Evaluation of efficacy of a commercially available herbal mouthwash on dental plaque and gingivitis: A double-blinded parallel randomized controlled trial

Bagchi, Sanjukta; Saha, Sabyasachi; Jagannath, G.V.; Reddy, Vinodini; Sinha, Pooja

doi:10.4103/2319-5932.165210

Cited by 16 publications

(14 citation statements)

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“…The present study attributed to substantivity property of Chlorhexidine for 12hours which is considered to be highly effective, whereas the substantivity of herbal mouth rinse is yet to be established. The findings of our study can be correlated with the findings of Bhate D et al 14 & Bagchi et al 17 who demonstrated Chlorhexidine to be a highly acceptable antiplaque agent. The findings of our study can be attributed to the presence of Terminalia chebula mouthwash to reduce plaque deposition in addition to its inhibition.…”

Section: Discussionsupporting

confidence: 91%

Comparative Evaluation of Efficacy of Hiora, Terminalia Chebula and Chlorhexidine as Mouth Wash on Dental Plaque

Gupta

Yadav

Khan

et al. 2017

JDHODT

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Introduction: Dental caries and periodontal diseases, the two arch criminals of oral cavity, are essentially caused by the microorganisms present in dental plaque. Aim and objectives: Evaluate the relative effectiveness of Chlorhexidine, Hiora, and T. chebula mouth rinses on plaque reduction. Materials and method: The present study was a randomized controlled crossover clinical trial. It was designed to evaluate and compare the efficacy of different mouth wash. Data obtained in relation to different assessing parameters at different phases of present study was subjected to statistical analysis using paired t-test. Results: Chlorhexidine was more effective in reducing dental plaque compare to other mouthwashes. Conclusion: Chlorhexidine shows better results compare to its herbal alternative but Hiora and Terminalia chebula mouthwash due to its natural ingredients has no reported side-effects and further studies with varied concentrations, different parameters and larger sample size are to be carried out to assess their efficacy of herbal mouthwash.

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Section: Discussionsupporting

confidence: 91%

Comparative Evaluation of Efficacy of Hiora, Terminalia Chebula and Chlorhexidine as Mouth Wash on Dental Plaque

Gupta

Yadav

Khan

et al. 2017

JDHODT

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“…[19][20][21] Our results also showed that these mouthwashes can be used as an additional plaque control technique along with mechanical method of plaque control these results were in contrast to the results obtained by Loe et al 22 despite its antibacterial properties, chlorhexidine has certain limitations in its use includes both teeth and tongue stains on its long-term use. 16 This study also has certain limitations.…”

Section: Discussioncontrasting

confidence: 56%

Comparison of the Antigingivitis and Antiplaque Efficacy of the Herbal Mouthwash With Allopathic Mouthwash: A Clinical Study

Aspalli¹,

Pal²,

Desai³

et al. 2018

Int. J. Res. Ayurveda Pharm.

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Introduction-Mouthwashes are often prescribed in dentistry for prevention and treatment of several oral conditions. Chlorhexidine gluconate mouthwash has earned eponym of gold standard to treat and/or prevent periodontal disease. In the recent times naturally occurring products are used on a large scale. Objective-The aim of this study is to compare the anti-gingivitis and antiplaque efficacy of herbal mouthwash (Hiora) with allopathic mouthwash (Chlorhexidine). Methodology-A total of 20 patients aged between 18 to 50 years, with gingivitis was selected for this study. After baseline scaling, 10 patients were advised to use 0.2% chlorhexidine mouthwash twice daily in 1:1 dilution and other 10 patients used Hiora mouthwash twice daily. Plaque index, gingival index, bleeding on probing was recorded at baseline and after 21 days. Result-There were no statistically significant differences between the two groups with regard to the clinical parameters. Herbal mouth rinses may be as effective as chlorhexidine as chemical antiplaque agents with fewer side effects Conclusion-Herbal mouth rinses may be as effective as chlorhexidine as chemical anti-plaque agents with fewer side effects. However, alternative study designs using larger sample sizes and longer duration are needed to further reiterate its benefits.

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“…Additional file 3: Table S3 summarizes the characteristics of the articles that were included in the meta-analysis. The most common preparation used was a solution containing 7% Salvadora persica extract [23, 25, 26, 29, 30, 32–34, 36, 41]. The studies were mostly performed in adult patients, up to 60 years old, whereas five studies were performed in children between the ages of 6 and 18 years [20–22, 27, 29, 36].…”

Section: Resultsmentioning

confidence: 99%

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of chlorhexidine: a systematic review and meta-analysis

2019

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Background The plant Salvadora persica (miswak) has a long history of use in oral hygiene. Associations between the use of Salvadora persica and decreased oral bacteria numbers and plaque scores have been reported. This systematic review and meta-analysis assessed the ability of Salvadora persica mouthrinses to reduce plaque/cariogenic bacteria, in comparison to that of chlorhexidine and/or placebo rinses. Methods A comprehensive literature search for clinical trials reporting the use of Salvadora persica rinses as an antibacterial and/or antiplaque agent in comparison with chlorhexidine and/or placebo rinses was conducted, with no restriction to language. MEDLINE-PubMed, Cochrane Central Register of Controlled Trials, Wiley Online Library, ScienceDirect, and Google Scholar databases were searched to include all articles published up to December 2018. Based on inclusion/exclusion criteria, data were extracted from the identified reports by two independent reviewers. The primary and secondary outcomes measured from the eligible studies were mean plaque scores and mean cariogenic bacterial counts, respectively. Risk of bias of these studies was assessed. A statistical test of homogeneity was used to determine if the results of the separate studies could be combined. Based on the chi-square test, an inconsistency coefficient was computed (I 2 statistic). Sensitivity analyses using subgroups and homogeneity evaluation were conducted. Results A total of 1135 potentially eligible articles were identified, of which 19 were eventually included in the qualitative analysis whereas 18 were included in the quantitative meta-analysis. The meta-analysis showed that Salvadora persica rinses exhibited strong antiplaque effects ( P < 0.00001, MD: 0.46, and 95% CI: 0.29 to 0.63). In addition, it had statistically significant anti-streptococcal ( P < 0.0001, MD: -1.42, and 95% CI: -2.08 to − 0.76) and anti-lactobacilli effects ( P < 0.00001, MD: -1.12, and 95% CI: -1.45 to − 0.79) when compared to placebo. However, its effects were inferior compared to those by chlorhexidine rinse ( P = 0.04, MD: 0.19, and 95% CI: 0.01 to 0.37). Subgroup analyses yielded results similar to those prior to subgrouping. Conclusion The use of Salvadora persica extract was associated with a significant reduction in the plaque score and cariogenic bacterial count. Although, this reduction was lower than that achieved with the gold standard chlorhexidine mouthwash, Salvadora persica -containing rinse could be considered as a suitable oral hygiene alternative for use in individuals of all ages, socioeconomic backgrounds, and health con...

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Evaluation of efficacy of a commercially available herbal mouthwash on dental plaque and gingivitis: A double-blinded parallel randomized controlled trial

Cited by 16 publications

References 0 publications

Comparative Evaluation of Efficacy of Hiora, Terminalia Chebula and Chlorhexidine as Mouth Wash on Dental Plaque

Comparative Evaluation of Efficacy of Hiora, Terminalia Chebula and Chlorhexidine as Mouth Wash on Dental Plaque

Comparison of the Antigingivitis and Antiplaque Efficacy of the Herbal Mouthwash With Allopathic Mouthwash: A Clinical Study

The antiplaque/anticariogenic efficacy of Salvadora persica (Miswak) mouthrinse in comparison to that of chlorhexidine: a systematic review and meta-analysis

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