Evaluation of the Cancer Transition Theory in the US, Select European Nations, and Japan by Investigating Mortality of Infectious- and Noninfectious-Related Cancers, 1950-2018

Gersten, Omer; Barbiéri, Magali

doi:10.1001/jamanetworkopen.2021.5322

Cited by 9 publications

(18 citation statements)

References 85 publications

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“…Cancer is a major public health problem worldwide and the leading cause of death in developed and developing countries (Ferlay et al, 2018). Moreover, cancer incidence and mortality are quickly growing worldwide for different reasons, including aging, population growth and socioeconomic development (Gersten and Barbieri, 2021). Cancer is uncontrolled cell growth caused by several genetic and epigenetic changes in genes that control cell proliferation or regulate cell death (Garcia-Oliveira et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

The Synergistic Anticancer Effect of Some Plant Extracts in Combination against Human Liver Cancer Cell Line

Moatasem¹,

Dhifaf²,

Emaduldeen³

et al. 2023

AJDFR

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Background: Cancer is still a major health problem worldwide, despite the big development in treatment and diagnostic methods. For this reason, this study aims to find new drugs with low cost and fewer side effects on cancer cells continue. Medical plants represent a suitable candidate for discovering new materials for cancer treatment. Methods: Ten plants usually used in traditional medicine were used to evaluate their effectiveness as anti-cancer. These plants were divided into two mixtures according to traditional usage, named mixtures A and B. The anticancer effect against HepG2 was determined by MTT assay. The IC50 was also calculated. Result: Mixture A showed cytotoxicity reached 66.98%, while mixture B showed 63.66% by using 400 µg/ml at 4 8h. The IC50 for mixture A was 53 µg/ml, while for mixture B was 44.29 g/ml. All these results compare to normal cell line HnFd cells. In conclusion, mixing medical plants can effectively increase the anticancer activity of the synergistic effect between the phytochemicals. Future studies will be done to scan these effects.

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Section: Introductionmentioning

confidence: 99%

The Synergistic Anticancer Effect of Some Plant Extracts in Combination against Human Liver Cancer Cell Line

Moatasem¹,

Dhifaf²,

Emaduldeen³

et al. 2023

AJDFR

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“…According to recent cancer statistics, 247,952 new cancers and 83,776 cancer-related deaths occurred in Korea in 2020 [3]. Furthermore, cancer incidence and death rates are increasing worldwide, and the burden of disease is rapidly increasing [4,5]. These increases are related to changes in…”

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confidence: 99%

Epidemiology of Urologic Cancer in Korea: Nationwide Trends in the Last 2 Decades

Han

Yuk

2023

Korean J Urol Oncol

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Purpose: This study assessed recent trends in the incidence of urologic cancer and patient survival in Korea.Materials and Methods: The incidence of urologic cancer in Korea was calculated based on the Korea National Cancer Incidence Database and the South Korean Statistical Information Service Database. Data from 2000 to 2020 were used to determine the incidence, death, prevalence, and survival rates of urologic cancer.Results: Urologic cancer was diagnosed in 27,514 cases, accounting for 11.1% of the total cancer incidence. In 2020, there were 16,815 prostate cancer cases, 5,946 kidney cancer cases, and 4,753 bladder cancer cases. The age-standardized rate (ASR) for the incidence of prostate, kidney, and bladder cancer increased from 2000 to 2020. The overall ASR was 56 per 100,000 in 2020. In 2000, the ASRs for prostate, kidney, and bladder cancer were 2.9, 3.1, and 4.8 per 100,000, respectively, whereas they were 32.7, 11.6, and 9.3 per 100,000, respectively, in 2020. Urologic cancer has also seen a steady increase in the death rate, prevalence rate, and relative survival rate over the past 20 years. The 5-year relative survival rates for patients diagnosed with prostate cancer, kidney cancer, and bladder cancer during the 5-year period from 2015 to 2019 were 94.4%, 84.7%, and 76.5%, respectively. Among urologic cancers, prostate cancer had the highest survival rate, and bladder cancer had the lowest.Conclusions: The survival rate for urologic cancer is increasing; however, the incidence and prevalence rates continue to rise.

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“…According to the World Health Organization, cancer has become the first or second leading cause of death in people below 70 years in 112 out of 183 countries and ranked third or fourth in 23 more countries in 2019 [2]. Worldwide, the burden of cancer incidence and mortality is growing due to population aging and growth and the changes in the prevalence and distribution of major cancer risk factors, including those related to socioeconomic development [3,4].…”

mentioning

confidence: 99%

Prostate Cancer Epidemiology in the East Kazakhstan Region, 2010-2019

UMURZAKOV

Kaidarova

Shalgumbayeva

et al. 2022

Onkol. radiol. Kaz.

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Relevance: From 2010 to 2019, prostate cancer morbidity increased, and prostate cancer mortality decreased in Kazakhstan. The peak incidence was observed in patients aged 70 years and older. The East Kazakhstan region had higher morbidity and mortality from prostate cancer than the national average. The study aimed to: assess the indicators of prostate cancer epidemiology in the East Kazakhstan region from 2010 to 2019. Methods: The study calculated prostate cancer incidence, mortality, one-year and five-year survival, and early detection from 2010 to 2019. The statistical significance was assessed by the one-factor linear regression method. Intensive epidemiological indicators were calculated per 100 000 male population. Results: The prostate cancer incidence in East Kazakhstan increased from 2010 to 2019, while the mortality rate increased slightly. There was a statistically significant upward trend for morbidity (p=0.009) and a statistically insignificant trend for mortality (p=0.900). The one-year survival with prostate cancer tended to decrease. However, the trend of one-year survival rates had no statistical significance (p=0.202). The five-year survival rate of patients with prostate cancer in the East Kazakhstan region during the study period tended to decrease. However, the trend in the five-year survival rates of patients with prostate cancer in the East Kazakhstan region had no statistical significance (p=0.826). Early detection of prostate cancer in the early stages remained sustainable in the range of 72.7-77.4. In 2019, this indicator decreased to 63.2%. The share of prostate cancer cases detected at stage III tended to increase. The proportion of prostate cancer cases detected at stage IV tended to decrease during the study period. Conclusion: The prostate cancer epidemiological rates in East Kazakhstan were unstable in the study period. The incidence tended to increase; the mortality rate fluctuated within small limits and remained sustainable. The one-year survival rate tended to decrease. The five-year survival rate was slightly increasing. There was an increase in the detection of prostate cancer at stage III, while the detection at stage IV tended to decrease. Early detection of prostate cancer has decreased with an increase in detection at stage III. The proportion of prostate cancer cases detected at stage IV in the study period tended to decrease.

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Evaluation of the Cancer Transition Theory in the US, Select European Nations, and Japan by Investigating Mortality of Infectious- and Noninfectious-Related Cancers, 1950-2018

Cited by 9 publications

References 85 publications

The Synergistic Anticancer Effect of Some Plant Extracts in Combination against Human Liver Cancer Cell Line

The Synergistic Anticancer Effect of Some Plant Extracts in Combination against Human Liver Cancer Cell Line

Epidemiology of Urologic Cancer in Korea: Nationwide Trends in the Last 2 Decades

Prostate Cancer Epidemiology in the East Kazakhstan Region, 2010-2019

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