Evaluation of Silicone Elastomer Catheters for Long-Term Intravenous Chemotherapy

Peripherally inserted central venous lines versus central lines in surgical newborns — A comparison

“…1,4,9,10 Evidence that PICLs can be used for longer periods, if necessary , is provided by Legha and associates, who reported a median duration of catheter function of 238 days (range 2 to 521 days). 11 This is a distinct advantage of PICLs over CLs. In the present study also 88.5% of the PICL were removed electively after the completion of therapy while only 62.5% of the CLs could be maintained till the completion of therapy (Fig.…”

“…The life of IV cannula is 1.2 -2.9 days 15 which is less when compared to PICL (average 2-4 wk). 11 The IV cannula hence has to be changed frequently to maintain long-term venous access and thus rapidly exhausts access sites. 1 Pain during repeated insertions of IV cannula and immobilization of a joint can be avoided if PICL is used.…”

Development of antimicrobial‐loaded polyurethane films for drug‐eluting catheters

“…However, increasing concerns over the cytotoxicity of latex have led researchers to focus on silicone resin as a potential catheter material. Silicone resin turned out to be a promising material and appeared in several catheter studies . Nonetheless, poor mechanical performance of silicone enhanced the interest in polyurethane‐based catheters which have often proven superior performance over the silicone ones …”