Evaluation of the Digital Rectal Examination as a Screening Test for Prostate Cancer

Abstract

For PSA values of 0-3.9 ng/mL, the positive predictive value and sensitivity of DRE, tumor volume, and tumor grade were strongly dependent on PSA level. DRE has a poor performance in low PSA ranges.

Major impact of hormonal therapy in localized prostate cancer—death can already be an exception

“…The same conclusion of the high efficacy of PSA has been reached in two other large scale screening studies [66][67][68]. A similar conclusion has been reached by Hugosson et al [69] who wrote: "PSA seems to be excellent as a prescreening test to identify the population at risk and which needs further evaluation [70,71]".…”

The Accuracy of Clinical Examination in the Diagnosis of Rectal Intussusception

“…8 Clinical examinations in several other conditions in the perineum, such as anorectal abscesses and fistulas, as well as urological diseases also have been compared with other investigations such as magnetic resonance imaging or ultrasound. [17][18][19] These data tell that a well-performed clinical examination can reach far but that you get some extra information from further investigations.…”

Dépistage du cancer de la prostate dans la population générale: des inconvénients certains, un bénéfice hypothétique

“…Le toucher rectal n'est pas utilisé seul car il est peu sensible, il est en effet anormal chez moins de 40 % des patients ayant un cancer (37 % dans [14], 39 % dans [15]). Dans les études de dépistage, il est utilisé en complément au dosage du PSA d'une façon variable dans les différents pays : systématiquement dans certains pays, et en fonction du niveau du PSA dans d'autres.…”