Evaluation of energy spectrum CT for the measurement of thyroid iodine content

Abstract

BackgroundThis study aims to provide a reference for the diagnosis of iodine deficiency disorder by evaluating the normal thyroid iodine content by energy spectrum computed tomography (CT) and calculating the iodine content ratio of thyroid to sternocleidomastoid.MethodsThe thyroid glands of 226 patients were scanned by energy spectrum CT, and the images were analyzed using the GSI Viewer software. Based on the imaging findings, the iodine levels of the thyroid lobes as well as the bilateral sternocleidomastoids were evaluated, and their iodine content ratios were calculated.ResultsNo statistically significant difference was found in the thyroid iodine content between the left and right thyroid lobes (p > 0.05). However, there was a significant difference in the thyroid iodine content between men and women (p < 0.01). Additionally, the thyroid iodine content was found to decrease gradually with age. The iodine content ratio of thyroid to sternocleidomastoid was 96.6271 ± 33.2442.ConclusionGemstone energy spectrum CT can be used for the measurement of thyroid iodine content in the human body. It can play a significant role in the diagnosis of iodine deficiency disorder.

Iodine concentration and content measured by dual-source computed tomography are correlated to thyroid hormone levels in euthyroid patients: a cross-sectional study in China

“…The mean iodine concentration in the thyroid gland with normal thyroid function in the population was 1.31 ± 0.46 mg/ml, which was similar to that of 1.49 ± 0.41 mg/ml measured by gemstone energy spectrum CT imaging technology by Shao Weiguang [5] et al In this study, we found no correlation between thyroid volume and thyroid function. This may be because the thyroid volume can be affected by many factors, such as height, weight, etc.…”

“…Previous studies measuring the iodine concentration in phantom have shown that dual energy CT (DECT) is highly accurate in measuring the iodine concentration [3,4]. Shao Weiguang [5] and others proved that gemstone energy spectrum CT imaging made the measurement of iodine concentration more convenient, which can facilitate evaluations of thyroid function. Other studies have also confirmed that thyroid volume measured by CT is relatively accurate [6,7].…”

Iodine concentration and content measured by dual-source computed tomography are correlated to thyroid hormone levels in euthyroid patients

“…The mean iodine concentration in the thyroid gland with normal thyroid function in the population was 1.31±0.46 mg/ml, which was similar to that of 1.49±0.41 mg/ml measured by gemstone energy spectrum CT imaging technology by Shao Weiguang [5] et al In this study, we found no correlation between thyroid volume and thyroid function, which may be because the thyroid volume can be affected by many factors, such as height, weight, etc. [11.12] .…”

“…Previous studies measuring the iodine concentration in phantom have shown that dual energy CT (DECT) is highly accurate in measuring the iodine concentration [3.4] . Shao Weiguang [5] and others proved that gemstone energy spectrum CT imaging made the measurement of iodine concentration more convenient, which can facilitate evaluations of thyroid function. Other studies have also confirmed that thyroid volume measured by CT is relatively accurate [6.7] .…”

Utility of non-contrast Dual Energy Computed Tomography in diagnosis of differentiated thyroid cancer – two case study

“…SpCT tests without iodine contrast agent are not typically performed, so there are limited number of data available. Therefore some researchers tried to estimate iodine concentration in human thyroid tissue [17], or predict extrathyroidal extension and recurrence of PTC [18]. Moreover Bunch et al, in a retrospective study including 20 dual energy parathyroid computed topographies assessed the attenuation of thyroid tissue, parathyroid lesions, and sternocleidomastoid muscle [19].…”