Evaluation of lipolysis and toxicological parameters of low-level laser therapy at different wavelengths and doses in the abdominal subcutaneous tissue

Martins, Marcia Gerhardt; Martins, Maria Isabel Morgan; Souza, Alessandra Hübner de; Antunes, Flavia Tasmin Techera; Pail, Priscilla Batista; Wiilland, Elenir de Fátima; Picada, Jaqueline Nascimento; Brum, Lucimar Filot da Silva

doi:10.1007/s10103-021-03378-y

Cited by 6 publications

(8 citation statements)

References 32 publications

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“…In the Badin et al 25 study they reported a higher energy 1064 nm Nd:YAG laser system (maximum 6 W) utility in the upper thigh upper abdomen, and periumbilical region. In the study of Martins et al they reported that noninvasive low‐level laser therapy is painless, safe, and effective in decreasing abdominal subcutaneous tissue 6 . In other study the efficacy of noninvasive 1060 nm diode laser was evaluated for abdomen fat and they informed 1060 nm based laser treatment is effective and safe procedure for reduction of the fat contour in the abdomen 16 .…”

Section: Discussionmentioning

confidence: 99%

“…In the study of Martins et al they reported that noninvasive low-level laser therapy is painless, safe, and effective in decreasing abdominal subcutaneous tissue. 6 In other study the efficacy of noninvasive 1060 nm diode laser was evaluated for abdomen fat and they informed 1060 nm based laser treatment is effective and safe procedure for reduction of the fat contour in the abdomen. 16 Recently Endolift laser was used to treat several skin disorders.…”

Section: Subject Satisfaction and Physician Assessmentsmentioning

confidence: 99%

“…In current years, noninvasive body contouring techniques have developed as an increasingly popular area of cosmetic in the aesthetic cosmetic industry 2 . Laser therapy is a novel noninvasive technique that can lyses excess fat without the adverse side effects related to surgical procedures like liposuction 3–7 . This technology can also be used to tighten the skin 8 .…”

Section: Introductionmentioning

confidence: 99%

“…2 Laser therapy is a novel noninvasive technique that can lyses excess fat without the adverse side effects related to surgical procedures like liposuction. [3][4][5][6][7] This technology can also be used to tighten the skin. 8 The use of lasers in the unwanted fat reduction was reported in the early 1990s.…”

mentioning

confidence: 99%

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Efficacy of Endolift laser for arm and under abdomen fat reduction

Nilforoushzadeh

Heidari‐Kharaji

Fakhim³

et al. 2023

J of Cosmetic Dermatology

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Section: Discussionmentioning

confidence: 99%

Section: Subject Satisfaction and Physician Assessmentsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Efficacy of Endolift laser for arm and under abdomen fat reduction

Nilforoushzadeh

Heidari‐Kharaji

Fakhim³

et al. 2023

J of Cosmetic Dermatology

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“…In recent years, noninvasive fat reduction or body contouring modalities such as cryolipolysis, 1 radiofrequency (RF), 2 low‐level laser therapy (LLLT), 3 and high‐intensity focused ultrasound (HIFU) 4 have become widespread procedures for reducing the volume of adipose tissue or cellulite. Each procedure has distinct mechanisms for stimulating apoptosis or adipose tissue necrosis and its advantages and disadvantages.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical lipolysis of subcutaneous adipose tissue in a porcine animal model

et al. 2022

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Objectives There is a considerable demand for noninvasive low‐cost fat reduction methods with fewer side effects and shorter recovery times. This study aims to develop a fat‐reduction method through electrochemical lipolysis of subcutaneous adipocytes using needle‐based electrodes, body tissue fluids, and electrical current application. Methods Electrochemical lipolysis was performed by inserting a 4‐pin needle electrode connected to a DC power supply into the pig's abdomen. Applied electrical current (0.5 and 1 mA) and treatment time (5 or 10 minutes) were varied systematically. Ultrasound imaging was performed before and after treatment to determine changes in fat thickness. Tissue samples were collected at 0, 2, and 4 weeks posttreatment for histological evaluation to determine the mechanism of action and the procedure's efficacy. Results Electrochemical subcutaneous adipose tissue lipolysis in a porcine model was achieved through hydrolysis of physiologic fluid within the vicinity of the inserted electrode where an electric current is applied, leading to localized disruption of fat cell membranes and necrosis. Electric current configuration 1.0 mA showed more pronounced lipolysis effects applied for 10 minutes, significantly decreasing adipocyte content per treatment area. The electrochemical treatment method also stimulates collagen synthesis, which helps reduce fat. Conclusions Electrochemical lipolysis is a potential new noninvasive localized technique to reduce fat. The treatment method induces fat cell necrosis via in situ reduction‐oxidation reaction by the electrochemical activation of physiologic fluid in the surrounding tissue. Electrochemical lipolysis is a simple, low‐cost, fat‐reducing treatment method without harmful side effects.

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