Evaluation of biochemical parameters and some antioxidants indicators in lactating Nubian and Karachai goats under Russian conditions

Abstract

The study’s aim was to assess determine the physiological and biochemical status of lactating Nubian and Karachai goats depending on breed and lactation number, as well as to identify correlations between blood biochemical parameters and some antioxidant indicators. Our experiment was divided into two groups for this purpose: the first (comparative group) included Nubian goats (n= 22) and Karachai goats (n= 67), while the second (general group) included Nubian goats (n= 43) and Karachai goats (n= 93). In the comparative group, the levels of total protein, urea, alanine amino transferase (ALT), glucose, total bilirubin, alkaline phosphatase and thiobarbituric acid reactive substances (TBARS), calcium, phosphorus and magnesium were significantly higher in Karachai goats compared to Nubian goats. In the comparable group, lactation number had a significant effect on calcium and alkaline phosphatase but had no effect on other parameters. Correlations were moderately positive between TBARS level and albumin (0.34), cholesterol (0.34), alkaline phosphatase (0.39), phospholipids (0.43), and calcium (0.35) in Nubian goats. On the other hand, were found moderate negative correlations between ceruloplasmin level and albumin (-0.30), A/G (-0.37), magnesium (-0.35), and the total content of water-soluble antioxidants (TAWSA) (-0.40) in Nubian goats. In Karachai goats, there were moderate positive correlations between TBARS level and albumin (0.41), phospholipids (0.41). However, there was found a very strong negative correlation between ceruloplasmin level and TBARS/CP ratio (-0.67). Total protein, albumin, and ceruloplasmin levels in the general group increased as lactation number increased. Aspartate amino transferase (AST), TBRAS, and TBRAS/CP levels were decreased after the second lactation, and TAWSA decreased from I to IV lactation. Moderate positive correlations between TBARS and albumin (0.44), total protein (0.32), and magnesium (0.33). On the other hand, moderate negative correlations were established between ceruloplasmin level and total protein (-0.30), bilirubin (-0.43), triglycerides (-0.32), ALT (-0.30), TAWSA (-0.31).