Anterior segment optical coherence tomography and its clinical applications

Wang, Sarah B.; Cornish, Elisa E; Grigg, John; McCluskey, Peter

doi:10.1111/cxo.12869

Cited by 47 publications

(23 citation statements)

References 92 publications

(137 reference statements)

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“…A small interference packet is measured for each boundary layer along the axis. From the positions of the scanner mirror, the interference effects are measured with the optical path length [20,21]. In the Fourier domain (FD), the interferometer is not mechanically modified.…”

Section: Optical Coherence Tomography Imagingmentioning

confidence: 99%

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Comparison of Femtosecond Laser-Assisted and Ultrasound-Assisted Cataract Surgery with Focus on Endothelial Analysis

Schroeter

Kropp

Cvejić

et al. 2021

Sensors

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Femtosecond laser-assisted cataract surgery has the potential to make critical steps of cataract surgery easier and safer, and reduce endothelial cell loss, thus, improving postoperative outcomes. This study compared FLACS with the conventional method in terms of endothelial cells behavior, clinical outcomes, and capsulotomy precision. Methods: In a single-center, randomized controlled study, 130 patients with cataracta senilis received FLACS or conventional cataract surgery. Results: A significant endothelial cell loss was observed postoperatively, compared to the preoperative values in both groups. The endothelial cell counts was significantly better in the FLACS group in cataract grade 2 (p = 0.048) patients, compared to conventionally at 4 weeks. The effective phaco time was notably shorter in grade 2 of the FLACS group (p = 0.007) compared to the conventional. However, no statistically significant differences were found for the whole sample, including all cataract grades, due to the overall cataract density in the FLACS group being significantly higher (2.60 ± 0.58, p < 0.001) as compared to conventional methods (2.23 ± 0.42). Conclusions: Low energy FLACS provides a better result compared to endothelial cell loss, size, and shape variations, as well as in effective phaco time within certain cataract grade subgroups. A complete comparison between two groups was not possible because of the higher cataract grade in the FLACS. FLACS displayed a positive effect on endothelial cell preservation and was proven to be much more precise.

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Section: Optical Coherence Tomography Imagingmentioning

confidence: 99%

“…The set of A-scans is assembled to obtain an OCT image; this set of scans is called a B-scan. Accordingly, all depth information is acquired without the need for moving parts [21]. The acquired wavenumber-dependent data are converted into axial scan information by an inverse Fourier transform.…”

Section: Optical Coherence Tomography Imagingmentioning

confidence: 99%

Comparison of Femtosecond Laser-Assisted and Ultrasound-Assisted Cataract Surgery with Focus on Endothelial Analysis

Schroeter

Kropp

Cvejić

et al. 2021

Sensors

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“…Данный метод позволяет установить локализацию патологического процесса, оценить степень выраженности и скорость его прогрессирования. Кроме того, визуализация роговицы с помощью ОКТ может быть использована во время кераторефракционного хирургического вмешательства и в послеоперационном периоде [18][19][20].…”

Section: окт в диагностике заболеваний роговицыunclassified

Optical Coherence Tomography for Diagnosis and Treatment of Corneal Diseases

Fisenko¹,

Osipyan²

2021

Oftalʹmologiâ

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Optical coherence tomography (OCT) is a modern non-contact real-time imaging of anterior and posterior eye’s segments. Based on the principle of low-coherence interferometry, it provides the analysis of tissue structures. In this review, we discuss technical aspects of two different OCT platforms: Time-Domain OCT (TD-OCT), and Spectral-Domain (SD-OCT) with the use of Fourier transformation — Fourier-Domain (FD-OCT). Over the last several years, the development of OCT has increased the resolution of images by different ways of optical filtering. The usage of tunable swept laser instead of superluminescent diode in modern Swept-Source OCT (SS-OCT) provides the sufficient quality of image. Anterior segment OCT can detect the pathological changes in different ocular structures and may be a key tool for monitoring of their progression. In pterygium OCT shows the true extent of fibrovascular granulation tissue in stromal layers, whereas in keratitis it provides imaging of corneal infiltration. Frequently, OCT-pachymetry can be advantageous in the detection of subclinical keratectasias. In patients with bullous keratopathy OCT can help to distinguish corneal edema and fibrosis. The new era of OCT is characterized by application of this method in keratorefractive surgery. Microscope-mounted (portable) and microscopeintegrated OCT systems have been developed. During LASIK surgery intraoperative OCT (iOCT) helps to assess flap interface, measure flap and residual bed thickness. It is a useful tool to reveal the structural changes during corneal collagen crosslinking. At the beginning of keratoplasty, iOCT helps to determine the corneal thickness, extent and depth of opacity, Descemet membrane perforation. iOCT guides decision-making regarding keratoplasty modification, depth and diameter of trephination. Furthermore, a real-time visualization of ocular structures during keratoplasty decreases the frequency of intra- and postsurgical complications.

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“…Optical coherence tomography (OCT) was developed in the 1990s and has in many ways changed ophthalmology. Anterior segment OCT has become one of the cornerstones for assessing the cornea, the anterior chamber angle, the aqueous outflow pathway, the sclera, and other ocular surface structures . Nevertheless, to the best of our knowledge, OCT has not been applied to the study of dellen.…”

mentioning

confidence: 99%