Evaluation of Dental Pulp Sensibility Tests in a Clinical Setting

Jespersen, James J.; Hellstein, John W.; Williamson, Anne E.; Johnson, William T.; Qian, Fang

doi:10.1016/j.joen.2013.11.009

Cited by 85 publications

(110 citation statements)

References 28 publications

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“…The most commonly used methods in clinical practice to determine pulp status are pulp sensibility tests, including the thermal test and EPT [13]. They are not directly related to pulpal vitality, but depend on a subjective response to an external stimulus to the nervous system [13–15].…”

Section: Discussionmentioning

confidence: 99%

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Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study

et al. 2017

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BackgroundExperiments have previously demonstrated the therapeutic potential of mobilized dental pulp stem cells (MDPSCs) for complete pulp regeneration. The aim of the present pilot clinical study is to assess the safety, potential efficacy, and feasibility of autologous transplantation of MDPSCs in pulpectomized teeth.MethodsFive patients with irreversible pulpitis were enrolled and monitored for up to 24 weeks following MDPSC transplantation. The MDPSCs were isolated from discarded teeth and expanded based on good manufacturing practice (GMP). The quality of the MDPSCs at passages 9 or 10 was ascertained by karyotype analyses. The MDPSCs were transplanted with granulocyte colony-stimulating factor (G-CSF) in atelocollagen into pulpectomized teeth.ResultsThe clinical and laboratory evaluations demonstrated no adverse events or toxicity. The electric pulp test (EPT) of the pulp at 4 weeks demonstrated a robust positive response. The signal intensity of magnetic resonance imaging (MRI) of the regenerated tissue in the root canal after 24 weeks was similar to that of normal dental pulp in the untreated control. Finally, cone beam computed tomography demonstrated functional dentin formation in three of the five patients.ConclusionsHuman MDPSCs are safe and efficacious for complete pulp regeneration in humans in this pilot clinical study.

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Section: Discussionmentioning

confidence: 99%

“…They are not directly related to pulpal vitality, but depend on a subjective response to an external stimulus to the nervous system [13–15]. The EPT can only be used to determine whether or not there is viable tissue in the root canal and cannot be used to determine the degree of pulp disease or vitality [16–18].…”

Section: Discussionmentioning

confidence: 99%

Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study

et al. 2017

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“…, Jespersen et al . ), although one study found that women expressed significantly lower electrical pain thresholds than men in maxillary central incisors with respect to pain modulation between the orofacial region and the spinal region (Rosen et al . ).…”

Section: Introductionmentioning

confidence: 99%

Effects of conducting media and gender on an electric pulp test

Chunhacheevachaloke

Ajcharanukul

2015

Int Endodontic J

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“…Endodontic diagnoses were made based on the guidelines set by the American Association of Endodontists (AAE) [10]. Clinical examination and testing were carried out on the tooth in question and its adjacent teeth using conventional methods [11] [12]. Cold, EPT (if no response to cold), percussion, palpation, probing and mobility assessment were performed.…”

Section: Introductionmentioning

confidence: 99%

Clinical Endodontic Applications of Cone Beam-Computed Tomography in Modern Dental Practice

Galicia¹,

Kawilarang²,

Tawil³

2017

OJST

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Nearly two decades since Cone Beam-Computed Tomography (CBCT) was introduced in dentistry, this technology has been proven to be a useful asset in modern dental practice. The information gleaned from a CBCT scan influences treatment decisions and prognostication of challenging endodontic cases. The authors present six cases that utilized CBCT to diagnose vertical root fracture, to assess resorption, to guide the clinician in overcoming anatomical complexities, to hurdle diagnostic dilemmas and to perform pre-surgical evaluation. Initially, a thorough clinical assessment was performed; however, conventional periapical radiographs were not able to provide sufficient information to arrive at a definite diagnosis or a thorough treatment plan. CBCT was therefore deemed helpful for these cases. Clearly, there are advantages to using CBCT. With a better understanding of each case, the clinician can plan a definitive treatment plan and offer a clearer case prognosis to their patient.

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Evaluation of Dental Pulp Sensibility Tests in a Clinical Setting

Cited by 85 publications

References 28 publications

Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study

Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study

Effects of conducting media and gender on an electric pulp test

Clinical Endodontic Applications of Cone Beam-Computed Tomography in Modern Dental Practice

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