Three herbicides, namely Pendimethalin, Trifluralin and Terbutryn were used to control the Italian ryegrass (Lolium multiflorum) associated with barley (Hordeum vulgare). The first herbicide Pendimethalin gave an effective control of L. multiflorum at doses as low as .125 kg a.i/ ha and few plants survived with rates 0.5 kg a.i/ha. Effects on barley were severe; at dose of 0.25 kg a.i/ha barley plants decreased by more than 50%. Trifluralin controlled ryegrass numbers up to 90% at 1 kg/ha and caused little damage to barley plants. The last herbicide Terbutryn decreased the numbers of ryegrass plants quite effectively; it also damaged barley plants even at very low doses. ª 2014 Production and hosting by Elsevier B.V. on behalf of Faculty of Agriculture, Ain Shams University.