Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestions

Öztürk, Barış; Tütüncü, Emin Ediz; Kuşçu, Ferit; Gürbüz, Yunus; Şencan, İrfan; Tüzün, Hakan

doi:10.1016/j.ijid.2011.06.005

Cited by 38 publications

(39 citation statements)

References 12 publications

(23 reference statements)

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“…Even though the CRP level is not usually elevated in viral diseases, an elevated CRP level has been reported in some viral diseases (17). It has also been reported that the CRP level is higher in fatal cases than in non-fatal ones in CCHF (15,18). Similarly, in our study, the CRP level was high in all patients, but it was higher in fatal than in non-fatal patients.…”

Section: Discussionsupporting

confidence: 61%

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Procalcitonin Level and Its Predictive Effect on Mortality in Crimean-Congo Hemorrhagic Fever Patients

Gül

Öztürk²,

Kısa

et al. 2015

Jpn J Infect Dis

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SUMMARY: Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal disease which is endemic to Turkey. We aimed to investigate the procalcitonin levels and their prognostic value over fatality in CCHF patients. The sera were harvested from patients who were diagnosed with CCHF within the first 2 days of the onset of their symptoms. The patients were divided into 2 groups according to their survival status: fatal or non-fatal. The biochemical and hematological parameters were studied in the Biochemistry Laboratory of Sorgun City Hospital. The sera were stored at -809 C until testing for procalcitonin, and the procalcitonin levels were assayed by ELISA at the Biochemistry Laboratory of Kirikkale University. Forty-eight patients were included in the study, with 8 and 40 patients in the fatal and non-fatal groups, respectively. While the procalcitonin level was high in all patients in the fatal group, the same was observed in 30 patients in the non-fatal group (75z). The mean value of procalcitonin was 1.12 ng/ml in the fatal group and was 0.21 ng/ml in the non-fatal group (P ＝ 0.003). According to the results of our study, the procalcitonin levels in the first 2 days of the onset of the symptoms might be helpful for predicting fatality in CCHF patients.

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Section: Discussionsupporting

confidence: 61%

“…Elevated liver enzymes, prolonged bleeding time, and decreased platelet and leukocyte levels have been observed in many studies (11)(12)(13)(14)(15). In most of these studies, majority of these parameters were found to be related to the prognosis.…”

Section: Discussionmentioning

confidence: 98%

Procalcitonin Level and Its Predictive Effect on Mortality in Crimean-Congo Hemorrhagic Fever Patients

Gül

Öztürk²,

Kısa

et al. 2015

Jpn J Infect Dis

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“…With the first patient, who was the first losing her baby, we noticed that she had hypotension and very low levels of fibrinogen [12]. Maybe low levels of fibrinogen are prognostic factors, especially in hemorrhagic fever of Crime-Congo [13].…”

Section: Discussionmentioning

confidence: 96%

Hemorrhagic Fevers with Renal Syndrome Presenting with Pregnancy Interruption

Qyra¹,

Puca²,

Harxhi³

et al. 2017

Journal of Microbiology and Infectious Diseases

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Hemorrhagic fever with renal syndrome is presented with so many different clinical symptoms. It can present mild form of the disease or the severe symptoms. We reported two cases with HFRS, at pregnant women, ended with pregnancy interruption. Both of them had nearly the same age, both 16 weeks pregnant. They presented with fever, malaise, muscle pain and headache. They were febrile when presented at the hospital, hypotensive, hyperemia on the face. They complained about oligo-anuria too. One of them continued to be hypotension, despite the supportive therapy she had an abortion after 8 hours. The other patient had the abortion on the 4 th day of hospitalization. The diagnose was set based on the clinical, epidemiological findings and the serological positive confirmation for IgM Hantavirus by enzyme-linked immunosorbent assay and immunofluorescence assay IFA.The abortion is a rare complication of HFRS in pregnancy. The symptoms are not specific. Early diagnosis and appropriate management are necessary to improve the maternal and fetal outcome. J Microbiol Infect Dis 2017; 7(4):198-201

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“…KKKA'nın tipik laboratuvar bulguları, trombositopeni, lökopeni, aspartat aminotransferaz (AST), alanin aminotransferaz (ALT), kreatin kinaz (CK) ve laktat dehidrogenaz (LDH) düzeylerinin yükselmesidir (6,7). Hastamızda ilk günkü hemogram, AST, ALT, LDH ve CK değerleri normal sınırlar-daydı.…”

Section: İrdelemeunclassified

“…KKKA'da tanı, hastamızda da olduğu gibi, özgül IgM ve IgG antikorlarının PCR ile saptanmasıyla konulmaktadır (6,8).…”

Section: İrdelemeunclassified

Crimean-Congo Hemorrhagic Fever Presented With Headache: A Case Report

Öcal¹,

Delikan²,

Cebi³

et al. 2015

Klimik Dergisi

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Evaluation of factors predictive of the prognosis in Crimean-Congo hemorrhagic fever: new suggestions

Abstract: It is essential to determine the possibility of a fatal prognosis in CCHF patients using clinical history and biochemical parameters so that the necessary precautions can be taken.

Cited by 38 publications

References 12 publications

Procalcitonin Level and Its Predictive Effect on Mortality in Crimean-Congo Hemorrhagic Fever Patients

Procalcitonin Level and Its Predictive Effect on Mortality in Crimean-Congo Hemorrhagic Fever Patients

Hemorrhagic Fevers with Renal Syndrome Presenting with Pregnancy Interruption

Crimean-Congo Hemorrhagic Fever Presented With Headache: A Case Report

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