Evaluation of dental material series from patients with dental prostheses and suspicion of delayed hypersensitivity

Abstract

BACKGROUNDPatients with oral sensitivity are common in our practice. Allergic contact dermatitis is one of the most frequent etiologies.OBJECTIVESEvaluate oral contact dermatitis using the Brazilian standard series and complementary dental series in patients using dental prostheses, with or without oral complaints. Determine specific dental Brazilian series.METHODSPatients using dental prostheses with or without oral complaints realized patch tests. Brazilian standard series and complementary dental series were used according to ICDRG recommendations. The results were analysed according to age, sex, race, atopic conditions and symptoms associated.RESULTSFrom 54 patients tested, 34 (63%) were positive at least to one substance. Nineteen had oral complaints, such as burning mouth, itch or oral erythema. There was no association between atopic condition and tests results. Without the oral series, just 23(42,6%) patients had a positive result. Using the Brazilian standard series with the complementary dental series we improved the positivity of the patch test to 47%.CONCLUSIONIn patients using prostheses and with oral complaints, patch tests with Brazilian standard series with complementary dental series improve the tests positivity.

Common Allergies and Allergens in Oral and Perioral Diseases

“…Gingivostomatitis is a disease of oral cavity that can also be associated with contact allergies after exposure to dental materials (e.g., metals or plastics in dentures), as it has been shown that stomatitis is associated with partial dentures and some dental metals (e.g., palladium, gold or manganese) ( Table 1) 7,39,40 . Gingivostomatitis as a reaction to acrylates is also possible (e.g., due to allergy to 2-hydroxyethyl methacrylate, HEMA, used in dentures).…”

Assessment of Allergies to Food and Additives in Patients with Angioedema, Burning Mouth Syndrome, Cheilitis, Gingivostomatitis, Oral Lichenoid Reactions, and Perioral Dermatitis

“…Most similar studies were focused on delayed hypersensitivity reactions in oral mucosal diseases by conducting patch tests 2,3,[11][12][13][14][15] , rather than by performing skin prick tests to detect immediate-type allergic reactions. What is more, previous research mainly investigated the role of contact allergens and inhalants in oral diseases, usually not determining common nutritive or additive allergens in oral and perioral diseases using skin prick tests [1][2][3] .…”

“…The key to getting an accurate diagnosis of allergy are skin patch and prick tests. Most of the previous studies were focused on delayed-type allergic reactions in oral diseases by performing patch testing but did not include tests for immediate-type reactions [1][2][3][10][11][12][13][14][15] . The objective of this study was to determine common nutritive and additive allergens in the prevalent oral and perioral diseases by using skin prick tests.…”

Reações alérgicas e suas manifestações na odontologia: revisão integrativa

“…Além disso, há o risco de sensibilização cruzada ao formaldeído. Yoshimura et al (2016) desenvolveram uma pesquisa em pacientes que faziam uso de próteses que possuíam alguma queixa e com indivíduos que não apresentaram queixa de alergia oral, onde 54 pacientes foram submetidos a testes de sensibilidade e 34 apresentaram sensibilidade a pelo menos uma substância de teste odontológico. Dos pacientes que se queixam de incômodos na cavidade oral, 68% apresentaram resultados positivos.…”

“…As reações do tipo I, também chamadas imediatas, na cavidade oral se manifestam como angioedema, sensação de ardor ou parestesia oral (Lugović-Mihić et al, 2020). As reações de hipersensibilidade tipo IV, também chamadas de tardia, são provocadas por haptenos e os sintomas para esse quadro são as reações liquenóides, eritema e estomatite (Yoshimura, 2016).…”