Evaluation of omega-3 fatty acids content and antioxidant activity in wheat (Triticum aestivum L.) leaves

Aguiar, Ana Carolina de; Boroski, Marcela; Bonafé, Elton Guntendorfer; Almeida, Vanessa Vivian de; Souza, Nilson Evelázio de; Visentainer, Jesuí Vergílio

doi:10.1590/s1413-70542011000400012

Cited by 4 publications

(2 citation statements)

References 33 publications

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“…This compound possessed good correlation with DPPH scavenging activity, suggesting it is as a good antioxidant. Previous study found that wheat leaves with an abundance of α-linolenic acid exhibit considerable antioxidant activity [42]. Fructose (1) and glucaric acid (30) were weakly linked with α-glucosidase inhibitory activity.…”

Section: Relationship Between Antioxidant and α-Glucosidase Inhibitormentioning

confidence: 94%

Potentially Bioactive Metabolites from Pineapple Waste Extracts and Their Antioxidant and α-Glucosidase Inhibitory Activities by 1H NMR

Azizan

Lee

Abdul‐Hamid

et al. 2020

Foods

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Pineapple (Ananas comosus) waste is a promising source of metabolites for therapeutics, functional foods, and cosmeceutical applications. This study strives to characterize the complete metabolite profiles of a variety of MD2 pineapple waste extracts. Metabolomics strategies were utilized to identify bioactive metabolites of this variety prepared with different solvent ratios. Each pineapple waste extract was first screened for total phenolic content, 2,2-diphenyl-1-picrylhydrazyl free radical scavenging, nitric oxide scavenging, and α-glucosidase inhibitory activities. The highest TPC was found in all samples of the peel, crown, and core extracted using a 50% ethanol ratio, even though the results were fairly significant than those obtained for other ethanol ratios. Additionally, crown extracted with a 100% ethanol ratio demonstrated the highest potency in DPPH and NO scavenging activity, with IC 50 values of 296.31 and 338.52 µg/mL, respectively. Peel extracted with 100% ethanol exhibited the highest α-glucosidase inhibitory activity with an IC 50 value of 92.95 µg/mL. Then, the extracts were analyzed and the data from 1 H NMR were processed using multivariate data analysis. A partial least squares and correlogram plot suggested that 3-methylglutaric acid, threonine, valine, and α-linolenic acid were the main contributors to the antioxidant activities, whereas epicatechin was responsible for the α-glucosidase inhibitory activity. Relative quantification further supported that 100% crown extract was among the extracts that possessed the most abundant potential metabolites. The present study demonstrated that the crown and peel parts of MD2 pineapple extracted with 100% ethanol are potentially natural sources of antioxidants and α-glucosidase inhibitors, respectively.

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Section: Relationship Between Antioxidant and α-Glucosidase Inhibitormentioning

confidence: 94%

Potentially Bioactive Metabolites from Pineapple Waste Extracts and Their Antioxidant and α-Glucosidase Inhibitory Activities by 1H NMR

Azizan

Lee

Abdul‐Hamid

et al. 2020

Foods

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show abstract

“…Several previous studies reported and confirmed that there is a strong relationship between antioxidant activity and minor bioactive phytochemical components such as tocopherols, carotenoids, and omegathree fatty acid. [39,40,41] According to our results, the antioxidant activity of P. atlantica Desf. crude oils from different organs might be attributed to the presence of tocopherols, carotenoids, and unsaturated fatty acids in particular omega-three fatty acids.…”

Section: Correlations Between Tocopherols Carotenoids (C18 : 3) Omementioning

confidence: 54%

Total Tocopherols, Carotenoids, and Fatty Acids Content Variation of Pistacia atlantica from Different Organs’ Crude Oils and Their Antioxidant Activity during Development Stages

Chelghoum

Guenane

Harrat

et al. 2020

Chemistry & Biodiversity

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The current study investigated the effect of developmental stages on the chemical composition and the antioxidant activity of fifteen crude oil samples obtained from Pistacia atlantica Desf. leaves, galls, and fruits. Twelve fatty acids were detected by GC/FID, linolenic acid (C18 : 3) was the major fatty acid detected in leaves crude oils that registered [41.73 % (P<0.05)] on the last stage. The best content of tocopherols and carotenoids was recorded at the last stage for leaves and galls oils, respectively, with values of [1.530±0.01, 0.52±0.01 (P<0.05) mg α‐tocopherol equivalent/g DW] and [86.60±0.95, 69.15±0.13 (P<0.05) μg β‐carotene equivalent/g DW]. For fruits oils, the content varied depending on the levels of fruits maturation. The results from DPPH, FRAP, and ABTS assays revealed that the antioxidant activity increased with the increasing content of tocopherols and carotenoids in leaves and galls oils during development stages, and varied for fruits oils depending on the ripening stages. Moreover, according to PCA analysis, the best phytoconstituent content and antioxidant activity were attributed to P. atlantica Desf. fruit's crude oils. Also, a strong relationship was found between the antioxidant activity and bioactive phytochemical components, such as tocopherols, carotenoids, and omega‐three fatty acid, which confirmed that P. atlantica Desf. crude oils present a valuable source of natural antioxidant that could be used for pharmaceutical and food industries purposes.

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Triticum aestivum ethanolic extract improves non‐alcoholic fatty liver disease in mice fed a choline‐deficient or high‐fat diet

Cho

Tak

et al. 2019

J Sci Food Agric

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BACKGROUND: Although non-alcoholic fatty liver disease (NAFLD) has become more prevalent with the rapid increase of obesity worldwide, no specific treatment has been developed. Several studies have shown that wheatgrass extract Triticum aestivum (TA) improves lipid metabolism. In the present study, we evaluated the efficacy of GM-T (an ethanolic TA extract) in a murine NAFLD model. Mice were separated into 12 groups (n = 10): two groups of normal diet, choline-deficient diet (CDD) or high-fat diet (HFD) with vehicle, CCD or HFD with silymarin (400 mg kg −1 day −1 ), and CCD or HFD with GM-T (100, 200 or 400 mg kg −1 day −1 ). The study was performed for 8 weeks for the CDD groups and 12 weeks for the HFD groups. RESULTS:In the CDD-fed mice, GM-T improved serum liver enzyme activities and liver inflammation score compared to vehicle. In the HFD-fed mice, GM-T improved blood lipid profiles, liver inflammation score, steatosis score and obesity compared to vehicle. CONCLUSION:The present study demonstrated that GM-T effectively improved NAFLD in mice via a mechanism that improved insulin resistance and lipid metabolism, suggesting the possibility of a functional dietary supplement to improve liver health, overall metabolic syndrome and obesity. RESULTS Effects of GM-T on liver enzyme alteration in CDD-fed miceSerum liver enzyme activities were analyzed in CDD-fed mice. Serum AST, ALT, ALP and LDH levels were significantly higher in the CDD with vehicle group (the negative control) than in mice fed the normal diet. In the GM-T groups, AST levels were decreased by 5.5%, 17% and 26.9% in the 100-mg kg −1 day −1 group, the 200-mg kg −1 day −1 group and the 400-mg kg −1 day −1 group, respectively, compared to the CDD with vehicle group; these effects were dose-dependent, although this finding did not reach statistical significance. ALT levels were significantly decreased by 27.5%, 51.5% and 36.1% in the 100-mg kg −1 day −1 group, the 200-mg kg −1 day −1 group and the 400-mg kg −1 day −1 group, respectively, compared to the CDD with vehicle group. LDH levels also were significantly decreased by 36%, 40.5% and 46.7% in the 100-mg kg −1 day −1 group, the 200-mg kg −1 day −1 group and the 400-mg kg −1 day −1 group, respectively, compared to the CDD with vehicle group. However, the ALP levels did not differ significantly between the GM-T and the CDD with vehicle groups. The CDD with silymarin group (the positive control) did not show any improvement in serum liver enzyme activities (Table 1). Effects of GM-T on liver tissue in CDD-fed miceThe liver tissue samples of the CDD groups showed severe steatosis symptoms, such as macrovesicular and microvesicular fatty J Sci Food Agric

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Evaluation of omega-3 fatty acids content and antioxidant activity in wheat (Triticum aestivum L.) leaves

Cited by 4 publications

References 33 publications

Potentially Bioactive Metabolites from Pineapple Waste Extracts and Their Antioxidant and α-Glucosidase Inhibitory Activities by 1H NMR

Potentially Bioactive Metabolites from Pineapple Waste Extracts and Their Antioxidant and α-Glucosidase Inhibitory Activities by 1H NMR

Total Tocopherols, Carotenoids, and Fatty Acids Content Variation of Pistacia atlantica from Different Organs’ Crude Oils and Their Antioxidant Activity during Development Stages

Triticum aestivum ethanolic extract improves non‐alcoholic fatty liver disease in mice fed a choline‐deficient or high‐fat diet

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