Evaluation of bioactive compounds and antioxidant potential of hydroethanolic extract of Moringa oleifera Lam. from Rajasthan, India

Vats, Sharad; Gupta, Tanya

doi:10.1007/s12298-016-0407-6

Cited by 69 publications

(26 citation statements)

References 41 publications

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“…However, it was slightly lower than that reported by Sreelatha and Padma [27] in mature leaves of M. oleifera (45.81 mg GAE g DW and 27 mg QE g DW, respectively). The highest content of vitamin C (5.84 mg AA g DW) observed in this study was higher than that reported by Vats and Gupta [26] (2.80 mg AA g DW); however, it was lower than that reported by Sreelatha and Padma [27] in mature leaves of M. oleifera (6.60 mg AA g DW).…”

Section: Resultscontrasting

confidence: 81%

“…The same dose also increased the antioxidant capacity of ABTS, DPPH, and FRAP by 21%, 2.7% and 6.3%, respectively. The highest content of phenols (20.80 mg GAE g DW) and flavonoids (42.20 mg QE g DW) observed in leaves of M. oleifera (Table 1) was higher than reported by Vats and Gupta [26] (9.58 mg GAE g DW and 2.3 mg QE g DW, respectively). However, it was slightly lower than that reported by Sreelatha and Padma [27] in mature leaves of M. oleifera (45.81 mg GAE g DW and 27 mg QE g DW, respectively).…”

Section: Resultscontrasting

confidence: 51%

“…In general, there is a clear trend that the foliar application of Cu NPs to M. oleifera plants induces a decrease in the biocompounds in the fruits of this plant. However, the concentrations of biocompounds, such as total phenols, β-carotene, and lycopene, were higher in the leaves of M. oleifera than in the rest of the organs [26]. In addition, the leaf of M. oleifera represents the largest proportion of biomass in the plant; therefore, the increase in biocompounds observed in this organ is more important than a decrease in the fruits.…”

Section: Resultsmentioning

confidence: 88%

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Foliar Application of Cu Nanoparticles Modified the Content of Bioactive Compounds in Moringa oleifera Lam

Juárez-Maldonado

Ortega-Ortíz²,

Cadenas‐Pliego³

et al. 2018

Agronomy

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Moringa oleifera Lam is a plant that has recently gained importance as a food because of its nutritional value and bioactive compound content and because practically all the organs are usable. The use of nanoparticles has appeared as an alternative to increase bioactive compounds in plants. The goal of this work was to determine if the application of copper nanoparticles would increase the content of bioactive compounds and antioxidant capacity in M. oleifera. Copper (Cu) nanoparticles were applied to the leaves at four different times throughout crop growth. The biocompounds were analyzed after the second, third, and fourth applications. The results show that application of Cu nanoparticles has a beneficial effect on the accumulation of bioactive compounds in M. oleifera leaves. In addition, the antioxidant capacity and carotenoid and chlorophyll contents in the leaves of M. oleifera increased after Cu nanoparticles application. The same effect was not observed in the fruit of M. oleifera. Here, the bioactive compound contents diminished. Therefore, the use of Cu nanoparticles can be an important alternative to improve the quality of this plant, particularly that of the leaves.

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Section: Resultscontrasting

confidence: 81%

Section: Resultscontrasting

confidence: 51%

Section: Resultsmentioning

confidence: 88%

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Foliar Application of Cu Nanoparticles Modified the Content of Bioactive Compounds in Moringa oleifera Lam

Juárez-Maldonado

Ortega-Ortíz²,

Cadenas‐Pliego³

et al. 2018

Agronomy

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“…The aqueous extract of the leaf, with phytochemical compounds, was an important target in neural studies, with action of nicotine, the authors revealed that the aqueous extract was able to prevent chromatolysis, distortion of cerebellar cortical cells and neurobehavioral deficit, in mice treated with nicotine [16]. The hydroethanolic extract of the leaves showed antioxidant activity [17]. Hani, et al [18] found that the leaf extract of MO, with secondary metabolites, maintained its antioxidant activity after encapsulation and that it is safe for oral consumption.…”

Section: Resultsmentioning

confidence: 99%

<em>MORINGA OLEIFERA</em>: A NEW PERSPECTIVE FOR THE SYNTHESIS OF NATURAL PRODUCTS

Silva

Bezerra

Sousa

et al. 2018

Proceedings of MOL2NET 2018, International Conference on Multidisciplinary Sciences, 4th Edition

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Moringa oleifera Lam. is a plant native from India, but its distribution extends to all continents. Its leaves, flowers, pods and seeds are commonly used for food, mainly in Africa, due to its high nutritional value. With regard to medicine, M. oleifera demonstrates immeasurable potential in view of the various biological activities which are reported from its secondary compounds, such as alkaloids, tannins, flavonols, steroids, saponins, coumarins, quinones, resins, lectins among others. Based on this assumption, this review aims to expose the potential of Moringa oleifera in the period 2016-2018, in the use of its compounds for the synthesis of natural products due to its diverse biological activities. The results showed that the several parts of the plant may have different biological activities. The seeds have antibacterial activity with dental importance; activity in the prevention and deceleration of the amyotrophic lateral sclerosis disease (ALS); anti-hypertrophic and anti-fibrotic effect, being beneficial for cardiac structure and function in hypertensive mice; anticancer activity; anti-inflammatory; and protection of neural cells. For the leaves were reported Antitumor activities; therapeutic efficacy against neurotoxicity; for insulin expression and decrease in the degree of insulitis; antimicrobial activity; reduction of myocardial damage and oxidative stress; treatment in atopic dermatitis; gastroprotective activity and improvement of mucus; hypocholesterolemic effect; and ability to prevent chromatolysis, distortion of cerebellar cortical cells and neurobehavioral deficit. For the other parts of the plant similar activities are described, however in less quantity. Thus, Moringa oleifera presents a new perspective on the synthesis of natural products, considering the range of biological activities described for a species, as well as the ease of obtaining and using its compounds.

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“…Similar results were reported by Sharad and Gupta, while studying the bioactive compounds and antioxidant activity of Moringo olefera hydroethanolic extract. 33 Further it was concluded that J. squamata possesses a good reducing power ability. The ferric reducing power activity of different extracts of J. squamata seems to be due to the presence of polyphenols which is correlated to its total phenolic content.…”

Section: Hydroxyl Radical Scavenging Activity Radicalmentioning

confidence: 99%

Evaluation of Antioxidant and Immunomodulatory Potential of Methanolic Extract of Juniperus squamata Buch.-Ham. ex D.Don

Ali

Sajjad

Qureshi

et al. 2018

FRA

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Background: Antioxidant plays a vital role in scavenging of free radicals, thus, providing protection against oxidative stress. Now the modern research is directed towards the discovery of herbal antioxidants and immnomodulators due to their lesser side effects. Objective: The aim of the present study is to evaluate the antioxidant and immunomodulatory potential of methanolic extract of Juniperus squamata from the Apharwat region of Gulmarg. Materials and method: The antioxidant activity of methanol extract of Juniperus squamata was evaluated by using 1, 1-diphenyl, 2-picrylhydrazyl (DPPH) scavenging, reducing power, hydroxyl radical scavenging, hydrogen peroxide scavenging activity and lipid peroxidation. Furthermore, the immunomodulatory potential of the extracts was investigated through the Delayed type hypersensitivity and phagocytic carbon clearance assay. Results: The highest phenolic content of 780 GAE/g (Total phenolic content) was observed in the methanolic extract, while the lowest Total phenolic content of 459 mg GAE/g was achieved in the petroleum ether extract. At a concentration of 700 g/mL, DPPH radical scavenging activity was found to be highest in methanolic extract (82.12%). Methanol extract was found to be an efficient scavenger of hydrogen peroxide radical and lipid peroxidation with IC 50 values of 161.44 ± 0.08 μg/mL and 78.65 μg/mL respectively. Administration of plant extract (100 and 200 mg/kg body weight) increased the DTH response and phagocytic carbon clearance significantly. Conclusion: The results indicate that the methanolic leaf extract of Juniperus squamata has good antioxidant and immunomodulatory potential.

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Evaluation of bioactive compounds and antioxidant potential of hydroethanolic extract of Moringa oleifera Lam. from Rajasthan, India

Cited by 69 publications

References 41 publications

Foliar Application of Cu Nanoparticles Modified the Content of Bioactive Compounds in Moringa oleifera Lam

Foliar Application of Cu Nanoparticles Modified the Content of Bioactive Compounds in Moringa oleifera Lam

<em>MORINGA OLEIFERA</em>: A NEW PERSPECTIVE FOR THE SYNTHESIS OF NATURAL PRODUCTS

Evaluation of Antioxidant and Immunomodulatory Potential of Methanolic Extract of Juniperus squamata Buch.-Ham. ex D.Don

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