Evaluation of Ketofol (Ketamine Propofol combination) as total intravenous anaesthetic for burn dressing in adult patient

Samad, M. A.; Islam, Md. Saiful; Ahmed, Mai; Maruf, AA

doi:10.3329/jafmc.v8i1.13534

Cited by 4 publications

(7 citation statements)

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“…Similar results were obtained from other studies. 5,9,10,15 CONCLUSION Following Conclusions are drawn from the Present Study- Both ketamine and fentanyl in propofol infusion for short surgical procedures are equally safe and efficacious.  Infusion of propofol-ketamine and propofol-fentanyl both provides stable haemodynamics and good recovery profile.…”

Section: Discussionmentioning

confidence: 70%

“…Similar results were obtained from other studies. 1,5,8,9,10,12,13 Vallejo M. C. et al 5 also observed no statistical significance in their study. Similar results were obtained from other studies.…”

Section: Discussionmentioning

confidence: 78%

“…Similar results were obtained from other studies. 7,10,14 There was no change in mean respiratory rate in both groups immediately after the induction. After starting the infusion no significant (P ≤0.05) changes have been observed in mean RR at 5, 10, 15, 20, 25 min.…”

Section: Discussionmentioning

confidence: 82%

“…5,8,9,10,11 There was a decrease in mean SBP (119.08 ± 4.10) and (114.62 ± 6.47) in PK and PF group respectively immediately after induction. Later (mean ± SD) SBP remained stable among both groups at 5, 10, 15, 20, 25 min.…”

Section: Discussionmentioning

confidence: 87%

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A Comparative Evaluation of Ketamine-Propofol Versus Fentanyl-Propofol in Total Intravenous Anaesthesia- A Double Blind Randomised Clinical Trial

Pandey¹,

Gupta²,

Choudhary³

et al. 2017

jemds

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BACKGROUNDPropofol has emerged as a gold-standard for total intravenous anaesthesia (TIVA) for short surgical interventions but lack of analgesia remains its main shortcoming, therefore it is always combined with an analgesic. Ketamine and fentanyl are the popular analgesic in this context. This study was carried out to compare these drugs with propofol to assess haemodynamic and recovery profile of either combination. Objective-To evaluate quality and compare haemodynamic variability of anaesthesia among the patients scheduled for short surgical procedures in ketamine-propofol and fentanyl-propofol groups.

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Section: Discussionmentioning

confidence: 70%

Section: Discussionmentioning

confidence: 78%

Section: Discussionmentioning

confidence: 82%

Section: Discussionmentioning

confidence: 87%

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A Comparative Evaluation of Ketamine-Propofol Versus Fentanyl-Propofol in Total Intravenous Anaesthesia- A Double Blind Randomised Clinical Trial

Pandey¹,

Gupta²,

Choudhary³

et al. 2017

jemds

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“…The combina on has the less adverse effects than the either drug alone due to their complementary effects of 4 lowering the dose of both drugs. Ketamine is a strong analgesic which effec vely reduces the injec on pain of 14 propofol by a enua ng the afferent pain pathways.…”

Section: Discussionmentioning

confidence: 99%

Comparison of Anesthetic Properties of Ketofol (Ketamine with Propofol) and Propofol in Minor Surgical Procedures

Karki

Rajbanshi

Arjyal

et al. 2018

Birat J. Health Sci.

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Introduction: Outpatient anesthesia for the minor day care surgical procedures requires a safe anesthesia and anesthetic agents. For this purpose two study solutions propofol with ketamine (ketofol) and propofol were compared. The comparison of the both agents were assessed, evaluated and discussed in this study. Methodology: This is prospective study of 100 adult patients of both sex aged between 18-60 years with ASA physical status class I and II who were operated in the Birat Medical College teaching hospital. This study was started after approval from the ethical committee of the hospital and after written and informed consent from all participants. All patients were randomly divided into two groups. Group A (n=50) received ketamine with propofol and Group B (n=50) propofol after intravenous sedation with 2 mg of midazolam and 1 mg of butorphanol. The main aim of this study was comparison of onset of sedation, respiratory and cardiac adverse events, level of sedation using Ramsey sedation scale, requirement of sedatives, recovery time, average cost of the sedatives and postoperative complications between the two groups. All collected data are analyzed using MS Excel office 2007 and for the data analysis IBM SPSS software was used.Results: In the both groups patients were comfortable with the either anesthetic agents. Onset of anesthesia was faster in Group A. Intraoperative sedation was measured using Ramsay sedation scale and was comparable. Recovery from sedation was assessed with AVPU scale and patient was shifted to postoperative room after the verbal response. Postoperative complications seen were nausea vomiting, severe pain, ketamine induced psychotomimetic effects and all of these were treated well and discharged on the same day from the hospital.Conclusion: The combination of ketamine and propofol for the sedation in minor surgical procedures has more advantages than the propofol alone. The combination is cost effective, has better sedation and hemodynamic stability, quick recovery and fewer side effects in the post operative room. Birat Journal of Health SciencesVol.2/No.3/Issue 4/Sep- Dec 2017, Page: 287- 291

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Ketamine: Current applications in anesthesia, pain, and critical care

2014

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Ketamine was introduced commercially in 1970 with the manufacturer's description as a “rapidly acting, nonbarbiturate general anesthetic” and a suggestion that it would be useful for short procedures. With the help of its old unique pharmacological properties and newly found beneficial clinical properties, ketamine has survived the strong winds of time, and it currently has a wide variety of clinical applications. It's newly found neuroprotective, antiinflammatory and antitumor effects, and the finding of the usefulness of low dose ketamine regimens have helped to widen the clinical application profile of ketamine. The present article attempts to review the current useful applications of ketamine in anesthesia, pain and critical care. It is based on scientific evidence gathered from textbooks, journals, and electronic databases.

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Evaluation of Ketofol (Ketamine Propofol combination) as total intravenous anaesthetic for burn dressing in adult patient

Abstract: DOI: http://dx.doi.org/10.3329/jafmc.v8i1.13534 JAFMC Vol.8(1) 2012 pp.20-24

Cited by 4 publications

References 0 publications

A Comparative Evaluation of Ketamine-Propofol Versus Fentanyl-Propofol in Total Intravenous Anaesthesia- A Double Blind Randomised Clinical Trial

A Comparative Evaluation of Ketamine-Propofol Versus Fentanyl-Propofol in Total Intravenous Anaesthesia- A Double Blind Randomised Clinical Trial

Comparison of Anesthetic Properties of Ketofol (Ketamine with Propofol) and Propofol in Minor Surgical Procedures

Ketamine: Current applications in anesthesia, pain, and critical care

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