Cirrhotic cardiomyopathy

Systolic and Diastolic Dysfunction in Patients With Cirrhosis

“…9 The pathogenesis of cardiac dysfunction in cirrhosis is poorly understood and is likely related to combination of factors that include impairment of stimulatory β-adrenergic receptor signalling pathways, altered plasma membrane physicochemical properties, and over activity of negativeinotropic factors such as nitric oxide, carbon monoxide and endocannabinoid systems. 12 The cardiac chamber evaluation showed higher LVDD and smaller LVSD in cirrhotics as compared to controls. However, in our study, indexed values of dimensions were not used and none of the patients had abnormal dimensions comparing to reference range as per American Society of Echocardiography recommendations.…”

Pattern of diastolic dysfunction in alcoholic and non-alcoholic cirrhotic portal hypertensive patients with or without ascites in rural population in South India

“…7,8 The term "cirrhotic cardiomyopathy" is generally defined by the following clinical criteria: (1) baseline increased cardiac output but blunted ventricular response to stimuli, (2) systolic and/or diastolic dysfunction, (3) absence of overt left ventricular failure at rest, and (4) electrophysiological abnormalities including prolonged QT interval on electrocardiography and chronotropic incompetence. [9][10][11] Many patients with cirrhosis exhibit various degrees of diastolic dysfunction. Diastolic relaxation is impaired in cirrhosis.…”

Correlation between QT-interval Duration and Treatment with Propranolol in Patients with Liver Cirrhosis

“…Electrophysiological abnormalities as prolonged QT-interval and chronotropic incompetence [1][2][3][4].…”