Evaluation of Lysine Supplementation of Infant Formulas Fed to Rats

Section D. Nutritive value of milk and milk products

“…Associated with these increases have been slight changes in the general pattern of milk utilization. The year 1957, with an increase of 4 % over the 1956 figure, set a post-war record for butter production (23) and there was a further increase of 3 % in 1958 (24). Corresponding increases in cheese production were 4 % in 1957 and 1 % in 1958.…”

“…They emphasize the important point that the addition of methionine increases the sensitivity of the rat assay to lysine deterioration, for when this deterioration is small the difference between spray-and roller-dried skim-milk cannot be detected unless methionine is added to the diet. Failure to make this addition and to reduce the lactose contents of the diets may have been responsible for the lack of response to a lysine supplement shown by rats receiving an infant formula or diets based on evaporated milk in another study (24).…”