Evaluation of spermatogenesis in prepubertal albino rats with date palm pollen supplement

Abstract

It is suggested that Date Palm Pollen (DPP) increases the concentration of testosterone, follicle stimulating hormone, and luteinizing hormone in rats. We therefore planned this study to examine the effect of DPP on spermatogenesis using prepubertal rats. 4-day old rats were randomly divided into four groups of 12 pups each (Control I, Experimental I, Control II, and Experimental II). Experimental groups I and II were given DPP suspension in a single oral dose of 120 mg/kg daily for 18 and 35 days, respectively. Pups were sacrificed on days 22 and 39 post-natally. Testes were removed for microscopic studies, and spermatogenesis was assessed by a method which depended upon scoring 'cross sectional' profiles of seminiferous tubules according to Johnsen's criterion. There was no statistically significant difference in Control and Experimental groups I. However Pups of the treated group II, who received DPP for 35 days, showed statistically significant increase in seminiferous tubules containing spermatozoa, resulting in a higher Johnsen Score (Control group II: 6.28 ± 0.21, Experimental group II: 8.06 ± 1.21). This implied that spermatogenesis was present at an advanced stage in the Experimental group as compared to the Control group of animals.

Effects of Phoenix dactylifera pollen grains extract supplementation on post-thaw quality of Arabian stallion semen

“…Various studies have concluded that dietary supplementation could improve spermatogenesis, increase sperm counts, motility, and increase the concentration of testosterone, FSH and LH (Salman et al, 2014;Baharara et al, 2015;El-Kashlan et al, 2015;Rasekh et al, 2015). Also, DPPG is a rich source of natural antioxidants.…”

Protective effects of date palm pollen extract on gentamicin-induced hepatotoxicity

“…DPP also contains minerals (cobalt, magnesium, copper, iron, selenium, zinc, boron and nickel), vitamins (A, C and E) and steroid compounds such as estradiol, estriol and estrone, which can be used to treat infertility (El-Kashlan et al, 2015;Hassan, 2011). Besides, it has been reported that DPP is a good source of natural antioxidants (Iftikhar et al, 2014). Many studies have shown that DPP has several effects such as reducing the expression of inflammato-ry cytokines such as IL-6, IL-8 and TNF-α as well as anti-inflammatory (Elberry et al, 2011), antioxidant (Abbas andAteya, 2011), anticoccidial, anti-apoptosis (Metwaly et al, 2014), anti-angiogenesis (Rasouli et al, 2018) and hypoglycemic (Mohamed et al, 2018) effects.…”