Evaluation of the Acceptance Rate of Covid-19 Vaccine and its Associated Factors: A Systematic Review and Meta-analysis

Kazeminia, Mohsen; Afshar, Zeinab Mohseni; Rajati, Mojgan; Saeedi, Anahita; Rajati, Fatemeh

doi:10.1007/s10935-022-00684-1

Cited by 18 publications

(20 citation statements)

References 128 publications

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“…Various studies have tried to evaluate attitude and willingness toward the COVID‐19 vaccine. In total, attitude toward vaccination against COVID‐19 among Iranian has been reported positive regardless of the vaccine type, from about 70% acceptance rate to more than 80% acceptance rate, which is slightly more than the global willingness 23–27 . Reportedly, misinformation and lack of knowledge contribute to hesitancy and negative attitudes toward COVID‐19 vaccination 23,28,29 …”

Section: Introductionmentioning

confidence: 99%

“…In total, attitude toward vaccination against COVID-19 among Iranian has been reported positive regardless of the vaccine type, from about 70% acceptance rate to more than 80% acceptance rate, which is slightly more than the global willingness. [23][24][25][26][27] Reportedly, misinformation and lack of knowledge contribute to hesitancy and negative attitudes toward COVID-19 vaccination. 23,28,29 Due to the extensive mortality of COVID-19, the health authorities approved emergency administration of the COVID-19 vaccines worldwide.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Evaluation of response to different COVID‐19 vaccines in vaccinated healthcare workers in a single center in Iran

Pourakbari

Mirbeyk

Mahmoudi

et al. 2022

Journal of Medical Virology

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Due to the recent coronavirus disease 2019 (COVID-19) pandemic and emergent administration of various vaccines worldwide, comprehensive studies on the different aspects of vaccines are in demand. This study evaluated antibody response after the second dose of the COVID-19 vaccine in the Children's Medical Center personnel. The blood samples of 174 healthcare workers were gathered at least 10 days after vaccination. The administered vaccines included Oxford/AstraZeneca, COVAXIN, Sinopharm, and Sputnik V. This study assessed all antibodies employing ELISA methods, including anti-SARS-CoV-2 neutralizing antibody by DiaZist and Pishtazteb kits, anti-SARS-CoV-2-nucleocapsid by Pishtazteb kit, and anti-SARS-CoV-2-Spike by Razi kit. The cutoff for the tests' results was calculated according to the instructions of each kit. Totally, 174 individuals with an average age of 40 ± 9years participated in this study, the proportion of men was 31%, and the frequency of past COVID-19 infection was 66 (38%). Sixteen (9%) personnel received Oxford/AstraZeneca, 28 (16%) COVAXIN, 29 (17%) Sinopharm, and 101 (58%) Sputnik V. anti-SARS-CoV-2-nucleocapsid and anti-SARS-CoV-2-Spike were positive in 37 (21%), and 163 (94%) participants and their mean level were more in adenoviral-vectored vaccines (p value < 0.0001). Neutralizing antibody was positive in 74% using Pishtazteb kit while 87% using DiaZist kit. All antibodies' levels were significantly higher in those with a past COVID-19 infection (p value < 0.0001). In conclusion, Oxford/AstraZeneca and Sputnik V had a similar outcome of inducing high levels of anti-SARS-Cov-2-spike and neutralizing antibodies, which were more than Sinopharm and COVAXIN. The titers of Anti-SARS-CoV-2-nucleocapsid antibody were low in all of these four vaccines.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Evaluation of response to different COVID‐19 vaccines in vaccinated healthcare workers in a single center in Iran

Pourakbari

Mirbeyk

Mahmoudi

et al. 2022

Journal of Medical Virology

View full text Add to dashboard Cite

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“…The vaccination status is determined by the plethora of complex factors. The COVID-19 vaccine acceptance depends on perceived risk of disease, level of trust in the vaccine, in the delivery system and the recommendations given by health authorities and barriers related to geographic accessibility and, availability of vaccination services (34). Analysis of the temporal distribution of variants causing initial infection did not reveal any obvious patterns that would suggest a bias for reinfections toward an identified variant in first infection.…”

Section: Discussionmentioning

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Milder outcomes of SARS-CoV-2 genetically confirmed reinfections compared to primary infections with the delta variant: A retrospective case-control study

Suljič

Sočan²,

Mrzel³

et al. 2022

Front. Med.

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BackgroundSARS-CoV-2 infection does not confer long immunity. However, studies suggest that prior infection is associated with lower risk of reinfection and milder outcomes of recurrent infections. The aims of this retrospective observational case-control study were to describe the clinical and molecular characteristics of genetically confirmed Delta reinfection cases and to assess the potential protective role of preceding infection on the severity of reinfection.MethodsWe used next generation sequencing (NGS) to explore if cases with two positive real time RT-PCR tests > 90 days apart were infected with a different SARS-CoV-2 variant. Cases with confirmed reinfection between August 1st and October 31st, 2021 (the Delta wave) in Slovenia were matched 1:4 by age, sex and timeframe (week of positive test) with individuals with primary infection. Sociodemographic and epidemiologic data, vaccination status, and data on hospitalization and outcome of infection were retrieved from several centralized and standardized national databases. Additional epidemiologic surveys were performed on a limited number of cases and controls.ResultsWe identified 628 cases of genetically confirmed reinfection during the study period and matched them with 2,512 control subjects with Delta primary infection. Primary infections in individuals with reinfection were mainly caused by B.1.258.17 (51.1%), followed by B.1.1.7 (15.1%) and reinfection was detected on average 271 days after primary infection (range 101–477 days). Our results show a substantially lower probability of hospitalization in cases with reinfection compared with controls (OR: 0.21, p = 0.017), but no significant difference was observed in intensive care unit admission and deaths. We observed a significantly lower proportion of vaccinated individuals among cases compared to controls (4.5% vs. 28.2%), suggesting that hybrid immunity leads to lower probability of reinfection. Detailed analysis of the temporal distribution of variants, responsible for reinfections, showed no significant differences in reinfection potential.ConclusionReinfection with the SARS-CoV-2 Delta variant resulted in fewer hospitalizations compared to the primary Delta infection, suggesting that primary infection may, to some extent, produce at least short lasting protective immunity. This study provides additional insight into the reinfection dynamics that may allow appropriate public health measures to be taken in subsequent waves of the COVID-19 pandemic.

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“…Children with high SES had a high COVID-19 vaccination rate of 50.5%, which was significant in both the univariate analysis and multivariate analyses. A recent systematic review and meta-analysis to determine the acceptance rate of the COVID-19 vaccine and the related factors showed that the COVID-19 acceptance rate was higher among individuals with high SES (31).…”

Section: Discussionmentioning

confidence: 99%

How to increase COVID-19 vaccine uptake among children? determinants associated with vaccine compliance

Hoshen

Zemer²,

Ashkenazi³

et al. 2023

Front. Pediatr.

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ObjectiveThree aims: to elucidate determinants associated with COVID-19 vaccine uptake in children and the association with parental vaccination; to compare rates of PCR-positive SARS-CoV-2 results between vaccinated and unvaccinated children; to estimate the rate of parental COVID-19 vaccination and its association with the vaccination rate of their children.MethodsWe performed a retrospective chart review of all children aged 5–11 years registered at a central district in Israel from November 21st, 2021 to April 30th, 2022, and characterized COVID-19 vaccinated vs. unvaccinated individuals. Data retrieved from the electronic medical files included: demographics [age, gender, sector, socioeconomic status (SES)]; COVID-19 vaccination (first and second doses) and influenza vaccination status; co-morbidities; and parental vaccinations for COVID-19. We divided the population into three distinct demographic groups: non-ultra-orthodox Jews (43,889 children), ultra-orthodox Jews (13,858 children), and Arabs (4,029 children).ResultsOf the 61,776 children included in the study, 20,355 (32.9%) received at least one dose of the COVID-19 vaccine. Vaccination rates were similar amongst males and females and were higher in children aged 9–11 years compared to children aged 5–6 years. Multivariate analysis identified five independent determinants that were significantly (p < 0.001) associated with low vaccination rates: Arab and ultra-orthodox sectors (odds ratios: 0.235 and 0.617, respectively); children aged 5–8 years; children of low SES; and children who had not received previous seasonal influenza vaccination. Relatively high vaccination rates were noted amongst children with the following medical co-morbidities: treatment with biological agents (42.9%); solid tumor transplantation (42.9%); type 1 diabetes mellitus (38.5%), asthma (38.2%), and attention deficit and hyperactivity disorder (ADHD) (37.6%). Regarding the uptake of two vaccine doses among children with co-morbidities, it was highest in those with type 1 diabetes mellitus, heart failure, treatment with biological agents, asthma and obesity.ConclusionThis study highlights several pediatric sub-populations with low and high vaccine uptake. It is essential to focus on determinants associated with low vaccination rates.

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Evaluation of the Acceptance Rate of Covid-19 Vaccine and its Associated Factors: A Systematic Review and Meta-analysis

Cited by 18 publications

References 128 publications

Evaluation of response to different COVID‐19 vaccines in vaccinated healthcare workers in a single center in Iran

Evaluation of response to different COVID‐19 vaccines in vaccinated healthcare workers in a single center in Iran

Milder outcomes of SARS-CoV-2 genetically confirmed reinfections compared to primary infections with the delta variant: A retrospective case-control study

How to increase COVID-19 vaccine uptake among children? determinants associated with vaccine compliance

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