Evaluation of genotoxic and oxidative stress response to dimethoate in freshwater fish <i>Channa punctatus</i> (Bloch)

Ali, Daoud; Kumar, Phool Gend; Kumar, Sudhir; Ahmed, Mukhtar

doi:10.1080/09542299.2014.11073965

Cited by 29 publications

(10 citation statements)

References 27 publications

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“…The decrease in MN formation observed after day 7 with doses of 4.52 and 11.30 mg/L NPK and after day 14 for 2.26 mg/L NPK may be attributed to the repair of damaged cells. Similar repair mechanisms have been reported in freshwater fish species exposed to different toxicants (Ali et al 2014;Ismail et al 2018;Nwani et al 2017).…”

Section: Discussionsupporting

confidence: 82%

“…The MN assay is preferred to other sensitive assays because it does not require killing of the fish specimen (Kumar et al 2013; Nwani et al 2014). It is also simple, rapid, consistent, and takes minimal time to complete (Ali et al 2014; Ajima et al 2020). Durgo et al (2009) observed free radical formation and significant DNA damage in human leucocytes exposed to wastewater from fertilizer factories.…”

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confidence: 99%

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Genotoxicity and Oxidative Stress Evaluations in Juvenile African Catfish Clarias gariepinus Exposed to NPK Fertilizer

et al. 2020

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Juvenile African Catfish (also known as Sharptooth Catfish) Clarias gariepinus were exposed to 2.26, 4.52, and 11.30 mg/L NPK (15-15-15) fertilizer for 21 d followed by 7 d of recovery to assess the genotoxic effects of the fertilizer in erythrocytes. Biomarkers of oxidative stress were evaluated in the liver and gill tissues. The fertilizer induced micronuclei formation with maximum effects on day 7 in erythrocytes of individuals that were exposed to 4.52 and 11.30 mg/L NPK, and on day 14 in individuals exposed to 2.26 mg/L of the same fertilizer. The lipid peroxidation, glutathione reductase, and reduced glutathione values in the exposed fish increased, while the values of catalase, superoxide dismutase, and glutathione peroxidase decreased. There were mixed trends in the recovery patterns after the 7-d withdrawal from the fertilizer. Careful use of the fertilizer in the field is recommended to avoid toxicological effects on nontarget organisms.

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Section: Discussionsupporting

confidence: 82%

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confidence: 99%

Genotoxicity and Oxidative Stress Evaluations in Juvenile African Catfish Clarias gariepinus Exposed to NPK Fertilizer

et al. 2020

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“…DNA damage was also observed in the gill cells of the European eel (Anguilla anguilla) exposed to the OP glyphosate (Guilherme et al 2012). Ali et al (2014) also reported the time-dependent and dose-dependent increase of genotoxicity of an OP insecticide, dimethoate in C. punctatus, which were found to be highly correlated with oxidative stress. Our results along with those of Pamanji et al (2015) mentioned earlier, provide information on the toxic effects of MCP in both the adults and embryos of zebrafish suggesting that MCP can affect zebrafish at any time during its life cycle.…”

Section: Discussionmentioning

confidence: 75%

Induction of DNA damage in the peripheral blood of zebrafish (Danio rerio) by an agricultural organophosphate pesticide, monocrotophos

et al. 2018

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The use of organophosphate pesticides (OPs) in agricultural practices in India has gained popularity due to their broad spectrum, low cost and high potency. Monocrotophos (an OP) which is a systemic and contact broad-spectrum cholinesterase inhibitor is being widely used in India. However, its use entails the damage to other non-target organisms such as fish. In the present study, zebrafish (Danio rerio) were exposed to various doses of monocrotophos (0.125, 0.625 and 1.25 lL/L) and genotoxicity studies were carried out employing the comet assay and micronucleus test in the peripheral blood of these fish after 24, 48 and 72 h of exposure. Significant DNA damage in the form of % tail DNA and micronuclei was observed in all the treated fish compared to the control. Both % tail DNA and micronuclei frequency were found to increase significantly as the concentration increased. DNA damage was also observed at all the time intervals for all treatments except in the 0.125 lL/L-treated group. A positive correlation was also observed between the comet assay and micronucleus test. The study thus suggests the use of zebrafish as an experimental model to study the genotoxic effects of agricultural pesticides using the comet assay and micronucleus test.

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“…Several studies have found a direct relationship between the occurrence of lipid peroxidation (LPO) and DNA damage expressed as MN presence (Ali et al 2014 ; Nwani et al 2010 ). In the present study, the occurrence of lipid peroxidation and liver histopathological alterations were observed in A. gr.…”

Section: Discussionmentioning

confidence: 99%

Using genotoxic and haematological biomarkers as an evidence of environmental contamination in the Ocoa River native fish, Villavicencio—Meta, Colombia

2016

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The studies evaluating the impact of environmental pollution on aquatic organisms have had a growing concern in recent decades. The Ocoa River runs through Villavicencio city, receiving the wastewater produced in the city. To date studies reporting the effect and the consequences of Ocoa River pollution on aquatic organisms inhabiting this water body are unknown. Haematological and genotoxicity biomarkers were evaluated in peripheral blood of two native fish species Astyanax gr. bimaculatus and Aequidens metae during rainy and dry season at three different sites of Ocoa River called Nacimiento (site 1, before entering the city), Centauros (site 2, inside the city), Caño Seco (site 3, after the city). Also, fish from a reference site with little likelihood of contamination were sampled. Alterations such as decrease in erythrocyte count, lymphocytes, haemoglobin concentration and haematocrit percentage, and increased thrombocytes and neutrophils counts, together with nuclear abnormalities in erythrocytes such as increased frequency of micronuclei, lobed, blebbed and notched nuclei and binucleate cells were observed in fish from the site 3, followed by the site 2 in rainy season. These results shown that during rainy season, sites 2 and 3 receive domestic and industrial wastewater leading to genotoxic and haematological changes in the monitored organisms.Electronic supplementary materialThe online version of this article (doi:10.1186/s40064-016-1753-0) contains supplementary material, which is available to authorized users.

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Evaluation of genotoxic and oxidative stress response to dimethoate in freshwater fish Channa punctatus (Bloch)

Cited by 29 publications

References 27 publications

Genotoxicity and Oxidative Stress Evaluations in Juvenile African Catfish Clarias gariepinus Exposed to NPK Fertilizer

Genotoxicity and Oxidative Stress Evaluations in Juvenile African Catfish Clarias gariepinus Exposed to NPK Fertilizer

Induction of DNA damage in the peripheral blood of zebrafish (Danio rerio) by an agricultural organophosphate pesticide, monocrotophos

Using genotoxic and haematological biomarkers as an evidence of environmental contamination in the Ocoa River native fish, Villavicencio—Meta, Colombia

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