Evaluation of digitally guided fine needle aspiration cytology versus fine needle core biopsy for the diagnosis of recurrent rectal cancer

Wiig, Johan N.; Berner, Aasmund; Giercksky, Karl Erik

doi:10.1007/s003840050060

Cited by 6 publications

(2 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…If necessary, transrectal fine-needle aspiration cytology or fine-needle core biopsy was performed. In our hands cytology was more accurate than biopsy (Wiig et al 1996). Routine examinations before inclusion were digital recto-vaginal exploration, sigmoidoscopy with rigid instrument, CT of the pelvis (in recent years often MRI), ultrasound of the liver, chest X-ray, and blood tests including CEA.…”

Section: Methodsmentioning

confidence: 64%

Operative Treatment of Locally Recurrent Rectal Cancer

Wiig

Larsen

Giercksky

Recent Results in Cancer Research

View full text Add to dashboard Cite

Few centres with varying regimens have published studies including more than 100 patients on the treatment of locally recurrent rectal cancer. The results vary considerably. Thus there seems to be a need for more studies to establish the potential benefit of a more widespread treatment of these cancers. In total, 193 patients had surgery for locally recurrent rectal cancers after preoperative irradiation 46-50 Gy in 2 Gy fractions. The patients were followed up and the data prospectively entered in a database. In 88 patients with primary low anterior resection, 3% had lower end of tumour located more than 2 cm above the anastomosis, 5% more than 2 cm below the anastomosis; 13% had exploratory laparotomy, 8% low anterior resections, the rest equally frequent abdomino-perineal resections, Hartmann's operations, and tumour resections. Nearly half had resection of part of the pelvic wall. Hysterectomy was performed in 15% and cystoprostatectomy in 9%. Three patients had en bloc prostatectomy. R0 resections were achieved in 39%, R1 in 36%, and R2 or no resection in 25%. R0 stage was twice as often achieved after a primary low anterior resection as after abdomino-perineal resections. The 30-days postoperative mortality was 1%. Postoperative morbidity was 48%, most frequently pelvic abscesses. Estimated 5-year survival was 18% for the total group. There was a statistically significant difference in survival and local re-recurrences between R0 / R1 and R2 stages. The results are discussed relative to recent studies. Patients in whom R0 resections can be achieved will benefit from the treatment, and probably patients with R1 resections would also benefit. Such operations should possibly be performed in specialised centres as joint ventures between various surgical subspecialities.

show abstract

Section: Methodsmentioning

confidence: 64%

Operative Treatment of Locally Recurrent Rectal Cancer

Wiig

Larsen

Giercksky

Recent Results in Cancer Research

View full text Add to dashboard Cite

show abstract

“…Nach älteren Berichten über eine digitalassistierte Biopsie [26] wurden Erfahrungen mit der ultraschallgesteuerten Biopsie verdächtiger Läsionen erst von wenigen Autoren mitgeteilt: Bachmann Nielsen et al…”

unclassified

Die transrektale ultraschallassistierte Stanzbiopsie in der Diagnostik des präsakralen Rektumkarzinomrezidivs

Ommer

Pitt²,

Krause³

et al. 2004

Zentralbl Chir

View full text Add to dashboard Cite

Suspected extraluminal recurrence of rectal carcinoma after surgical treatment represents a frequent diagnostic challenge. Clinical history and examination as well as tomographic imaging often do not equivocally settle this tissue. Glucose-PET is an expensive, not universally available test. Early diagnosis is required for both successful operative reintervention aiming at cure and indication to palliative therapy. We performed gun-biopsy of presacral space-occupying lesions in three patients, choosing the ultrasound-guided transrectal approach in three of them. Extraluminal recurrence was proven in one patient. In another patient, anastomotic recurrence was proven by endoscopic biopsy and presacral recurrence ruled out before reoperation. In the third patient, no tumour tissue was found in the samples, as confirmed by his clinical course and by another biopsy after one year. By providing a sufficient amount of tissue for histological examination, ultrasound-guided gun-biopsy allows definite diagnosis in presacral space-occupying lesions and hence represents an important expansion of the diagnostic repertoire in the follow-up of rectal cancer.

show abstract