Abstract:Objective: was directed to evaluate platelet rich fibrin alone and in combination with xenograft as an alternative to bone substitute in treatment of critical sized bone defects in dogs. Subjects and methods: 8 dogs were selected for this study in which diabetes mellitus was induced. Root canal treatment was done in the 2 nd and 4 th premolar teeth of both sides then 4 critical sized bone defects were created in relation to the distal root of the selected teeth. According to the bone cavity filling materials t… Show more
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