Evaluation of Gastroprotective Effect of Coenzyme Q 10 and L - Glutamine in Stress and Ethanol-Induced Peptic Ulcer in Wistar Rats: A Novel Preclinical Study
Abstract:Objective: Coenzyme Q 10 (CoQ10) and L-glutamine have antioxidant property their role in peptic ulcer diseases is not well known. Hence, the aim of present study is to evaluate the gastroprotective role of CoQ10 and L-glutamine in stress and ethanol-induced peptic ulcers in Wistar albino rats.Methods: A total of 90 rats were used for the conduct of study in two experimental models, the stress- and the ethanol-induced ulcer model. Each model consists of eight groups with six rats in each group. Sucralfate and p… Show more
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