Evaluation of Bond Strength and Microleakage of a Novel Metal-titanate Antibacterial Agent

Abstract

Incorporating nMT into a dental adhesive system will not compromise the resin composite's tooth bonding and sealing ability.

Adhesive systems modified with antimicrobial agents: a literature review

“…37,38 The basic components of the adhesive system are: conditioning agent, primer and adhesive, in addition to photo initiators, polymerization inhibitors, and inorganic fillers. 33 They can also be modified with antimicrobial agents, [1][2][3][4][5][6][7][8][9][10][11][12][15][16][17][18][19][20]22,24,26,[28][29][30][31][39][40][41][42][43][44] mineralizing agents, 2,3,16,22,26,30,45 protein repellent, 2 inhibitors of metalloproteinases, 6,46,47 and even inti-inflammatory agents. 5 The understanding of the function of each system component and their careful use, respecting their indications, will be essential for adhesion success.…”

“…9,52 Many researchers develop new antimicrobial adhesives, or modify the materials available in the market with the addition of antimicrobial agents as a resort to secondary caries inhibiting mechanisms. [1][2][3][4][5][6][7][8][9][10][11][12][15][16][17][18][19][20]22,24,26,[28][29][30][31][39][40][41][42][43][44] Thus, the addition of benefit with potential to increase restoration longevity is desired. 16,52 In this context, nanotechnology has been used in caries prevention.…”

“…52,55 thus, they have a mechanism of action by contact and do not lose their effectiveness, since they are incorporated in the polymeric matrix. 15 Other antibacterial strategies incorporated into dental biomaterials include titanium dioxide (TiO 2 ), 24 zinc oxide (ZnO), 24 bio-active glass (BAG) doped with Ag 2 O or ZNO, 26 silver methacrylate (Ag), 40 di-n-butildimetacrilatetin (Sn), 40 nanoparticulate with titanate metal complex (nMT), 43 polyacrylic acid copper iodine (PAA-CuI), 17 arginine, 9 nisin peptides, 18 [ 30,31 , glutaraldehyde, 12,44 ch lorhex id i ne (CH X), 12, 4 4 na noc apsu le s of triclosan, 5 quercetin, 6 natural essential oils. 59 The use of antimicrobial agents pre-treating the dentin before adhesive procedures are poly (ɛ-prolactone) nanocapsules loaded with chlorhexidine (nano PCL/ CHX), 47 nanoparticles of poly (lactic-co-glycolic acid) loaded with chlorhexidine (nano PLGA-CHX), 46 and grape seed extract (e-GSE).…”

“…27 Moreover, some of these studies used experimental adhesives; 9,11,22,28,30,31,40,41 others used commercially available antimicrobial adhesives, such as Clearfil Protect Bond (MDPB), 12,17,20,27,42,44 Gluma 2 Bond (glutaraldehyde), 12,44 and Peak universal bond (chlorhexidine); 12,44 or conventional commercial adhesives combined with antimicrobial agents. [1][2][3][4][5][6][7][8]10,[15][16][17][18][19][20]24,26,29,39,42,43 Therefore, given the diversity of new agents of union with antimicrobial activity, the analysis of the results of these studies requires caution.…”

Propiedades antimicrobianas y citotóxicas de un adhesivo de uso ortodóncico adicionado con nanopartículas de plata

“…El mip más comúnmente utilizado es Transbond mip (3M Unitek, Monorovia, California, EUA) Transbond mip permite la adhesión en un entorno húmedo sin comprometer su fuerza de adhesión. Se han publicado numerosos estudios in vitro sobre la efectividad de este adhesivo (Littlewood et al, 2000;Webster et al, 2001;Anand et al, 2014;Deng et al, 2016;Grandhi y Combe, 2001).…”