Evaluation of inductively coupled plasma emission spectrometry as an element-specific detector for supercritical fluid chromatography

Forbes, Kimberley A.; Vecchiarelli, Jodi F.; Uden, Peter C.; Barnes, Ramon M.

doi:10.1021/ac00217a025

Cited by 25 publications

(6 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As in the case of GC, SFC can be coupled to FID, MS, UV or fluorescence detectors. SFC-ICP system has been used for the separation and identification of a series of organosiloxanes [50].…”

Section: Chromatographic Methodsmentioning

confidence: 99%

A Primer on the Analytical Aspects of Silicones at Trace Levels-Challenges and Artifacts – A Review

2006

View full text Add to dashboard Cite

Silicones (polydimethylsiloxanes) find use in a wide variety of industrial and consumer product applications because of their outstanding properties. Potential human exposure to silicones occurs in the work place during manufacturing and product formulation, as well as through the normal use of consumer products containing them.The entry of silicones into various environmental compartments raised health and safety concerns from potential exposure and mandated numerous environmental and toxicological studies. Such studies require qualitative and quantitative determination of silicone species at trace levels. However, the ubiquitous presence of silicones coupled with their unique chemistry renders their analysis at trace levels challenging.This paper provides a consolidated account of various aspects of silicones that must be borne in mind to obtain reliable data. The following topics are discussed: differences in the chemistry of silicones vs carbon; precautions in sample handling to avoid losses and inadvertent chemical transformation; potential sources for artifacts and interferences that could lead to systematic errors and data misinterpretation; sources for background and the need for matrix matched blank experiments; distinguishing silicones from silicates to avoid overestimation; potential for incorrect structural assignments; preventing inadvertent contamination; and questionable claims on the presence of silicones in biological matrices including that of silicone implants.

show abstract

“…As in the case of GC, SFC can be coupled to FID, MS, UV or fluorescence detectors. SFC-ICP system has been used for the separation and identification of a series of organosiloxanes [50].…”

Section: Chromatographic Methodsmentioning

confidence: 99%

A Primer on the Analytical Aspects of Silicones at Trace Levels-Challenges and Artifacts – A Review

2006

View full text Add to dashboard Cite

show abstract

“…Indeed, SFC coupled to an atomic detector (ICP-OES) was achieved to separate various siloxanes with detection limit of 57.9 mg kg À1 of Si. 190 Excellent separation of PDMS with a molecular mass of 2000 g mol À1 has been reported by SFC-FID. 191 This method was applied with SFC/MS for the determination and the identification of cyclic siloxanes in technical silicon oils and rubbers.…”

Section: Supercritical Fluid Chromatography (Sfc)mentioning

confidence: 99%

Silicon speciation by hyphenated techniques for environmental, biological and industrial issues: A review

Chainet

Lienemann

Courtiade

et al. 2011

J. Anal. At. Spectrom.

View full text Add to dashboard Cite

Silicon speciation in environmental, biological and industrial matrices is of considerable importance due to its wide use in many consumer and personal care products and industry. In addition, the entry of silicones in various compartments like wastes, soils, air and water highlights the need to perform exposure studies, toxicological surveys and to measure negative effects. Due to possible contamination and trace level presence of silicon compounds, challenges to determination, identification and quantification are presented. The principal species of concern include siloxanes, silanols, silanediols and silanes. State of the art of analytical methods for total silicon determination and silicon speciation are established. Atomic spectroscopic methods are mainly used to measure total Si at trace concentration levels. On the opposite, hyphenated techniques are performed for Si speciation. Particular attention is paid to chromatographic methods coupled to sensitive and selective detectors (MS, AED and ICP) allowing structural information. Liquid and gas chromatography emerge as the most widespread separation techniques. However, other procedures such as MS, NMR, IR and XRF enable a better knowledge of these species. The potential and limitations of hyphenated techniques are highlighted, particularly concerning sensitivity and selectivity. Furthermore, potential sources of contamination and analytical artifacts in silicon determination are reviewed.

show abstract

“…Successful capillary SFC interfaces have been devised for ICP using direct injection [53], with a SWP [54] and with a Beenakker MIP using a toroidal plasma sustained in an ICP type torch with auxiliary argon flow gas [MI.…”

Section: Liquid Chromatographsmentioning

confidence: 99%

Evaluation of inductively coupled plasma emission spectrometry as an element-specific detector for supercritical fluid chromatography

Cited by 25 publications

References 31 publications

A Primer on the Analytical Aspects of Silicones at Trace Levels-Challenges and Artifacts – A Review

A Primer on the Analytical Aspects of Silicones at Trace Levels-Challenges and Artifacts – A Review

Silicon speciation by hyphenated techniques for environmental, biological and industrial issues: A review

Determination of trace elements by chromatographic methods employing atomic plasma emission spectroscopic detection

Contact Info

Product

Resources

About