Evaluation of Cognitive Functions in Gestational Diabetes Mellitus

Abstract

Our findings may be a clue for early onset of impairment in cognitive functions in cases with new onset diabetes during pregnancy.

Relationship between depression and diabetes in pregnancy: A systematic review

“…Overall, 48 publications were included in this review (Figure 1, Table 1, Table 2, Table 3, Supplementary Table 1). Of these, 30 described prospective observational studies[20,21,23,24,26,27,29-31,34,35,37,38,41,43-45,47-49,51,54,57,58,60-62,65-67], 15 described retrospective observational studies[22,25,28,32,39,40,42,46,50,53,55,56,59,63,64], and three described randomized controlled trials (RCTs)[33,36,52], two of which reported only baseline data[36,52]. Two publications described the same study, but reported different subgroup analyses[23,29].…”

“…A total of 28 studies included only women with GDM[20,23,26-29,31,33,35-38,40,43-45,47-49,51-53,57,58,60,61,63,64], 14 included women with either GDM or pre-existing diabetes (although the type was not always reported)[22,25,39,41,42,46,50,54-56,59,62,65,66], one included women with either GDM or type 1 diabetes[34], one included only women with type 1 diabetes[67], one included only women with pre-existing diabetes (type not reported)[30] and three did not report the type of diabetes[21,24,32] (Tables 1-3, Supplementary Table 1). Sample sizes ranged from 36[65] to more than 32 million in a retrospective analysis of a nationwide hospital database[22] (Tables 1-3, Supplementary Table 1).…”

“…There were 22 studies that measured depression only during pregnancy[22,24,26,30,31,36,37,40,41,43,45,51,53-55,57-59,61,64,66,67]. Conversely, 11 studies focussed on postpartum depression, most commonly measured within the first 3 mo[20,21,23,25,27,29,33,47,52,62,63].…”

“…Among women with GDM (Table 1, Figure 3), the reported prevalence of depression during or after pregnancy ranged widely, from 4.1% to 80% (16 studies[26,31,33,35,39-41,43,44,46,51,52,54,57,58,61], median 14.7%). Heterogeneity in sample size, the definition of depression, and the timing of its assessment is likely to have contributed to this wide range of prevalence rates.…”

Gestational diabetes: An overview with attention for developing countries

“…On the other side, mothers may face complications in shortor long-term. Short-term, they may show high stress level, low sleep quality, and impaired cognitive functions (Hayase et al 2014;Keskin et al 2015). Moreover, they can develop thyroiditis, renal diseases, and type 2 DM (Beharier et al 2015;Hopmans et al 2015;Maleki and Tavosi 2015).…”