Risks for human health related to the presence of grayanotoxins in certain honey

Schrenk, Dieter; Bignami, Margherita; Bodin, Laurent; Chipman, J.K.; Mazo, Jesús del; Grasl‐Kraupp, Bettina; Högstrand, Christer; Hoogenboom, L.A.P.; Leblanc, Jean‐Charles; Nebbia, Carlo; Nielsen, Elsa; Ntzani, Evangelia; Petersen, Annette; Sand, Salomon; Schwerdtle, Tanja; Vleminckx, Christiane; Dusemund, Birgit; Hart, Andrew; Mulder, Patrick P.J.; Viviani, Bárbara; Anastassiadou, Maria; Cascio, Claudia; Riolo, Francesca; Wallace, Heather M.

doi:10.2903/j.efsa.2023.7866

Cited by 3 publications

(2 citation statements)

References 187 publications

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“…The CONTAM and FEEDAP Panels used the default values for body weight and feed intake of the food and non‐food‐producing animals reported in the FEEDAP Panel guidance on the safety for the target species (EFSA FEEDAP Panel, 2017) and, when necessary, the values available in published guidelines on nutrition and feeding and in other scientific publications, already described in Opinions adopted by the CONTAM Panel (EFSA CONTAM Panel, 2023, 2024). These default values are reported in Appendix A.…”

Section: Data and Methodologiesmentioning

confidence: 99%

Animal dietary exposure in the risk assessment of contaminants in feed

Bampidis,

Azimonti,

Bastos

et al. 2024

EFS2

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EFSA performs dietary exposure assessments for food‐producing and non‐food‐producing animals to deliver risk assessment for mandates on the presence of contaminants in feed. The CONTAM and FEEDAP Panels identified the need to update the animal dietary exposure assessment model used in those assessments in CONTAM Scientific Opinions since 2011 in cases where insufficient occurrence data are available on species specific compound feeds. The Panels proposed in this statement a series of model diets based on groups of feed materials with the possibility to use different feed materials in their formulation. The Panels considered that the currently proposed model diets cover the need of the CONTAM Panel to assess the dietary exposure of animals to contaminants in feed.

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Section: Data and Methodologiesmentioning

confidence: 99%

Animal dietary exposure in the risk assessment of contaminants in feed

Bampidis,

Azimonti,

Bastos

et al. 2024

EFS2

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“…Нерододендроновый мед из Agarista salicifolia связан с острыми отравлениями людей на французском острове Реюньон. Исследования в этом направлении продолжаются [23].…”

Section: миф 5 «чай и кофе под запретом во время беременности»unclassified

Nutrition During Pregnancy: Myths and Facts

Ненартович

2023

Репродуктивное Здоровье. Восточная Европа

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Беременность вызывает трепетные ощущения и порой растерянность по поводу необходимости изменения образа жизни, в том числе подхода к питанию, что выражается в диаметральном разбросе предложений и рекомендаций в открытых источниках информации. С одной стороны, обыватели полагают, что беременной нельзя ни в чем отказывать и есть ей следует за двоих. С другой стороны, из-за необоснованных страхов риска возможной аллергии резко урезается рацион нерациональными запретами на употребление орехов, цитрусовых, рыбы и морепродуктов, шоколада и других продуктов. Материнское ожирение, материнское недоедание и гестационный сахарный диабет ассоциированы с осложнениями беременности и негативными последствиями для здоровья детей. Беременные женщины с ожирением (с перееданием в результате избыточного потребления энергии) могут в то же время испытывать дефицит целого ряда нутриентов, обусловленный употреблением пищи с недостаточным содержанием микронутриентов. Дефицит микронутриентов и избыточная масса тела или ожирение могут накладываться друг на друга, что усиливает риск развития трансгенерационных неинфекционных заболеваний. Статья представляет собой попытку систематизации современных представлений об организации безопасного и полезного питания беременной. Pregnancy causes trembling sensations and sometimes confusion regarding lifestyle, including approaches to nutrition, which is expressed in the diametrical scattering of proposals and recommendations in open sources of information. On the one hand, ordinary people believe that a pregnant woman should not be denied anything, and that she should eat for two. On the other hand, due to unfounded fears of the risk of possible allergies, the diet is sharply reduced by irrational bans on the consumption of nuts, citrus fruits, fish and seafood, chocolate and coffee. Maternal obesity, maternal malnutrition, and gestational diabetes mellitus are associated with pregnancy complications and negative health outcomes in children. Obese pregnant women (overeating due to excess energy intake) may at the same time be deficient in a number of nutrients due to consumption of micronutrient deficient foods. Micronutrient deficiencies and overweight or obesity may overlap, increasing the risk of developing transgenerational noncommunicable diseases. The article is an attempt to systematize modern ideas about the organization of safe and healthy nutrition for a pregnant woman.

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Underexplored food safety hazards of beekeeping products: Key knowledge gaps and suggestions for future research

Végh,

Csóka,

Sörös

et al. 2024

Comp Rev Food Sci Food Safe

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These days, a growing consumer demand and scientific interest can be observed for nutraceuticals of natural origin, including apiculture products. Due to the growing emphasis on environmental protection, extensive research has been conducted on the pesticide and heavy metal contamination of bee products; however, less attention is devoted on other food safety aspects. In our review, scientific information on the less‐researched food safety hazards of honey, bee bread, royal jelly, propolis, and beeswax are summarized. Bee products originating from certain plants may inherently contain phytotoxins, like pyrrolizidine alkaloids, tropane alkaloids, matrine alkaloids, grayanotoxins, gelsemium alkaloids, or tutin. Several case studies evidence that bee products can induce allergic responses to sensitive individuals, varying from mild to severe symptoms, including the potentially lethal anaphylaxis. Exposure to high temperature or long storage may lead to the formation of the potentially toxic 5‐hydroxymethylfurfural. Persistent organic pollutants, radionuclides, and microplastics can potentially be transferred to bee products from contaminated environmental sources. And lastly, inappropriate beekeeping practices can lead to the contamination of beekeeping products with harmful microorganisms and mycotoxins. Our review demonstrates the necessity of applying good beekeeping practices in order to protect honeybees and consumers of their products. An important aim of our work is to identify key knowledge gaps regarding the food safety of apiculture products.

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Risks for human health related to the presence of grayanotoxins in certain honey

Cited by 3 publications

References 187 publications

Animal dietary exposure in the risk assessment of contaminants in feed

Animal dietary exposure in the risk assessment of contaminants in feed

Nutrition During Pregnancy: Myths and Facts

Underexplored food safety hazards of beekeeping products: Key knowledge gaps and suggestions for future research

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