Evaluation of reduction kinetics of 2,2-diphenyl-1-picrylhydrazyl radical by flavonoid glycoside Rutin in mixed solvent based micellar media

Chat, Oyais Ahmad; Najar, Muzaffar Hussain; Dar, Aijaz Ahmad

doi:10.1016/j.colsurfa.2013.06.035

Cited by 18 publications

(13 citation statements)

References 43 publications

(55 reference statements)

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“…For better understanding the efficient inhibition of DPPH radical, a total time interval of 240 min was chosen to measure the absorbance at the steady state. Such an approach was reported by Kedare et al [31] and Chat et al [29]. These results, presented in Table II, emphasized that Enoxil showed a fast decrease time evolution followed by a slow antiradical kinetics reaching endpoint at 240 min.…”

Section: Dpph Assaysupporting

confidence: 69%

Enhanced Biomedical Properties of Chitosan-Enoxil Films

Duca¹

2019

FARMACIA

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Polyphenolic compounds show antioxidant activities by inhibiting the formation of free radicals. Using eco-friendly reactions, which involve oxidation and depolymerization of grape seed tannins, new products for biomedical applications are obtained. Especially, it is of high interest the valorisation of by-products such as grape seeds, which are in considerable quantities in the Republic of Moldova. However, these products are highly labile to environment risk factors. Therefore, the use of polymeric materials, especially by-products such as chitin and chitosan, is a perspective way to design dressing materials such as biomedical films. This paper studies the change of antioxidant activity and bacteria growth inhibition of the synthetized chitosan-Enoxil film. It was demonstrated that the addition of Enoxil to chitosan film in the concentration of 5% improves antibacterial properties against Bacillus subtilis, Pseudomonas fluorescens and Candida utilis. Moreover, these biofilms have proved an efficient inhibition of the cation ABTS radical (0.42 mg-echiv/mL Tox) and DPPH radical (23.66 % remaining DPPHc). Incorporation of polyphenolic acids to chitosan films could improve the overall lifetime of the food products storage. RezumatCompușii polifenolici manifestă proprietăți antioxidante prin inhibarea formării radicalilor liberi. Folosind reacții eco-friendly, care implică oxidarea și depolimerizarea taninurilor din semințe de struguri, pot fi obținute produse noi pentru aplicații biomedicale. În special, prezintă interes valorificarea produselor secundare, precum semințele de struguri, care sunt în cantități considerabile în Republica Moldova. Totodată, aceste produse sunt extrem de labile la factorii de risc a mediului ambiant. Prin urmare, utilizarea materialelor polimerice cum ar fi produșii secundari chitina și chitosan, reprezintă o perspectivă de a fabrica biomateriale cum sunt filmele biomedicale. În cadrul acestei lucrări a fost studiată modificarea activității antioxidante și antibacteriene a bio-materialelor sintetizate chitosan-Enoxil. S-a stabilit că la adăugarea de Enoxil în filme de chitosan în concentrație de 5% se îmbunătățesc proprietățile antibacteriene împotriva Bacillus subtilis, Pseudomonas fluorescens și Candida utilis. De asemenea, aceste biofilme sunt eficiente în inhibarea cationului radical ABTS (0,42 mg-echiv/mL Tox) și radicalului DPPH (23,66%, conc. DPPH remanent). Încorporarea acizilor polifenolici în filme de chitosan ar putea îmbunătăți durata de viață a produselor alimentare la stocare.

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Section: Dpph Assaysupporting

confidence: 69%

Enhanced Biomedical Properties of Chitosan-Enoxil Films

Duca¹

2019

FARMACIA

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“…This acceleration may reflect not only favourable confinement and orientation of reagents in micelles (Noipa et al, 2011;Chat et al, 2013) but also a shift of the mechanism from H-transfer to electron-transfer because of the increased polarity (Di Meo et al, 2013).…”

Section: Scavenging Of Dpph Radical In Aqueous Micellar Solutionmentioning

confidence: 94%

Antioxidant activity of olive phenols and other dietary phenols in model gastric conditions: Scavenging of the free radical DPPH and inhibition of the haem-induced peroxidation of linoleic acid

et al. 2016

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The antioxidant activity of dietary phenols in humans (direct reduction of radicals and other highly oxidizing species) could be largely restricted to fighting postprandial oxidative stress in the gastric compartment. Hence, the development of chemical tests simply modelling this situation is pertinent. In this work, the antioxidant properties of the olive phenols hydroxytyrosol and oleuropein are investigated in pH 5-6 micellar solutions through the reduction of the DPPH radical and the inhibition of the metmyoglobin-induced peroxidation of linoleic acid. In the first test, hydroxytyrosol and oleuropein proved as efficient as common polyphenols and their reactivity was only moderately affected by β-cyclodextrin and bovine serum albumin, taken as models of food macromolecules. In the second test, hydroxytyrosol and oleuropein by themselves came up as relatively weak inhibitors, despite their efficiency at reducing hypervalent haem iron. However, hydroxytyrosol was able to act in synergy with the typical chain-breaking antioxidant α-tocopherol.

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“…Nature is abundant with antioxidants. A number of natural antioxidants are available; examples include vitamin E from food 15,16 as well as b-caronoids, 17,18 lycopene, 19 capsaicin, 20 resveratrol, 21 curcumin, 22 piceatannol, 23 catechin, 24 rutin, 25 myricetin, 26 puerarin, 27 artemisinin, 28 gallic acid, 29 ferulic acid, 30 quercetin, 31 apigenin, 32 chrysin 32 from plant extracts.…”

Section: Introductionmentioning

confidence: 99%