Evaluation of characteristics of high-energy electron beams using N-isopropyl-acrylamide gel dosimeter

Shih, Tian Yu; Yen, Tsung Hsien; Liu, Yan Lin; Luzhbin, Dmytro; Wu, Jen-Ming

doi:10.1016/j.radphyschem.2017.02.022

Cited by 9 publications

(2 citation statements)

References 13 publications

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“…This feature also depends on the type of gel and on the experimental technique used to measure the dose. In the case of MRI acquisitions, the sensitivity is the slope of the R

dose response curve and is reported as Gy

and was found to be in a range between 0.03 and 8.93 Gy

[ 55 , 62 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 ]. Recently, addition of high atomic elements (such as bismuth, gadolinium, silver or gold nanoparticles, etc.)…”

Section: Polyacrylamide Gelsmentioning

confidence: 99%

Hydrogels for Three-Dimensional Ionizing-Radiation Dosimetry

Marrale

D’Errico

2021

Gels

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Radiation-sensitive gels are among the most recent and promising developments for radiation therapy (RT) dosimetry. RT dosimetry has the twofold goal of ensuring the quality of the treatment and the radiation protection of the patient. Benchmark dosimetry for acceptance testing and commissioning of RT systems is still based on ionization chambers. However, even the smallest chambers cannot resolve the steep dose gradients of up to 30–50% per mm generated with the most advanced techniques. While a multitude of systems based, e.g., on luminescence, silicon diodes and radiochromic materials have been developed, they do not allow the truly continuous 3D dose measurements offered by radiation-sensitive gels. The gels are tissue equivalent, so they also serve as phantoms, and their response is largely independent of radiation quality and dose rate. Some of them are infused with ferrous sulfate and rely on the radiation-induced oxidation of ferrous ions to ferric ions (Fricke-gels). Other formulations consist of monomers dispersed in a gelatinous medium (Polyacrylamide gels) and rely on radiation-induced polymerization, which creates a stable polymer structure. In both gel types, irradiation causes changes in proton relaxation rates that are proportional to locally absorbed dose and can be imaged using magnetic resonance imaging (MRI). Changes in color and/or opacification of the gels also occur upon irradiation, allowing the use of optical tomography techniques. In this work, we review both Fricke and polyacrylamide gels with emphasis on their chemical and physical properties and on their applications for radiation dosimetry.

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“…This feature also depends on the type of gel and on the experimental technique used to measure the dose. In the case of MRI acquisitions, the sensitivity is the slope of the R

dose response curve and is reported as Gy

and was found to be in a range between 0.03 and 8.93 Gy

[ 55 , 62 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 ]. Recently, addition of high atomic elements (such as bismuth, gadolinium, silver or gold nanoparticles, etc.)…”

Section: Polyacrylamide Gelsmentioning

confidence: 99%

Hydrogels for Three-Dimensional Ionizing-Radiation Dosimetry

Marrale

D’Errico

2021

Gels

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“…In recent years, gel dosimeters are gradually being employed for dose assessment 16 – 18 in medical applications. Gel dosimeters provide three-dimensional (3D) dose measurements and have a number of exceptional characteristics such as tissue equivalence, high spatial resolution, low energy dependence, and low dose rate dependence.…”

Section: Introductionmentioning

confidence: 99%

Dose and slice thickness evaluation with nMAG gel dosimeters in computed tomography

Chuang

2018

Sci Rep

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Computed tomography (CT) has been widely used in clinical diagnosis. It is important to estimate radiation dose and perform image quality assurance procedures for CT scans. In this study, nMAG gel dosimeters were used to simultaneously measure the 300-mm weighted CT dose index (CTDI) and slice sensitivity profile (SSP) for multiple detector CT (MDCT). Magnetic resonance imaging (MRI) was performed on the irradiated gel to create R2‒dose response curves for the tube voltages of 120 and 140 kVp. The gel dosimeters were loaded in three home-made cylindrical phantoms to obtain CTDI100 and CTDI300. The full width at half maximum (FWHM) for 2, 5, 10, 14.4, and 38.4-mm slice thicknesses was measured and compared with the result obtained by radiochromic films. The difference in weighted CTDI100 obtained by the gel dosimeter and ionization chamber was less than 1%. The CTDI efficiency at 120 and 140 kVp was in the range of 80.1%–82.5%. The FWHM of SSP measured by the gel dosimeter matched very well with the nominal slice thickness. The use of nMAG gel dosimeters combined with the home-made cylindrical phantoms can provide 300-mm weighted CTDI and slice thickness information, showing potential for quality assurance and clinical applications in MDCT.

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