Evaluation of the Effect of Casein Phosphopeptide–Amorphous Calcium Phosphate Mousse versus Natural Raw Fresh Milk on Enamel Surface Roughness After a pH Challenge

Al-Ani, Safa; Al-Naimi, Raya

doi:10.33899/rden.2020.127159.1033

Cited by 5 publications

(4 citation statements)

References 15 publications

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“…A recent study by Al-Ani and Al-Naimi concluded that CCP-ACP tooth mousse, raw fresh buffalo, and cow milk were all effective remineralizing agents, reducing the enamel surface roughness after a pH challenge. 33 They however, in contrast to our findings, stated that CCP–ACP tooth mousse showed more superior results.…”

Section: Discussioncontrasting

confidence: 99%

Remineralizing Potential of Milk and GC Tooth Mousse on Demineralized Human Enamel: An In Vitro Comparative Evaluation

Shetty

Bhandary

Vakil

2022

Journal of Health and Allied Sciences NU

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Introduction Caries initiation is associated with demineralization of the subsurface tooth enamel. Today, bioactive agents based on milk products have been developed to enhance remineralization under cariogenic conditions. However, there is limited information on the remineralization potential of milk. Materials and Methods Fifty enamel specimens were prepared from sound human premolars. All enamel specimens were then placed in demineralizing solution for 4 days at 37°C to produce artificial carious lesion. Baseline surface microhardness (SMH) was evaluated using Vickers indenter. Enamel specimens were then randomly divided into three groups. Group 1 specimens were kept in artificial saliva, whereas group 2 and 3 enamel specimens were treated with milk and GC tooth mousse, respectively, for 5 minutes twice daily for 21 days. Post-treatment SMH measurements of all specimens were evaluated on the 7th, 14th, and 21st day. Data was statistically analyzed using one-way analysis of variance test and Tukey honest significant difference post-hoc test. Results There were no significant differences in the SMH values in the control group at any time interval. There were statistically significant increases in the post-SMH values in milk and GC tooth mousse (p < 0.001) at the end of 21st day of remineralization. Conclusion Milk showed remineralization potential comparable to that of GC tooth mousse.

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Section: Discussioncontrasting

confidence: 99%

Remineralizing Potential of Milk and GC Tooth Mousse on Demineralized Human Enamel: An In Vitro Comparative Evaluation

Shetty

Bhandary

Vakil

2022

Journal of Health and Allied Sciences NU

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“…This could be due to their nature that enables calcium and phosphate ions to be released from the remineralizing agent to infiltrate and diffuse surface and subsurface enamel porosities, 25 reduce the lesion depth, improve surface roughness and promote enamel remineralization. 26 These results agree with Al-Ani et al, 28 who concluded that CPP−ACP tooth mousse improved roughness significantly after pH cycling of enamel. Specimens treated with nanohydroxyapatite (Nano P) has a smother surface than CPP-ACFP.…”

Section: Discussionsupporting

confidence: 86%

Evaluation of Mechanical, Optical and Surface Changes of Pretreated Enamel Surface Bonded to Orthodontic Bracket Using Different Remineralizing Agents

2021

Mansoura Journal of Dentistry

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Objective: This study aimed to evaluate the effect of CPP-ACP, CPP-ACPF and nano-hydroxyapatite on enamel remineralization during fixed Orthodontic treatment. The treated specimens with different remineralizing agents were compared with their untreated and demineralized ones regarding surface roughness, surface microhardness, and color measurement. Materials and methods: A total number of 120 specimens from extracted orthodontic patient teeth was collected and divided into 4 equal groups (10 specimens each) according to the enamel surface treatment applied immediately after PH cycling; group A received no surface treatment and served as a control group. In group B, the enamel surface was treated by CPP-ACP, while group C enamel surface was treated by CPP-ACFP, and group D was treated by Desensibilize NanoP. The surface roughness was obtained using surface Profilometer and Vickers microhardness was measured using Digital Display Vickers Microhardness Tester. Evaluation for each specimen was performed before, after pH cycling and after using different remineralizing agents. The color change was analyzed for each specimen in different groups under the Spectrophotometer. The change in color from control specimens compared to the color of the demineralized specimens (ΔE 1 ), the difference in color between control specimens and after remineralization (ΔE 2 ) and the change in color between demineralized and remineralized specimens (ΔE 3 ) were calculated. The results were then statistically analyzed and compared using ANOVA and LSD test at level of significance 0.05. Results: The use of CPP-ACP, CCP-ACFP and NanoP significantly improved surface roughness, surface microhardness especially with NanoP with non-significant difference between the three remineralizing materials. NanoP exhibited the lowest change in color compared with CPP-ACFP and CPP-ACP paste. Conclusion:The use of CPP-ACP, CPP-ACFP and NanoP could be used as preventive materials during orthodontic treatment and be effective in repairing the demineralized enamel restoring its surface smoothness, hardness, and color.

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“…The solution of demineralization contains “0.075 mM/L acetic acid, 1 mM/L calcium chloride, and 2 mM/L potassium phosphate” and the pH will be adjusted to 4.3. Whereas the solution of remineralization, which contains “150 mM/L potassium chloride, 1.5 mM/L calcium nitrate, and 0.9 mM/L potassium phosphate” and the pH will be adjusted to 7 [ 10 ].…”

Section: Methodsmentioning

confidence: 99%

“…To simulate acidic challenge in a daily manner inside the environment of the mouth, crown samples were soaked in a demineralization solution for six hours, then were rinsed with distilled water for (1 minute) and then immersed in the prepared remineralizing agent for 17 hours. These steps were repeated once per day for 10 days [ 10 ]. The demineralizing and remineralizing solutions were refreshed daily.…”

Section: Methodsmentioning

confidence: 99%

Effect of Oral Vitamin D3 on Dental Caries: An In-Vivo and In-Vitro Study

Al-Jubori¹,

AL-Murad²,

Al-Mashhadane³

2022

Cureus

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Aim Vitamin D3 plays an important role in affecting the overall remineralization process of the dentition. The use of supplements help to keep the levels at optimum and thus reduce the chances of treating very early lesion of caries. Hence the aim was to investigate the indirect effects of oral vitamin D3 on microhardness and elemental weight percentage of Calcium (Ca) and Phosphorous (P) in enamel surface with an artificially initiated carious lesion. Methods The 120 extracted premolars were randomly divided into five groups according to salivary immersion. Each group had a total of twenty-four participants, with the following characteristics: control +ve: sound enamel; control -ve: only subjected to pH cycle; A: pH cycle and immersion in control saliva; B: pH cycle and saliva collected after three weeks; and C: pH cycle and saliva collected after six weeks. The unstimulated saliva was collected from (40) adult volunteers receiving vitamin D3 1000IU gel capsules daily for six weeks. Before each vitamin D3 intake, 10 mL of unstimulated control saliva was collected from each participant. Then other 10 ml. were collected after three and six weeks of vitamin D receiving periods. Saliva immersion time (12 hours). Enamel surface was assessed by Vicker’s Microhardness machine and (X-ray fluorescence - XRF) spectrometer. Results For all specimens, there was a significant decrease in both (Ca and P weight %) after demineralization and then they significantly increased after receiving vitamin D3. The microhardness and elemental analysis provide confirmed results that were represented as a statistically significant difference at (P≤ 0.05) between groups that received vitamin D3 and those without vitamin D3 dosage. Conclusions Oral vitamin D3 has a significant potential in motivating remineralization of early lesions on the enamel surfaces representing improved surface microhardness and minerals content (Ca and P weight %) of demineralized tooth surfaces.

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Evaluation of the Effect of Casein Phosphopeptide–Amorphous Calcium Phosphate Mousse versus Natural Raw Fresh Milk on Enamel Surface Roughness After a pH Challenge

Cited by 5 publications

References 15 publications

Remineralizing Potential of Milk and GC Tooth Mousse on Demineralized Human Enamel: An In Vitro Comparative Evaluation

Remineralizing Potential of Milk and GC Tooth Mousse on Demineralized Human Enamel: An In Vitro Comparative Evaluation

Evaluation of Mechanical, Optical and Surface Changes of Pretreated Enamel Surface Bonded to Orthodontic Bracket Using Different Remineralizing Agents

Effect of Oral Vitamin D3 on Dental Caries: An In-Vivo and In-Vitro Study

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