Evaluation of heat treatment regimes and their influences on the properties of powder‐printed high‐density polyethylene bone implant

Suwanprateeb, Jintamai; Kerdsook, Somrudee; Boonsiri, Tanyarat; Pratumpong, Patcharee

doi:10.1002/pi.3006

Cited by 22 publications

(4 citation statements)

References 36 publications

(45 reference statements)

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“…The heat treatment time and temperature variation (time: 15-60 min and temperature: 140 °C-180 °C) effect on the properties in both heating steps were studied. The primary heat treatment at 180 °C for 15 min and the second step heat treatment at 160 °C for 60 min generated the scaffold with the highest tensile modulus (Suwanprateeb et al 2011).…”

Section: Synthetic Polymersmentioning

confidence: 99%

Biomaterials in bone and mineralized tissue engineering using 3D printing and bioprinting technologies

Rahimnejad¹,

Rezvaninejad²,

Rezvaninejad³

et al. 2021

Biomed. Phys. Eng. Express

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This review focuses on recently developed printable biomaterials for bone and mineralized tissue engineering. 3D printing or bioprinting is an advanced technology to design and fabricate complex functional 3D scaffolds, mimicking native tissue for in vivo applications. We categorized the biomaterials into two main classes: 3D printing and bioprinting. Various biomaterials, including natural, synthetic biopolymers and their composites, have been studied. Biomaterial inks or bioinks used for bone and mineralized tissue regeneration include hydrogels loaded with minerals or bioceramics, cells, and growth factors. In 3D printing, the scaffold is created by acellular biomaterials (biomaterial inks), while in 3D bioprinting, cell-laden hydrogels (bioinks) are used. Two main classes of bioceramics, including bioactive and bioinert ceramics, are reviewed. Bioceramics incorporation provides osteoconductive properties and induces bone formation. Each biopolymer and mineral have its advantages and limitations. Each component of these composite biomaterials provides specific properties, and their combination can ameliorate the mechanical properties, bioactivity, or biological integration of the 3D printed scaffold. Present challenges and future approaches to address them are also discussed.

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Section: Synthetic Polymersmentioning

confidence: 99%

Biomaterials in bone and mineralized tissue engineering using 3D printing and bioprinting technologies

Rahimnejad¹,

Rezvaninejad²,

Rezvaninejad³

et al. 2021

Biomed. Phys. Eng. Express

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“…The intrinsic properties strongly influence processibility of UHMWPE in AM routes. These properties include particle shape, size, size distribution, morphology, powder flowability, and crystallization [272]. It has been observed that at the initial stage, UHMWPE possesses a spherical particle shape, known as 'potato shape', which is believed to assist in polymer printability via powder printing strategies [271].…”

Section: Additive Manufacturingmentioning

confidence: 99%

“…While there are no reports on using this technique for UHMWPE, but some information is available for 3D printing of HDPE. Suwanprateeb et al varied the amount of starch in HDPE and observed that an increase in starch amount resulted in scaffolds with impaired mechanical properties [272,273]. We postulate that the bottleneck in implementing this technique is PE’s chemical inertness, which restricts its interaction with the commonly used binders.…”

Section: Emerging Opportunitiesmentioning

confidence: 99%

Six decades of UHMWPE in reconstructive surgery

Chowdhury

Keshavan

Basu

2022

International Materials Reviews

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Ultra-high molecular weight polyethylene (UHMWPE) materials have played a significant role in the field of reconstructive surgery, particularly as acetabular liners/sockets for total hip joint replacement (THR), and tibial inserts for total knee joint replacement (TKR). This review aims to provide a perspective on key elements regarding the processing-structure-property relationship of UHMWPE and derivatives. Much emphasis will be provided to discuss the clinically relevant properties of UHMWPE blend/composite formulation, Vitamin-E reinforced or highly crosslinked variants. In addition, we provide clinical insights into the role of wear debris in inflammation and osteolysis. The relatively unexplored domain of UHMWPE additive manufacturing. Finally, the relatively unexplored domain of UHMWPE additive manufacturing and the opportunities associated with the next generation of UHMWPE implants are highlighted.

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“…This would lead to high control over the pore size and interconnectivity on each cross section and makes it possible to have gradually porous, hierarchical 3D structures. [46] Generally, 3D printing benefits are high control over the structure and porosity, repeatability, wide range of printable material choice (including natural and synthetic polymers, [169][170][171] ceramics, [172,173] metals, [174,175] and composites [46,176] ), and method's simplicity. Because the processing time is relatively short, the term "rapid prototyping" is assigned to 3D printing methods as well.…”

Section: D Printingmentioning

confidence: 99%

(Bio)manufactured Solutions for Treatment of Bone Defects with an Emphasis on US‐FDA Regulatory Science Perspective

Ghelich

Kazemzadeh-Narbat²,

Najafabadi

et al. 2022

Advanced NanoBiomed Research

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With a global prevalence of more than 2 million graft procedures per year, bone grafts are one of the most common transplants. [1][2][3][4][5] Small bone defects can be restored naturally, while large defects created by severe trauma, accidents, or tissue resection are unable to heal on their own. [6] As a rigid organ in humans and live animals, bone supports and protects different organs, tissues, and facilitates the mobility of the body. [7,8] These unique applications of bone are mainly attributed to the hierarchical architecture of bone, which mainly consists of the soft collagen protein and stiffer apatite mineral. [9] The overall stiffness of bone is primarily controlled by the natural mineral content as well as collagen to mineral ratio. [7,10] The mechanism of bone regeneration can be categorized as direct or indirect healing. [11] The size of fracture is one of the important factors that affects the bone healing mechanism. Direct bone healing mainly starts when a small and narrow (≤0.1 mm) fracture occurs, and the site of a fracture is rigidly stabilized. During direct bone healing, the small gap is covered directly by continuous ossification, following Haversian remodeling in a serial order. [12] Larger defects mostly heal by the indirect bone healing via various parallel events, such as blood clotting, inflammatory response, fibrocartilage callus formation, intramembranous and endochondral ossification, and results in bone remodeling. [11,12] A critical size defect is defined as the minimum defect dimension which is incapable of repairing without intervention. Per Food and Drug Administration (FDA) recognized standard ASTM F2721, in a critical size defect, the length of defect is at least 1.5-2 times the diameter of the selected bone. Critically sized defects can overwhelm the tissue regeneration capacity and lead to permanent disabilities. [13,14] Thus, surgical interventions are needed for the treatment of critically sized defects (Figure 1).Bone mimetic grafts, with hierarchical structure, and effective functionality could be engineered by merging suitable biomaterials, [7] cells, [15] and bioactive agents. [16] To design biomimetic bone scaffolds, a combination of nano-/microtechnologies with macrotechnologies is required. [17] Although many technologies have been developed for bone tissue engineering incorporating

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Evaluation of heat treatment regimes and their influences on the properties of powder‐printed high‐density polyethylene bone implant

Cited by 22 publications

References 36 publications

Biomaterials in bone and mineralized tissue engineering using 3D printing and bioprinting technologies

Biomaterials in bone and mineralized tissue engineering using 3D printing and bioprinting technologies

Six decades of UHMWPE in reconstructive surgery

(Bio)manufactured Solutions for Treatment of Bone Defects with an Emphasis on US‐FDA Regulatory Science Perspective

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