Evaluation of Brain Tumours by Mri Techniques and Their Histopathological Correlation

Abstract

This study was conducted on thirty patients of brain tumors diagnosed on CT scan/ Conventional MRI. It was performed in the Department of Radiological and PET Imaging, Institute of Nuclear Medicine and Allied Sciences (INMAS), Brig S. K. Mazumdar Marg , Lucknow road, Delhi. Out of thirty patients, 19 patients (63.33%) were male and 11 patients (36.66%) were female. Their ages ranged from 22 to 63 years. The most common presenting symptom was headache followed by seizures. MRI is a powerful tool for evaluation and characterization of brain tumors because of its superior soft tissue contrast and multiplanar capabilities. All these patients underwent routine MRI sequences, including T1W, T2WI and FLAIR sequences. Histopathological correlation was obtained in all the patients to serve as the gold standard. Out of thirty patients selected for this study, twenty cases were found to be malignant and ten cases were benign on histopathological evaluation. Majority of malignant lesions were glioblastomamultiforme. Amongst benign cases, majorities were meningioma, one was a granulomatous lesion and one was a benign cystic lesion. On conventional MRI sequences, including T1, T2 and FLAIR, there was significant overlap between appearances of benign and malignant lesions in their intensity on various sequences. Moreover, it has got no prognostic value in follow up of patients after therapy.

Difusión y relaxometría por resonancia magnética nuclear en tumores cerebrales

“…Se acepta que la resonancia magnética (RM) convencional no es suficiente para discriminar la extensión de la parte invasiva del tumor. La RM funcional está aportando información complementaria de gran importancia en la caracterización, planificación terapéutica, y diagnóstico de los tumores cerebrales, también es una herramienta poderosa para la evaluación y caracterización de tumores cerebrales debido a su contraste superior a los tejidos blandos y su capacidad multiplanar [15], [16]. Los avances de las técnicas de resonancia magnética están proporcionando una mejor información en el diagnóstico y en lo terapéutico, solo se puede hacer un marcador sustituto de procesos fisiológicos y patológicos; hasta que se pueda usar rutinariamente para obtener imágenes del cerebro a nivel celular, la resonancia magnética siempre será un estudio secundario para la patología en la evolución del diagnóstico final [17].…”