Evaluation of functional dynamics during osseointegration and regeneration associated with oral implants

Abstract

Objectives-The aim of this paper is to review current investigations on functional assessments of osseointegration and assess correlations to the peri-implant structure.Material and methods-The literature was electronically searched for studies of promoting dental implant osseointegration, functional assessments of implant stability, and finite element (FE) analyses in the field of implant dentistry, and any references regarding biological events during osseointegration were also cited as background information.Results-Osseointegration involves a cascade of protein and cell apposition, vascular invasion, de novo bone formation and maturation to achieve the primary and secondary dental implant stability. This process may be accelerated by alteration of the implant surface roughness, developing a biomimetric interface, or local delivery of growth-promoting factors. The current available preclinical and clinical biomechanical assessments demonstrated a variety of correlations to the peri-implant structural parameters, and functionally integrated peri-implant structure through FE optimization can offer strong correlation to the interfacial biomechanics.Conclusions-The progression of osseointegration may be accelerated by alteration of the implant interface as well as growth factor applications, and functional integration of peri-implant structure may be feasible to predict the implant function during osseointegration. More research in this field is still needed.

High-frequency loading positively impacts titanium implant osseointegration in impaired bone

“…These are important in evaluating the properties (e.g., strength) of the tissue surrounding the implant. Secondly, the provided data of the present study (as well as of recent studies from other groups) offer descriptive findings, whereas further exploration of the mechanistic links between HF loading and implant osseointegration is still lacking [50]. Furthermore, given the facts that no power analysis was performed and that the use of the three-way interaction model implicated the assessment of statistical differences in several subgroups, the results of the non-significant outcomes should be interpreted cautiously.…”

Implant Stability - Measuring Devices and Randomized Clinical Trial for ISQ Value Change Pattern Measured from Two Different Directions by Magnetic RFA

“…Therefore, the general loading capacity of the interface (or interfacial shear strength) can be measured by dividing the maximum force by the area of implant in contact with the host bone (Berzins, et al 1997). However, the push-out and pull-out tests are only applicable for non-threaded cylinder type implants, whereas most of clinically available fixtures are of threaded design, and their interfacial failures are solely dependent on shear stress without any consideration for either tensile or compressive stresses (Brunski, et al 2000, Chang, et al 2010 (Fig. 1b-c).…”

Insertion Torque Function Analysis of Novel Dental Implant Geometry

“…Secondary stability measurements start after weeks of the implant insertion. The following main parameters influence the secondary stability: dental implant base material, type of the surface modification, bone regeneration ability, the state of health of the individual [2,3].…”