system and its effect on the bond strength of the mineral trioxide aggregate (MTA). 126 single‐rooted teeth were divided into 3 experimental groups (n = 36) that were treated with double antibiotic paste (DAP), HICA and calcium hydroxide (CH) and one control group (n = 18). In the first part, 18 teeth from each experimental group (n = 54) were examined to remove HICA from the root canal. In the second part, 72 teeth (3 experimental groups (n = 54) and one control group (n = 18)) were used for the evaluation of the push‐out bond strength of MTA. There was no statistically significant difference between HICA, DAP and CH residues (p > 0.05). HICA group showed significantly less push‐out bond strength (p < 0.05). DAP, HICA and CH could not be removed entirely from the root canal. HICA significantly reduced the bond strength of the MTA.

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“…According to them, CH reduces dentine microhardness over time, which can be countered by the addition of activated charcoal. Amonkar et al [ 29 ] also reported that long-term application of CH significantly reduces dentine microhardness. A study by Parashar et al [ 30 ] also reported a significant reduction in microhardness values after CH.…”

Section: Discussionmentioning

confidence: 99%

Effect of Propolis on Root Dentine Microhardness When Used as an Intracanal Medicament: An In Vitro Study

Naeem

Sarwar

Nisar

et al. 2023

JFB

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Application of intracanal medicaments may affect the physical properties of root dentine. Calcium hydroxide (CH), a gold standard intracanal medicament, has proven to decrease root dentine microhardness. A natural extract, propolis, has been shown to be superior to CH in eradicating endodontic microbes, but its effect on the microhardness of root dentine is still not known. This investigation aims to evaluate the effect of propolis on root dentine microhardness compared to calcium hydroxide. Ninety root discs were randomly divided into three groups and treated with CH, propolis, and a control. A Vickers hardness indentation machine with a load of 200 g and dwell time of 15 s at 24 h, 3, and 7 days was used for microhardness testing. ANOVA and Tukey’s post hoc test were used for statistical analysis. A progressive decrease in microhardness values was observed in CH (p < 0.01), whereas a progressive increase was observed in the propolis group (p < 0.01). At 7 days, propolis demonstrated the highest microhardness value (64.43 ± 1.69), whereas CH demonstrated the lowest value (48.46 ± 1.60). The root dentine microhardness increased over time when propolis was applied, while it decreased over time after application of CH on root dentine sections.

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Evaluation of the Effect of Long-term Use of Three Intracanal Medicaments on the Radicular Dentin Microhardness and Fracture Resistance: An in vitro study

Cited by 13 publications

References 37 publications

Effect of Nano Forms of Propolis and Antibiotic Pastes as canal Medicaments on Radicular Dentin Microhardness. (In-Vitro Study)

Effect of Nano Forms of Propolis and Antibiotic Pastes as canal Medicaments on Radicular Dentin Microhardness. (In-Vitro Study)

Evaluation of the removal of 2‐Hydroxyisocaproic acid from the root canal and its effect on the bond strength of MTA

Effect of Propolis on Root Dentine Microhardness When Used as an Intracanal Medicament: An In Vitro Study

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