Evaluation of Physico Chemical Properties and Diuretic Activity of Biotite Calx (Abhraka Bhasma) Processed With Tribulus Terrestris L.: An Experimental Study

Abstract

Ayurvedic formulations have been used for centuries with claimed safety and efficacy. The aim of the present study was to evaluate the diuretic effect of Gokshura Kwatha Marita Abhraka Bhasma (biotite calx incinerated with the decoction of Tribulus terrestris L.) in experimental animals. The animals were randomly selected and divided into three groups, each comprising 8 animals. The diuretic activity of Abhraka Bhasma (biotite calx) was evaluated by determining volume, pH and electrolyte concentration of urine in male albino rats at a single dose of 4.5 mg for 200g body weight. Furosemide was used as reference standard and normal saline was used as normal control. Abhraka Bhasma treated rats have shown significant increase in the volume of urine and urinary electrolyte concentrations of Na + , K + and Cl -ions in comparison to normal control. Thus, these results indicate that Abhraka Bhasma processed with the decoction of Tribulus terrestris L. could have potent diuretic activity.

Understanding the effects of Abhraka Bhasma on genotoxicity and its DNA repair potential in mouse model

“…It is also considered as rasayana and comprehensively used as a rejuvenator, aphrodisiac, anti-ageing and health promoter. There are evidence on hepatoprotective [ [4] , [5] , [6] ], anti-diuretic [ 7 ], anti-stress, anti-inflammatory and immunomodulatory [ 8 ], adaptogenic [ 9 ], memory-enhancing [ 10 ], anti-cancer [ 11 ], and anti-diabetic [ 3 ] role of Abhraka Bhasma .…”

Biotite-Calx Based Traditional Indian Medicine Sahastraputi-Abhrak-Bhasma Prophylactically Mitigates Allergic Airway Inflammation in a Mouse Model of Asthma by Amending Cytokine Responses

“…14 It protects from various types of cancers, 13 CCl 4 induced hepatitis 15 and improves kidney and liver function 16 and exerts diuretic activity. 17 Shataputi abhrak bhasma and SPAB are considered to be finest form of biotite-calx (mica based) bhasma 14 and contains immunomodulatory properties. 18 SPAB has been shown to protect from heat-induced oligozoospermia and azoospermia, possibly by modulating p53 and Fas mediated apoptotic pathways and ameliorates germinal epithelial proliferation.…”