The present work is to investigated the effect of sodium chloride (NaCl) on the behavior of semi-arid soils in the Najran region of Saudi Arabia. An experiment work was carried out to investigate how the addition of (NaCl) "salt" to semi-arid soils collected from Najran region affects the Atterberg limits, compaction characteristics, California Bearing Ratio (CBR) and shear strength. All tests were performed on soils samples collected from different areas in Najran region at various depths of 1.5, 3, and 4.5 m along soil profiles. Soils samples were tested alone and then compared with the same soils samples mixed with sodium chloride (salt) at different percentages of 5, 10, and 20% respectively. Using advanced techniques, such as the scanning electron microscope (SEM), energy dispersive x-ray analysis (EDX) and X-ray diffraction analysis (XRD), the process of stabilization was examined. The results showed that salt has a major impact on the geotechnical characteristics of semi-arid soils. With the addition of sodium chloride, the maximum dry density increased and the optimal water content decreased with the increase in the added salt percentage. The liquid and plastic limits and, in turn, plasticity index reduced as the added percentage of sodium chloride increased. Furthermore, significant increase in CBR and shear strength parameters was noticed. It is therefore concluded that, the sodium chloride could be a good stabilizing agent, particularly at 20% and could be used as a sub-base material in road construction. Technical and economic advantages arise from the implementation of NaCl.