Evaluation of Cicatricial Alopecia in Iran

Abstract

Cicatricle alopecia represents a diverse group of diseases characterized by a lack of follicular ostia and irreversible alopecia. This study aimed at evaluating cicatricial alopecia in Iranian patients. One hundred patients with cicatricial alopecia were studied. Patients disease was pathologically proven. All epidemiologic and clinicopathologic data were obtained through questionnaires. The results were analyzed by means of descriptive statistical methods. One hundred patients were consisted of 52 (52%) males and 48 (48%) females. 30 patients (24 males and 6 females) suffered from folliculate decalvans, 25 cases (10 males and 15 females) from DLE, 18 patients (6 males and 11 females) from brocq pseudopelade, 14 patients (4 males and 10 females) from lichen planopilaris, 8 patients (4 males and 4 females) from morphea and 5 cases (4 males and 1 female) from folliculate colloidalis. Early stage diagnosis by biopsy and proper treatment will reduce further progression and especially alleviate psychosocial disturbances.

An epidemiological study of 97 cases of primary cicatricial alopecia in Iran

“…5 , 6 , 10 , 11 However, there are studies which reported FD and PPB as the most common type. 3 , 7 , 8 Another observation in the present study was that the ratio of lymphocytic PCA to neutrophilic/other types of PCA was 5.5:1. This ratio was 7.4:1, 8.5: 1, 0.78:1, and 1.86:1 in other studies.…”

“… 3 , 5 , 6 , 9 In contrast, a study in Iran showed that PCA affected male patients more commonly. 8 This inconsistency can be attributed to the fact that a high percentage of PCA cases in this reference were of the neutrophilic type. Indeed, past research has shown that neutrophilic PCA is more common in middle-aged men, but lymphocytic PCA is more frequently seen among middle-aged women.…”

Clinico-epidemiology and histopathologic spectrum of primary scarring alopecia: A cross-sectional study

“…In the present study, the majority of patients were middle-aged belonging to 30–39 years age group, showing a female predilection (M: F 1:1.2) consistent with most previous studies[ 1 8 10 11 14 ], while some authors reported male preponderance. [ 5 15 16 ] Two Iranians reported a higher mean age of patients—39.1[ 10 ] and 37 years,[ 14 ] along with a Spanish study (53.5 years)[ 17 ]; in contrast, mean age of our patients was much lower—30.9 years (SD 8.1). Females are more likely to consult dermatologists for hair loss, due to their aesthetic concerns; thus explaining the female predominance in most studies.…”

Primary Cicatricial Alopecia among Lybian patients: A Clinicopathological and Epidemiological study

“…This might clarify by the fact that females are more probable to ask for medical consultation for skin disorders. On the other hand, a study conducted in Iran reported that 52% patients were males; this may due to the higher amount of neutrophilic cicatricial alopecia that frequently affects male [3]. Certainly, earlier study has revealed that neutrophilic cicatricial alopecia is more frequently seen in middle-aged males, and that lymphocytic cicatricial alopecia is more common among middle-aged females [8].…”

“…It presents as a loss of follicular ostia in clinical manifestation and destruction of hair follicle in histological investigation [2]. Patients affected by scarring alopecia present with symptoms including; pain, burning, severe itching, quick disease progression, and gradual hair loss [3].…”