Evaluation of Outflow Structures<i>In Vivo</i>after the Phacocanaloplasty

Paulaviciute-Baikstiene, Daiva; Vaičiulienė, Renata; Jašinskas, Vytautas; Janulevičienė, Ingrida

doi:10.1155/2016/4519846

Cited by 7 publications

(2 citation statements)

References 33 publications

(43 reference statements)

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“…Wang et al showed that there was a significantly reduced cross‐sectional area of Schlemm's canal in patients with primary open angle glaucoma . Studies from 2016 also demonstrated that the size of Schlemm's canal increased in patients post‐canaloplasty, an increase that correlated with a decrease in intraocular pressure …”

Section: Resultsmentioning

confidence: 94%

Anterior segment optical coherence tomography and its clinical applications

Wang

Cornish

Grigg

et al. 2019

Clinical and Experimental Optometry

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Anterior segment optical coherence tomography (AS-OCT) has become one of the cornerstones of non-contact imaging modalities for assessing such structures as the cornea, anterior chamber angle, aqueous outflow pathway, sclera, and ocular surface structures. As such, it has a broad range of clinical applications, which have been independently reported in the literature. This paper aims to present a review of extant literature on the utility of AS-OCT and its efficacy in clinical applications, and to evaluate the quality of available evidence. The following databases were searched from inception to 24 June 2018: Medline via Ovid, Cochrane Central Register of Controlled Trials, PubMed, World Health Organization International Clinical Trials Registry Platform, EMBASE, and CINAHL. Bibliographies of identified papers were hand searched. Inclusion criteria: articles describing or assessing the use of OCT for visualising the AS. The authors excluded studies without an identified primary outcome variable. One author independently selected studies, extracted data, and assessed for risk of bias using PRISMA guidelines. This review included 82 studies, of which there were 11 cohort studies, 37 case series, 10 case studies, 21 comparative observational studies, and three non-systematic review articles. Primary outcome variables included anterior chamber angle, angle opening distance, angle recess area, trabecular iris angle, trabeculairis space area, corneal thickness, tear meniscus height, tear meniscus area, tear meniscus volume, and the morphology of AS structures, including the ocular surface, blebs, flaps, and graft sites. This review attempts to encompass the breadth and depth of evidence for AS-OCT in the arena of diagnostics, therapeutics, and prognostics. At the same time, it brings to light the dearth of high-level evidence on this topic, suggesting the important role of randomised controlled trials and meta-analyses for the future validation of this technology.

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Section: Resultsmentioning

confidence: 94%

Anterior segment optical coherence tomography and its clinical applications

Wang

Cornish

Grigg

et al. 2019

Clinical and Experimental Optometry

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“…2) [20,21]. Dadurch kann der Einfluss medi-kamentöser Therapien [22,23] und operativer Verfahren, wie Kataraktextraktion oder Kanaloplastik, auf die Schlemm-Kanal-Anatomie untersucht werden [24,25]. So wurde gezeigt, dass die Applikation von Prostaglandinaugentropfen zu einer Dilatation des Schlemm-Kanals führt, was auf eine frühe trabekuläre Wirkkomponente der Tropfen hinweist [22].…”

Section: Schlemm-kanalunclassified

Bildgebung der intraskleralen Kammerwasserabflusswege – neue Einblicke für die Trabekelwerkschirurgie

Oterendorp

2017

Klin Monatsbl Augenheilkd

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Numerous new techniques in glaucoma surgery target the trabecular meshwork, which is considered to be the main site of aqueous outflow resistance. These approaches rely on a functioning aqueous drainage system distal to the site of surgery. Thus, the intrascleral aqueous outflow tract comprises Schlemm's canal, collector channels and aqueous veins and has become an object of increasing research interest. The intrascleral outflow tract contributes approximately 25-50 % to the total aqueous outflow resistance, but the outflow capacity differs greatly over the segments of the eye. Morphological and functional assessment of the intrascleral outflow tract is challenging, due to its deep scleral location and the complex nature of its small diameter vessel network. In this review, we present novel insights into its morphology and function, based on advances in a variety of imaging modalities, including optical coherence tomography, fluorescence imaging and electron microscopy. Together with clinical data, they support the paradigm of significant sectorial differences in aqueous outflow, which has a direct impact on glaucoma surgery targeting sectors of the trabecular meshwork, such as trabeculectomy ab interno or trabecular meshwork bypass stents. Possible future applications of intrascleral outflow tract imaging are discussed.

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Clinical Applications in Medical Practice

Paulaviciute-Baikstiene

Vaičiulienė

2019

Biophysical Properties in Glaucoma

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Evaluation of Outflow StructuresIn Vivoafter the Phacocanaloplasty

Cited by 7 publications

References 33 publications

Anterior segment optical coherence tomography and its clinical applications

Anterior segment optical coherence tomography and its clinical applications

Bildgebung der intraskleralen Kammerwasserabflusswege – neue Einblicke für die Trabekelwerkschirurgie

Clinical Applications in Medical Practice

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