Evaluation of Intraoperative Brain Natriuretic Peptide as a Predictor of 1-Year Mortality After Liver Transplantation

Kim, Y.K.; Shin, Won-Jung; Song, Jae-Kwan; Kim, Y.; Kim, W.J.; Kim, S.-H.; Hwang, Gyu‐Sam

doi:10.1016/j.transproceed.2011.02.010

Cited by 18 publications

(23 citation statements)

References 38 publications

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“…All of the patients were subjected to our institutional standard anesthesia protocol for living donor liver transplantation 7-11. Briefly, anesthesia was induced with thiopental, fentanyl, midazolam and vecuronium, and was maintained using 1-2 vol% sevoflurane, 50% oxygen/air, and continuous infusion with vecuronium and fentanyl.…”

Section: Methodsmentioning

confidence: 99%

Is Stroke Volume Variation a Useful Preload Index in Liver Transplant Recipients? A Retrospective Analysis

Kim¹,

Hwang²,

Kim³

et al. 2013

Int. J. Med. Sci.

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Background: The right ventricular end-diastolic volume index (RVEDVI) is a good indicator of preload in patients undergoing liver transplantation. Although dynamic indices, such as stroke volume variation (SVV), have been used as reliable indicators in predicting fluid responsiveness, the evaluation of the relationship between SVV and direct preload status is limited. We investigated the relationship between SVV and RVEDVI, and tested the cutoff value of SVV to predict RVEDVI during liver transplantation.Methods: A total of 150 data pairs in 30 living donor liver transplant recipients were retrospectively investigated. Hemodynamic parameters, including SVV and RVEDVI were obtained from each patient at the 5 specific time points. Linear regression and receiver operating characteristic (ROC) curve analyses were performed.Results: The SVV significantly correlated with the RVEDVI (r = -0.616, P < 0.001). Cutoff values for the upper and lower tertiles of RVEDVI were 157 mL/m2 and 128 mL/m2, respectively. Tertile analysis indicated that upper tertile of RVEDVI had a significantly lower SVV than the middle tertile (median; 5% vs 8%, P < 0.05), and middle tertile of RVEDVI had a significantly lower SVV than the lower tertile (median; 8% vs 11%, P < 0.05). A 6% cutoff value of SVV estimated the upper tertile RVEDVI (>157 mL/m2) with the area under the curve of ROC curve of 0.832. A 9% cutoff value of SVV estimated the lower tertile RVEDVI (<128 mL/m2) with the area under the curve of ROC curve of 0.792.Conclusion: SVV may be a valuable estimator of RVEDVI in patients undergoing liver transplantation.

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Section: Methodsmentioning

confidence: 99%

Is Stroke Volume Variation a Useful Preload Index in Liver Transplant Recipients? A Retrospective Analysis

Kim¹,

Hwang²,

Kim³

et al. 2013

Int. J. Med. Sci.

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“…First of all, because "cirrhotic cardiomyopathy" is based on chronic liver disease, the Model for end-stage liver disease (MELD) score should be considered as predictive factor in liver [73]. However, the predictive value of MELD on the survival of liver transplantation is inconclusive [6,74,75].…”

Section: Prognosismentioning

confidence: 99%

“…BNP is thought to reflect cardiac dysfunction [74]. BNP concentrations correlate with cardiac function and hypertrophy [76] and seems to be the most sensitive index to identify subclinical asymptomatic left ventricular dysfunction [73].…”

Section: Prognosismentioning

confidence: 99%

Cirrhotic cardiomyopathy

and

Lee

2015

Cirrhosis: A Practical Guide to Management

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“…all-cause mortality, cardiac mortality, nonfatal myocardial infarction or coronary revascularisation. [36][37][38] The perioperative period is characterised by rapid haemodynamic changes and fluid shifts, all of which increase ventricular wall stress. While there is no doubt that myocardial ischaemia contributes to postoperative NP elevation, it is likely that perioperative haemodynamic changes are an important trigger for perioperative NP secretion, and not myocardial ischaemia alone.…”

Section: The Role Of Postoperative B-type Natriuretic Peptidementioning

confidence: 99%

Preoperative B-type natriuretic peptide risk stratification: do postoperative indices add value?

Rodseth

Vasconcellos²,

Naidoo

et al. 2013

Southern African Journal of Anaesthesia and Analgesia

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Evaluation of Intraoperative Brain Natriuretic Peptide as a Predictor of 1-Year Mortality After Liver Transplantation

Cited by 18 publications

References 38 publications

Is Stroke Volume Variation a Useful Preload Index in Liver Transplant Recipients? A Retrospective Analysis

Is Stroke Volume Variation a Useful Preload Index in Liver Transplant Recipients? A Retrospective Analysis

Cirrhotic cardiomyopathy

Preoperative B-type natriuretic peptide risk stratification: do postoperative indices add value?

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