2013
DOI: 10.1001/2013.jamadermatol.668
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Evaluation of Clinical Results, Histological Architecture, and Collagen Expression Following Treatment of Mature Burn Scars With a Fractional Carbon Dioxide Laser

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Cited by 168 publications
(155 citation statements)
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References 18 publications
(22 reference statements)
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“…Long-term, persistent gains in function and improvements in scar characteristics probably result from gradual diffuse dermal remodeling and a relative normalization of dysfunctional scar tissue. 5 Despite the promising findings, there are limitations to our results, including the small sample size, the heterogeneity of the patients and treated scars, and the lack of a treatment control. The varied nature of trauma itself confounds the attempt to generate a coherent series at a single center in a reasonable length of time.…”
Section: Discussionmentioning
confidence: 81%
See 1 more Smart Citation
“…Long-term, persistent gains in function and improvements in scar characteristics probably result from gradual diffuse dermal remodeling and a relative normalization of dysfunctional scar tissue. 5 Despite the promising findings, there are limitations to our results, including the small sample size, the heterogeneity of the patients and treated scars, and the lack of a treatment control. The varied nature of trauma itself confounds the attempt to generate a coherent series at a single center in a reasonable length of time.…”
Section: Discussionmentioning
confidence: 81%
“…Recent reports suggest that AFR can result in consistent enhancements in appearance, function, and symptoms, such as pain and itch, in severe traumatic scars. [5][6][7][8][9] Herein we demonstrate objective functional improvements in 2 pediatric patients with debilitating scar contractures treated with AFR. Their ROM gains occurred after both had plateaued with traditional interventions (ie, therapy and surgery) and coincided temporally with laser surgery (Figs 1 and 2).…”
mentioning
confidence: 71%
“…The pursuit of good results in treating photo aging and other disorders with fractional CO 2 laser has been studied widely in recent years [14][15][16] , demonstrated in ten patients that lesion depth was proportional to increases in pulse duration.…”
Section: Discussionmentioning
confidence: 99%
“…Histologically, scars treated with fractional laser have significantly decreased type I collagen and increased type III collagen which is more similar to normal skin than untreated lesions. 14,15 And what's more, vascular density in the superficial dermis is also improved. 16 There are several reports about using ablative fractional laser in treatment of postsurgical and burns scars.…”
Section: Case Reportmentioning
confidence: 99%