Evaluation of Different Bowel Preparations for the Study with Capsule Endoscopy: A Prospective, Randomized, Controlled Study

Evaluation of Different Bowel Preparations for Small Bowel Capsule Endoscopy: A Prospective, Randomized, Controlled Study

“…Preliminary results have already been published by our group [6]. Although similar studies exist (Table 6), none of the three abovementioned preparations have been compared in a randomized way, and have only been analysed in short series [5,7,8] or retrospectively [8].…”

Intestinal preparation prior to capsule endoscopy administration

“…Results such as those of Pons et al [13] and Lapalus et al [14] tilt the balance in favour of no prior preparation. Lapalus et al [14] compared the administration of aqueous sodium phosphate (ASP) vs clear liquids and did not observe any difference in the level of cleanliness or in visibility.…”

“…The results of the aforementioned Spanish group [13] are a fruit of a multi-centre, random, prospective study that compared the efficacy and tolerability of three different preparations applied prior to capsule endoscopy in a large sample of patients. Observers were blind to the type of preparation employed.…”

Capsule Endoscopy: A Comprehensive Review

“…It is recommended that patients avoid magnetic fields such as magnetic resonance imaging (MRI), and metal detectors until the capsule is excreted in the stool, which usually occurs in 24-48 h. Small bowel preparation is still a controversial issue. Some groups used fasting or clear liquids for 10 to 12 h (or even for 24 h) before the study, although some studies suggest that bowel preparation (with 2 or 4 liters of polyethylene glycol based electrolyte solution or oral sodium phosphate preparation) improves the visualization of the small intestine (Dai et al,2005;de Franchis et al,2005).A recent Spanish prospective multicenter trial published in abstract form, has shown that all three strategies have similar results (Pons et al,2006). After ingestion of the capsule, patients were allowed to drink clear liquids after 2 h and eat a light meal after 4 h and were observed for 8 h at the study site.…”