Evaluation of collagen type I scaffolds including gelatin-collagen microparticles and Aloe vera in a model of full-thickness skin wound

Gil-Cifuentes, Liliana; Jimenez, Ronald; Fontanilla, Marta R.

doi:10.1007/s13346-018-00595-x

Cited by 17 publications

(10 citation statements)

References 48 publications

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“…A scaffold used in autologous skin graft was based on collagen type I and modified with microparticles of gelatine-collagen type I, in order to evaluate the introduction of AV. The results were again not significant in terms of in vivo healing; however, as confirmation of the cross-linking issue, the observed decreased biodegradability of the material was associated with decreased in vitro enzyme degradation, that is, collagenase [ 148 ].…”

Section: Towards Therapeutic Application: Antioxidant Biomaterialsmentioning

confidence: 99%

“…Aloe vera (extract) [147,148] Caffeic acid [149,150] Calendula Officinalis [151] Cinnamaldhyde [152] Citric acid [153] Curcumin [154] EGCG [155] Ellagic acid [155] Equisetum arvense (extract) [156] Grape (pomace) [157] Lignin (kraft) [100] Ostholamide [158] Plumbagin [159] Resveratrol [160] Soybean (extract) [146] Tannic acid [131,155] Vitamin C [133].…”

Section: Scavenging Activitymentioning

confidence: 99%

“…Collagen [159] Collagen type I-Gelatin [148,151] Gelatin [153] Gelatin derivates-collagen [158] Gelatin-Hap [146] HA [160] P(3HB-co-3HV) [133] PCL [100,147] PCL-CH [149,150] PEG derivatives [155] PLA-derivates [152] PLA-Hap [156] PLGA [154] Porcine pericardium (decellularized) [157] Table 1. Cont.…”

Section: Ch-starch [131]mentioning

confidence: 99%

“…Aloe vera [147,183,186,198,224,230] Astaxanthin [161] Berberine [162] Bixin [233] Calendula officinalis [190] Curcumin [134,147,164,186,230,233] Dopamine [125,142] EGCG [145] Moringa oleifera (extract) [109] Ostholamide [158] Quercetin [125] Sesamol [232] Soybean (extract) [167] Thymol [234] Tyramine [145] Vitamin E [142] β-Carotene [234] ALG derivatives [109] Amnion (decellularized hydrogel) [198] Bone matrix (decellularized) [224] .Cellulose acetate-gelatin [162] Cellulose acetate derivatives [232] CH derivatives [116] CH-ALG [234] Collagen [161] Gelatin derivative [186] Gelatin derivatives-collagen [158] HA [145] HA-β-cyclodextrin [142] HPG [190] PA-6 [167] PCL [148,236] PDMS [125] PEG-PCL [134] PLA-HPG [164]…”

Section: Wound Healingmentioning

confidence: 99%

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Repositioning Natural Antioxidants for Therapeutic Applications in Tissue Engineering

Marrazzo

O’Leary

2020

Bioengineering

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Although a large panel of natural antioxidants demonstrate a protective effect in preventing cellular oxidative stress, their low bioavailability limits therapeutic activity at the targeted injury site. The importance to deliver drug or cells into oxidative microenvironments can be realized with the development of biocompatible redox-modulating materials. The incorporation of antioxidant compounds within implanted biomaterials should be able to retain the antioxidant activity, while also allowing graft survival and tissue recovery. This review summarizes the recent literature reporting the combined role of natural antioxidants with biomaterials. Our review highlights how such functionalization is a promising strategy in tissue engineering to improve the engraftment and promote tissue healing or regeneration.

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Section: Towards Therapeutic Application: Antioxidant Biomaterialsmentioning

confidence: 99%

Section: Scavenging Activitymentioning

confidence: 99%

Section: Ch-starch [131]mentioning

confidence: 99%

Section: Wound Healingmentioning

confidence: 99%

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Repositioning Natural Antioxidants for Therapeutic Applications in Tissue Engineering

Marrazzo

O’Leary

2020

Bioengineering

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“…It is an essential component required for the highly ordered structural integrity and tensile strength of the skin (Suh et al, 2018;Kang et al, 2019). Collagen-based biomaterials with different structures have been used for tissue repair and regeneration (Kenar et al, 2019;Gil-Cifuentes et al, 2019). However, the use of collagen alone has some disadvantages such as difficulty in molding and it is fragile.…”

Section: Introductionmentioning

confidence: 99%

Curcumin nanoparticles incorporated in PVA/collagen composite films promote wound healing

Leng

Pang

et al. 2020

Drug Delivery

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Skin repair remains a common problem in plastic surgery. Wound dressing plays an important role in promoting local skin healing and has been widely studied. This study aimed to manufacture a composite film (CPCF) containing curcumin nanoparticles, collagen, and polyvinyl alcohol (PVA) to effectively promote the healing of skin wounds. Sustained drug release from the composite film provides long-term protection and treatment for skin wounds. Both antibacterial property and good histocompatibility of the CPCF were examined by analyzing antibacterial activity and cytotoxicity to validate its applicability for wound management. Moreover, in vivo studies proved that the CPCF had a rapid healing rate of 98.03%±0.79% and mature epithelialization on day 15 after surgery. Obvious hair follicles and earlier re-epithelialization was also noticed in the CPCF group using H&E staining. The result of Masson's trichrome staining confirmed that CPCF could promote the formation of collagen fibers. In summary, CPCF may be promising as a wound dressing agent in wound management owing to its rapid wound-healing effects.

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Herbal bioactive-incorporated scaffolds for wound healing applications

Sharma

Puri

Bakshi

et al. 2022

Herbal Bioactive-Based Drug Delivery Systems

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Evaluation of collagen type I scaffolds including gelatin-collagen microparticles and Aloe vera in a model of full-thickness skin wound

Cited by 17 publications

References 48 publications

Repositioning Natural Antioxidants for Therapeutic Applications in Tissue Engineering

Repositioning Natural Antioxidants for Therapeutic Applications in Tissue Engineering

Curcumin nanoparticles incorporated in PVA/collagen composite films promote wound healing

Herbal bioactive-incorporated scaffolds for wound healing applications

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