Evaluation of disease occurrence and production parameters of dairy cows treated with pegbovigrastim

Abstract

Pegbovigrastim is a modified form of the naturally-occurring bovine granulocyte colony-stimulating factor. At the time of the study, pegbovigrastim was commercially available under veterinary prescription as Imrestor (Elanco Animal Health, Greenfield, Indiana). According to the product label, when the product is applied 7 days before calving and again at the day of calving, clinical mastitis incidence decreases by 28% in the first 30 days of lactation in dairy cows and heifers. The objective of this study was to further demonstrate the effectiveness of Imrestor at reducing clinical mastitis incidence, and to demonstrate the effectiveness at reducing metritis incidence in the first 30 days of lactation on a commercial dairy operation.