Evaluation of Residual Pesticides in Commercial Agricultural Products Using LC-MS/MS in Korea

이화미,; 허수정,; 이현숙,; 박승영,; 김남선,; 신용우,; 최근화,; 김성일,; 남슬이,; 조대현,

doi:10.9721/kjfst.2013.45.4.391

Cited by 7 publications

(6 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Lee et al (2008) analysed a set of wild honeys and comb honeys produced in the Republic of Korea as well as imported products. Most honey types from domestic and foreign origin did not contain measurable amounts of GTX I, II and III (LOD: 0.15 mg/kg).…”

Section: Assessmentmentioning

confidence: 99%

“…From these surveys, it can be concluded that there is a wide variation in total GTX concentration in the samples originating from the Black Sea region, ranging from < 0.001 mg/kg to 74 mg/kg. Lee et al (2008) analysed a set of wild honeys and comb honeys produced in the Republic of Korea as well as imported products. Most honey types from domestic and foreign origin did not contain measurable amounts of GTX I, II and III (LOD: 0.15 mg/kg).…”

Section: Grayanane Occurrence In Non-european Honeysmentioning

confidence: 99%

“…Optionally an organic or inorganic acid is added (These et al., 2015; Aygun et al., 2018) and the sample may be heated to facilitate dissolution of the honey matrix (Sibel et al., 2014; Silici et al., 2016). Solid‐phase extraction (SPE) on C18 or polymeric phase cartridges has been used to clean the sample (Lee et al., 2008; Kurtoglu et al., 2014; Sibel et al., 2014; These et al., 2015; Silici et al., 2016). Determination of GTXs in honey using a dilute‐and‐shoot approach has been described (Kaplan et al., 2014).…”

Section: Introductionmentioning

confidence: 99%

“…Grayananes are often isolated from plants by methanol or chloroform extraction followed by further purification and crystallisation (Koca and Koca, 2007). GTXs can be extracted from honey using aqueous solutions, often in combination with methanol as organic modifier to improve extraction (Lee et al., 2008; Kaplan et al., 2014; Kurtoglu et al., 2014). Optionally an organic or inorganic acid is added (These et al., 2015; Aygun et al., 2018) and the sample may be heated to facilitate dissolution of the honey matrix (Sibel et al., 2014; Silici et al., 2016).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Risks for human health related to the presence of grayanotoxins in certain honey

Schrenk¹,

Bignami²,

Bodin³

et al. 2023

EFS2

View full text Add to dashboard Cite

The European Commission asked EFSA for a scientific opinion on the risks for human health of the presence of grayanotoxins (GTXs) in ‘certain honey’ from Ericaceae plants. The risk assessment included all structurally related grayananes occurring with GTXs in ‘certain’ honey. Oral exposure is associated with acute intoxication in humans. Acute symptoms affect the muscles, nervous and cardiovascular systems. These may lead to complete atrioventricular block, convulsions, mental confusion, agitation, syncope and respiratory depression. For acute effects, the CONTAM Panel derived a reference point (RP) of 15.3 μg/kg body weight for the sum of GTX I and III based on a BMDL 10 for reduced heart rate in rats. A similar relative potency was considered for GTX I. Without chronic toxicity studies, an RP for long‐term effects could not be derived. There is evidence for genotoxicity in mice exposed to GTX III or honey containing GTX I and III, showing increased levels of chromosomal damage. The mechanism of genotoxicity is unknown. Without representative occurrence data for the sum of GTX I and III and consumption data from Ericaceae honey, acute dietary exposure was estimated based on selected concentrations for GTX I and III reflecting concentrations measured in ‘certain’ honeys. Applying a margin of exposure (MOE) approach, the estimated MOEs raised health concerns for acute toxicity. The Panel calculated the highest concentrations for GTX I and III below which no acute effects would be expected following ‘certain honey’ consumption. The Panel is 75% or more certain that the calculated highest concentration of 0.05 mg for the sum of GTX I and III per kg honey is protective for all age groups regarding acute intoxications. This value does not consider other grayananes in ‘certain honey’ and does not cover the identified genotoxicity.

show abstract

Section: Assessmentmentioning

confidence: 99%

Section: Grayanane Occurrence In Non-european Honeysmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Risks for human health related to the presence of grayanotoxins in certain honey

Schrenk¹,

Bignami²,

Bodin³

et al. 2023

EFS2

View full text Add to dashboard Cite

show abstract

“…2016∼2021년 인천, 경기지역 유통 농산물에서 부적합 농산물은 시설재배 조건에서 연중 수확이 가능한 엽채류가 70% 이상으로 높았 으며, 엽채류 중 쑥갓은 매년 지속적으로 부적합이 발생하여 잔류농약에 대한 안전성 확보를 위한 방안으로 쑥갓에 등록 된 농약의 생산단계 잔류허용기준 설정을 위한 연구가 필요 하다 [11]. 생산단계부터 유통단계까지 농산물 중 잔류농약이 MRL 이하의 안전한 수준으로 관리되어도, 소비자는 가정에 서 농산물 섭취시 잔류농약에 대한 막연한 불안감이 있으며, 불안감 해소 방안으로 농산물의 세척방법에 따른 농약 잔류 량 감소에 관한 연구들이 수행되었으나, 연구 방법에 있어 구 입한 농산물에 농약을 침지 등의 방법으로 처리한 후 세척하 는 방법으로 [12][13][14] 2). 엽채류에서 azoxystrobin의 생물학적 반감기는 갯기름나물 10.7일, 근대 5-8일, 시금치 7.9-13일, 엇갈이배추 6.3-7.4일, 치커리 4.9-5 일, 상추 4.87-6.23일로 쑥갓 중 azoxystrobin의 반감기와 유사하였다(MFDS, 2019; MFDS, 2022) [19][20][21].…”

unclassified

Risk Assessment of Azoxystrobin Residues in Fresh Crown Daisy from Farm to Fork

Ban¹,

Oh²,

Chang³

2023

Korean Journal of Environmental Agriculture

View full text Add to dashboard Cite

The biological half-life and dissipation rate of azoxystrobin in crown daisy were calculated to establish the pre-harvest residue limits (PHRLs). The pesticide residues were calculated after washing with five different processes to propose an effective process in the household and conducted a risk assessment to confirm dietary safety. Azoxystrobin was sprayed according to the critical good agricultural practices (cGAP) in two different field trials, and the samples were harvested 7 times. The limit of quantitation was 0.02 mg/kg, and the mean recoveries of azoxystrobin were within the range of 70∼120% with below 20% coefficient variation at the concentration of 0.02 and 0.2 mg/kg . The biological half-lives were 7.4 and 4.7 days, and the dissipation rate constants were 0.0872 and 0.1217 in fields 1 and 2, respectively. The average removal rates were 58.13∼78.13% by the different washing processes, and there were significant differences between the washing processes (one-way ANOVA analysis and post-hoc Duncan test, p-value<0.05). The residues of azoxystrobin in crown daisy were safe levels from farm to fork after application with the critical good agricultural practice (cGAP) registered in Korea.

show abstract

Detecting and Mapping Harmful Chemicals in Fruit and Vegetables Using Nanoparticle-Enhanced Laser-Induced Breakdown Spectroscopy

Zhao

et al. 2019

Sci Rep

View full text Add to dashboard Cite

Residues of harmful chemicals in fruit and vegetables pose risks to human health. Ordinary laser-induced breakdown spectroscopy (LIBS) techniques are unsatisfactory for detecting harmful chemicals in fruit and vegetables. In this study, we applied metal nanoparticles to fruit and vegetables samples to improve the ability of LIBS to detect trace pesticide and heavy metal residues in the samples. The nanoparticle-enhanced LIBS technique gave pesticide residue detection limits for fruit and vegetables two orders of magnitude lower than achieved using standard LIBS and heavy metal detection limits markedly better than achieved using standard LIBS. We used the nanoparticle-enhanced LIBS technique to study the distributions of harmful chemicals in vegetable leaves. We found that heavy metals are distributed unevenly in edible plant leaves, the heavy metal concentrations being higher in the veins than in the mesophyll.

show abstract

Evaluation of Residual Pesticides in Commercial Agricultural Products Using LC-MS/MS in Korea

Cited by 7 publications

References 4 publications

Risks for human health related to the presence of grayanotoxins in certain honey

Risks for human health related to the presence of grayanotoxins in certain honey

Risk Assessment of Azoxystrobin Residues in Fresh Crown Daisy from Farm to Fork

Detecting and Mapping Harmful Chemicals in Fruit and Vegetables Using Nanoparticle-Enhanced Laser-Induced Breakdown Spectroscopy

Contact Info

Product

Resources

About