Evaluation of New Anti-Neoplastic Active Ingredient in Vitro

El-Fiky, Bahgat A.; Halfawy, Khalil; El-Naggar, Mohamed; Gobba, Naglaa A.

doi:10.21608/bfsa.2008.64220

Cited by 1 publication

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It makes sense to investigate the chemical components of plants in order to screen them for the creation of innovative medicines and to determine the scientific basis for their traditional usage. Yemenis have long used plants to treat a variety of medical, physiological, mental and social illnesses, however, few scientific studies have been done on these plants [13,14,15] . The plant Actiniopteris semiflabellata Pic-Ser, (Actinopteridaceae) grows in many parts of Yemen such as Tihama foothills, Hagda, Ibb, al Baydha, Hajjah, and Socotra [16] .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of hydromethanolic extract and aglycone fraction of Actiniopteris semiflabellata for antioxidant activity

Algfri¹,

Naser²,

Rageh³

2023

J. Med. Plants Stud.

View full text Add to dashboard Cite

Actiniopteris semiflabellata Pic-Ser grows in Yemen and is used by the local population for wounds and burns. The goal of the current study was to assess the Actiniopteris semiflabellata's chemical composition and antioxidant activity. Phenols, flavonoids, triterpenes and sterols were identified in the hydromethanolic extract and in the aglycone fraction, while carbohydrates were only found in the hydromethanolic extract. In the hydromethanolic extract and the aglycone fraction, the total phenolic content was evaluated as 17.73 mg/g and 7.22 mg/g respectively, while the total flavonoid content was 11.21 mg/g and 4.13 respectively. Studied extract and fraction exhibited antioxidant activity by TLC bioautography and DPPH radical scavenging activity assay. The IC50 values for the hydromethanolic extract and the aglycone fraction were 79.64 and 148.60 µg/ml respectively. These results confirm the traditional use and are useful for further study of this plant, in addition, it may be a good source of natural antioxidants.

show abstract

Section: Introductionmentioning

confidence: 99%