An epidemiological study of 97 cases of primary cicatricial alopecia in Iran

Beheshtiroy, Akram; Hajmanoochehri, Fatemeh; Hossienghamar, Fahim

doi:10.4081/dr.2015.5960

Cited by 12 publications

(31 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These results suggest that the female preponderance among Caucasian patients may be attributed to lymphocytic concentrations, which were fourfold higher than neutrophils in previous reports . In contrast, a different study showed male predominance among PCA patients . The female : male ratio in the study was 1.7:1, and the ratio was 1.9:1 for the lymphocytic subtype and 1:1.5 for the neutrophilic group.…”

Section: Discussioncontrasting

confidence: 63%

“…3 In contrast, a different study showed male predominance among PCA patients. 6 The female : male ratio in the study was 1.7:1, and the ratio was 1.9:1 for the lymphocytic subtype and 1:1.5 for the neutrophilic group. In addition, we observed a high prevalence of neutrophilic PCA.…”

Section: Discussionmentioning

confidence: 68%

“…The UK incidence of PCA cases was 6.96 per 1000 new general dermatology referrals per year, equating to approximately 9.6 new cases per clinician per year. The male : female ratios were different depending on the subtypes of PCA, and PCA was most common in middle‐aged patients in a retrospective study in Asia . However, these studies were clinic‐based and limited by small sample size.…”

Section: Introductionmentioning

confidence: 99%

“…The male : female ratios were different depending on the subtypes of PCA, and PCA was most common in middle-aged patients in a retrospective study in Asia. 6 However, these studies were clinic-based and limited by small sample size. No study has investigated the epidemiology using a large population-based sample yet.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Primary cicatricial alopecia in a single‐race Asian population: A 10‐year nationwide population‐based study in South Korea

Yoon

Choi

2018

The Journal of Dermatology

View full text Add to dashboard Cite

Primary cicatricial alopecia (PCA) is a dermatological challenge. Because no large-scale epidemiological study regarding PCA is available yet, we investigated the National Health Insurance Service-National Sample Cohort for patients diagnosed with PCA. The annual and overall rates of incidence and prevalence of PCA during the study period (2004-2013) were estimated. Distribution of PCA subtypes, disease co-occurrence rates and frequently prescribed medications were also evaluated. The overall incidence was 6.10 (95% confidence interval [CI], 5.62-6.60) per 100 000 person-years. The incidence rate was stable over time (risk ratio [RR] = 1.012, P = 0.201) and lower in female patients (RR = 0.718, P < 0.001). The overall prevalence was 20.93 (95% CI, 17.97-23.86) per 100 000 persons. The average duration of PCA was calculated as 3.23 years. Approximately 70% of the patients were below the age of 45 years. Folliculitis decalvans and dissecting cellulitis were the most common subtypes of PCA. Logistic regression analysis showed that PCA was significantly associated with thyroid disorders (adjusted odds ratio = 1.64, P < 0.001). Clobetasol was the most frequently prescribed topical agent. Corticosteroids were the most common oral agents used, followed by tetracycline antibiotics. Our study is the first large-scale study reporting the epidemiology of PCA. We found a preponderance of males and neutrophil-associated subtypes of PCA, and PCA was related to thyroid disorders.

show abstract

Section: Discussioncontrasting

confidence: 63%

Section: Discussionmentioning

confidence: 68%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Primary cicatricial alopecia in a single‐race Asian population: A 10‐year nationwide population‐based study in South Korea

Yoon

Choi

2018

The Journal of Dermatology

View full text Add to dashboard Cite

show abstract

“…Mean age at the time of presentation in our patients was almost similar to other studies in our region; however, f/m ratio is higher than Abedini et al . but similar to Beheshtiroy . In most surveys, LPP was more common in females .…”

Section: Discussionsupporting

confidence: 88%

Dermoscopic features of lichen planopilaris in Northern Iran: a prospective observational study

et al. 2019

View full text Add to dashboard Cite

Background Dermoscopy can be helpful in assessing nonpigmented lesions and inflammatory processes like lichen planopilaris (LPP). Material & Methods In this observational prospective study, 81 patients with a cicatricial alopecic patch on their scalp were included and underwent dermatologic examination. A biopsy was taken from the active part of the lesion based on dermoscopy evaluation. Results Analysis of 44 patients with definite diagnosis of LPP revealed that the mean age at the time of presentation was 44.05 ± 12.62 years. More than 77% of patients had at least one form of the follicular opening disorder. About 75% of patients had shaft disorders. The most common pattern of pigmentation was milky‐red (97.73%). The irregular and ectatic vascular network were seen in 59.09% of patients. Patients with coiled and twisted hairs, small yellow dots, large yellow dots, and peripilar sign were more likely to have shorter disease duration (P < 0.05). Those with overall shaft disorders were younger (P = 0.02). Small yellow dots (P = 0.025) and peripilar sign (P = 0.039) were more common in female patients. Conclusion Dermoscopy can be a helpful diagnostic tool in differentiating LPP among patients with primary cicatricial alopecia (PCA). Larger cohort studies are recommended to find the role of demographic factors in predicting the dermoscopic patterns among LPP patients.

show abstract

Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women

Saqib

Bhat

Shah

et al. 2021

International Journal of Women's Dermatology

View full text Add to dashboard Cite

Background Alopecia in women is generally difficult to diagnose clinically. Trichoscopy may help make the correct diagnosis in doubtful cases. Objective The aims of the study were to assess the trichoscopic features of different types of alopecia in women, the reliability of trichoscopy vis-à-vis clinical findings, and the validity of trichoscopy in cases with a doubtful clinical diagnosis. Methods A hospital-based observational, cross-sectional study was carried out on female patients with alopecia. A trichoscopic diagnosis was made and correlated with a clinical diagnosis. The validity of trichoscopy in doubtful cases was evaluated by reporting the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic value. Results On trichoscopy, increased hair diameter diversity > 20%, single-hair follicular unit, vellus hair, peripilar sign, and focal atrichia were commonly seen in female pattern hair loss. In telogen effluvium, there was a scarceness of specific findings. In cicatricial alopecias, loss of follicular ostia, erythema, white macules, blue-gray dots, white dots, tufted hair, and keratotic follicular plugging were observed. A good agreement between trichoscopy and clinical diagnosis was found (Cohen’s Kappa = 0.824; 95% confidence interval, 0.756–0.892). The validity of trichoscopy in doubtful cases was evaluated using the validity parameters, which were high in all alopecias. Limitations Histopathology testing was not done in all patients. Conclusion Trichoscopy helped reach a definitive diagnosis in patients in whom the clinical diagnosis was doubtful. Thus, trichoscopy is a sensitive and specific investigation that can be valuable in women with alopecia.

show abstract

An epidemiological study of 97 cases of primary cicatricial alopecia in Iran

Cited by 12 publications

References 12 publications

Primary cicatricial alopecia in a single‐race Asian population: A 10‐year nationwide population‐based study in South Korea

Primary cicatricial alopecia in a single‐race Asian population: A 10‐year nationwide population‐based study in South Korea

Dermoscopic features of lichen planopilaris in Northern Iran: a prospective observational study

Assessment, reliability, and validity of trichoscopy in the evaluation of alopecia in women

Contact Info

Product

Resources

About